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Our evolving understanding of migraine with aura.
Curr Pain Headache Rep 2014; 18(10):453CP

Abstract

Migraine aura consists of fully reversible focal neurologic symptoms that may precede or coexist with headache in a significant minority of migraine patients. Typical aura symptoms include visual, sensory, and language disturbances. The most recent International Classification of Headache Disorders, 3rd edition (beta version) has added other aura types such as brainstem localizing symptoms, lateralizing weakness, and monocular visual loss. Currently available data from animal models and functional neuroimaging in humans implicate cortical spreading depression (CSD) as the phenomenon underlying migraine aura. Ongoing study suggests that susceptibility to migraine aura and CSD may be genetically mediated. CSD appears to be a potential target for future development of migraine-specific preventive therapies.

Authors+Show Affiliations

Mayo Clinic, 200 W First Street, Rochester, MN, 55905, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

25230799

Citation

DeLange, Justin M., and F Michael Cutrer. "Our Evolving Understanding of Migraine With Aura." Current Pain and Headache Reports, vol. 18, no. 10, 2014, p. 453.
DeLange JM, Cutrer FM. Our evolving understanding of migraine with aura. Curr Pain Headache Rep. 2014;18(10):453.
DeLange, J. M., & Cutrer, F. M. (2014). Our evolving understanding of migraine with aura. Current Pain and Headache Reports, 18(10), p. 453. doi:10.1007/s11916-014-0453-0.
DeLange JM, Cutrer FM. Our Evolving Understanding of Migraine With Aura. Curr Pain Headache Rep. 2014;18(10):453. PubMed PMID: 25230799.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Our evolving understanding of migraine with aura. AU - DeLange,Justin M, AU - Cutrer,F Michael, PY - 2014/9/19/entrez PY - 2014/9/19/pubmed PY - 2015/5/20/medline SP - 453 EP - 453 JF - Current pain and headache reports JO - Curr Pain Headache Rep VL - 18 IS - 10 N2 - Migraine aura consists of fully reversible focal neurologic symptoms that may precede or coexist with headache in a significant minority of migraine patients. Typical aura symptoms include visual, sensory, and language disturbances. The most recent International Classification of Headache Disorders, 3rd edition (beta version) has added other aura types such as brainstem localizing symptoms, lateralizing weakness, and monocular visual loss. Currently available data from animal models and functional neuroimaging in humans implicate cortical spreading depression (CSD) as the phenomenon underlying migraine aura. Ongoing study suggests that susceptibility to migraine aura and CSD may be genetically mediated. CSD appears to be a potential target for future development of migraine-specific preventive therapies. SN - 1534-3081 UR - https://www.unboundmedicine.com/medline/citation/25230799/Our_evolving_understanding_of_migraine_with_aura_ L2 - https://dx.doi.org/10.1007/s11916-014-0453-0 DB - PRIME DP - Unbound Medicine ER -