Abstract
INTRODUCTION
A decline in memory and cognitive function is considered to be a normal consequence of aging. Polyunsaturated omega-3 fatty acids are increasingly proposed as dietary supplements with the ability to reduce the risk of cognitive decline, including Alzheimer's disease (AD).
AIM
To study the effect of omega-3 on cognitive decline through the review of recent observational, interventional, and experimental studies.
METHODS
We conducted a Pubmed, Medline, Cochrane and Embase search for epidemiological and clinical studies in the international literature using combinations of the following keywords: "Alzheimer's disease", "mild cognitive impairment", "cognitive function", "dietary factors", "omega-3 fatty acids", "EPA and DHA".
CONCLUSIONS
Studies have shown the protective role of omega-3 fatty acids in mild cognitive impairment, dementia, and the risk and progression of Alzheimer's disease in the elderly. Further studies are needed to understand the mechanism of action of omega-3 fatty acids on cognition. Doses, composition of EPA and DHA capsules and time of supplementation should be explored.
TY - JOUR
T1 - [Contribution of omega-3 fatty acids for memory and cognitive function].
AU - Waitzberg,Dan L,
AU - Garla,Priscila,
Y1 - 2014/09/01/
PY - 2014/9/21/entrez
PY - 2014/9/23/pubmed
PY - 2016/7/29/medline
SP - 467
EP - 77
JF - Nutricion hospitalaria
JO - Nutr Hosp
VL - 30
IS - 3
N2 - INTRODUCTION: A decline in memory and cognitive function is considered to be a normal consequence of aging. Polyunsaturated omega-3 fatty acids are increasingly proposed as dietary supplements with the ability to reduce the risk of cognitive decline, including Alzheimer's disease (AD). AIM: To study the effect of omega-3 on cognitive decline through the review of recent observational, interventional, and experimental studies. METHODS: We conducted a Pubmed, Medline, Cochrane and Embase search for epidemiological and clinical studies in the international literature using combinations of the following keywords: "Alzheimer's disease", "mild cognitive impairment", "cognitive function", "dietary factors", "omega-3 fatty acids", "EPA and DHA". CONCLUSIONS: Studies have shown the protective role of omega-3 fatty acids in mild cognitive impairment, dementia, and the risk and progression of Alzheimer's disease in the elderly. Further studies are needed to understand the mechanism of action of omega-3 fatty acids on cognition. Doses, composition of EPA and DHA capsules and time of supplementation should be explored.
SN - 1699-5198
UR - https://www.unboundmedicine.com/medline/citation/25238820/[Contribution_of_omega_3_fatty_acids_for_memory_and_cognitive_function]_
DB - PRIME
DP - Unbound Medicine
ER -