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[Contribution of omega-3 fatty acids for memory and cognitive function].
Nutr Hosp. 2014 Sep 01; 30(3):467-77.NH

Abstract

INTRODUCTION

A decline in memory and cognitive function is considered to be a normal consequence of aging. Polyunsaturated omega-3 fatty acids are increasingly proposed as dietary supplements with the ability to reduce the risk of cognitive decline, including Alzheimer's disease (AD).

AIM

To study the effect of omega-3 on cognitive decline through the review of recent observational, interventional, and experimental studies.

METHODS

We conducted a Pubmed, Medline, Cochrane and Embase search for epidemiological and clinical studies in the international literature using combinations of the following keywords: "Alzheimer's disease", "mild cognitive impairment", "cognitive function", "dietary factors", "omega-3 fatty acids", "EPA and DHA".

CONCLUSIONS

Studies have shown the protective role of omega-3 fatty acids in mild cognitive impairment, dementia, and the risk and progression of Alzheimer's disease in the elderly. Further studies are needed to understand the mechanism of action of omega-3 fatty acids on cognition. Doses, composition of EPA and DHA capsules and time of supplementation should be explored.

Authors+Show Affiliations

Departamento de Gastroenterología de la Facultad de Medicina de la Universidad de São Paulo.. dan@ganep.com.br.Laboratorio de Investigación Médica LIM 35 - FMUSP. Brasil.. prigarla@gmail.com.

Pub Type(s)

English Abstract
Journal Article
Review

Language

spa

PubMed ID

25238820

Citation

Waitzberg, Dan L., and Priscila Garla. "[Contribution of Omega-3 Fatty Acids for Memory and Cognitive Function]." Nutricion Hospitalaria, vol. 30, no. 3, 2014, pp. 467-77.
Waitzberg DL, Garla P. [Contribution of omega-3 fatty acids for memory and cognitive function]. Nutr Hosp. 2014;30(3):467-77.
Waitzberg, D. L., & Garla, P. (2014). [Contribution of omega-3 fatty acids for memory and cognitive function]. Nutricion Hospitalaria, 30(3), 467-77. https://doi.org/10.3305/nh.2014.30.3.7632
Waitzberg DL, Garla P. [Contribution of Omega-3 Fatty Acids for Memory and Cognitive Function]. Nutr Hosp. 2014 Sep 1;30(3):467-77. PubMed PMID: 25238820.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Contribution of omega-3 fatty acids for memory and cognitive function]. AU - Waitzberg,Dan L, AU - Garla,Priscila, Y1 - 2014/09/01/ PY - 2014/9/21/entrez PY - 2014/9/23/pubmed PY - 2016/7/29/medline SP - 467 EP - 77 JF - Nutricion hospitalaria JO - Nutr Hosp VL - 30 IS - 3 N2 - INTRODUCTION: A decline in memory and cognitive function is considered to be a normal consequence of aging. Polyunsaturated omega-3 fatty acids are increasingly proposed as dietary supplements with the ability to reduce the risk of cognitive decline, including Alzheimer's disease (AD). AIM: To study the effect of omega-3 on cognitive decline through the review of recent observational, interventional, and experimental studies. METHODS: We conducted a Pubmed, Medline, Cochrane and Embase search for epidemiological and clinical studies in the international literature using combinations of the following keywords: "Alzheimer's disease", "mild cognitive impairment", "cognitive function", "dietary factors", "omega-3 fatty acids", "EPA and DHA". CONCLUSIONS: Studies have shown the protective role of omega-3 fatty acids in mild cognitive impairment, dementia, and the risk and progression of Alzheimer's disease in the elderly. Further studies are needed to understand the mechanism of action of omega-3 fatty acids on cognition. Doses, composition of EPA and DHA capsules and time of supplementation should be explored. SN - 1699-5198 UR - https://www.unboundmedicine.com/medline/citation/25238820/[Contribution_of_omega_3_fatty_acids_for_memory_and_cognitive_function]_ DB - PRIME DP - Unbound Medicine ER -