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Impact of Serum Albumin Levels on Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndromes Treated With Percutaneous Coronary Intervention.
Angiology. 2015 Sep; 66(8):732-7.A

Abstract

Patients with acute coronary syndromes (ACSs) undergoing percutaneous coronary intervention (PCI) are at high risk of contrast-induced acute kidney injury (CI-AKI), a complication associated with poor clinical outcomes. Serum albumin (SA) levels are associated with cardiovascular mortality. We assessed the association between SA levels and the risk of CI-AKI in patients with ACS (n = 890) treated with PCI. Patients were divided into 2 groups: patients with and without CI-AKI. Contrast-induced acute kidney injury was defined as an increase in serum creatinine (≥25% or ≥0.5 mg/dL) from baseline occurring 72 hours after PCI. The SA levels were significantly lower in patients with CI-AKI than in those without CI-AKI (3.52 ± 0.40 vs 3.94 ± 0.39 mg/dL, P < .001). On multivariate analysis, SA was an independent predictor of CI-AKI (odds ratio 0.177, 95% confidence interval 0.080-0.392, P < .001) together with age, female gender, creatine kinase-myocardial band, and glomerular filtration rate. Baseline SA levels are inversely associated with CI-AKI after PCI for ACS.

Authors+Show Affiliations

Department of Cardiology, Ankara Education and Research Hospital, Ankara, Turkey sanimurat@gmail.com.Department of Cardiology, Ankara Education and Research Hospital, Ankara, Turkey.Department of Cardiology, Ankara Education and Research Hospital, Ankara, Turkey.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25260710

Citation

Murat, Sani Namik, et al. "Impact of Serum Albumin Levels On Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndromes Treated With Percutaneous Coronary Intervention." Angiology, vol. 66, no. 8, 2015, pp. 732-7.
Murat SN, Kurtul A, Yarlioglues M. Impact of Serum Albumin Levels on Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndromes Treated With Percutaneous Coronary Intervention. Angiology. 2015;66(8):732-7.
Murat, S. N., Kurtul, A., & Yarlioglues, M. (2015). Impact of Serum Albumin Levels on Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndromes Treated With Percutaneous Coronary Intervention. Angiology, 66(8), 732-7. https://doi.org/10.1177/0003319714551979
Murat SN, Kurtul A, Yarlioglues M. Impact of Serum Albumin Levels On Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndromes Treated With Percutaneous Coronary Intervention. Angiology. 2015;66(8):732-7. PubMed PMID: 25260710.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impact of Serum Albumin Levels on Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndromes Treated With Percutaneous Coronary Intervention. AU - Murat,Sani Namik, AU - Kurtul,Alparslan, AU - Yarlioglues,Mikail, Y1 - 2014/09/26/ PY - 2014/9/28/entrez PY - 2014/9/28/pubmed PY - 2015/11/4/medline KW - acute coronary syndromes KW - contrast-induced acute kidney injury KW - percutaneous coronary intervention KW - serum albumin level SP - 732 EP - 7 JF - Angiology JO - Angiology VL - 66 IS - 8 N2 - Patients with acute coronary syndromes (ACSs) undergoing percutaneous coronary intervention (PCI) are at high risk of contrast-induced acute kidney injury (CI-AKI), a complication associated with poor clinical outcomes. Serum albumin (SA) levels are associated with cardiovascular mortality. We assessed the association between SA levels and the risk of CI-AKI in patients with ACS (n = 890) treated with PCI. Patients were divided into 2 groups: patients with and without CI-AKI. Contrast-induced acute kidney injury was defined as an increase in serum creatinine (≥25% or ≥0.5 mg/dL) from baseline occurring 72 hours after PCI. The SA levels were significantly lower in patients with CI-AKI than in those without CI-AKI (3.52 ± 0.40 vs 3.94 ± 0.39 mg/dL, P < .001). On multivariate analysis, SA was an independent predictor of CI-AKI (odds ratio 0.177, 95% confidence interval 0.080-0.392, P < .001) together with age, female gender, creatine kinase-myocardial band, and glomerular filtration rate. Baseline SA levels are inversely associated with CI-AKI after PCI for ACS. SN - 1940-1574 UR - https://www.unboundmedicine.com/medline/citation/25260710/Impact_of_Serum_Albumin_Levels_on_Contrast_Induced_Acute_Kidney_Injury_in_Patients_With_Acute_Coronary_Syndromes_Treated_With_Percutaneous_Coronary_Intervention_ L2 - http://journals.sagepub.com/doi/full/10.1177/0003319714551979?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -