Protracted fecal shedding of HEV during ribavirin therapy predicts treatment relapse.Clin Infect Dis. 2015 Jan 01; 60(1):96-9.CI
Twenty-four solid-organ-transplant recipients with chronic hepatitis E virus (HEV) infections were given ribavirin therapy for 3 months. All the patients with protracted fecal HEV shedding during treatment suffered a relapse. Monitoring HEV fecal excretion could be used to determine the optimal duration of ribavirin therapy.