Micronutrient and physiologic parameters before and 6 months after RYGB.
BACKGROUNDBariatric surgery is considered an effective method for sustained weight loss, but may cause various nutritional complications. The aim of this study was to evaluate the nutritional status of minerals and vitamins, food consumption, and to monitor physiologic parameters in patients with obesity before and 6 months after Roux-en-Y gastric bypass surgery (RYGB).
METHODSThirty-six patients who had undergone RYGB were prospectively evaluated before and 6 months after surgery. At each phase their weight, height, body mass index (BMI), Electro Sensor Complex (ES Complex) data, food consumption, and total protein serum levels, albumin, prealbumin, parathyroid hormone (PTH), zinc (Zn), B12 vitamin (VitB12), iron (Fe), ferritin, copper (Cu), ionic calcium (CaI), magnesium (Mg), and folic acid were assessed.
RESULTSThe mean weight loss from baseline to 6 months after surgery was 35.34±4.82%. Markers of autonomic nervous system balance (P<.01), stiffness index (P<.01), standard deviation of normal-to-normal R-R intervals (SDNN) (P<.01), and insulin resistance (P<.001) were also improved. With regard to the micronutrients measured, 34 patients demonstrated some kind of deficiency. There was a high percentage of Zn deficiency in both pre- (55.55%) and postoperative (61.11%) patients, and 33.33% of the patients were deficient in prealbumin postoperatively. The protein intake after 6 months of surgery was below the recommended intake (<70 g/d) for 88.88% of the patients. Laboratory analyses demonstrated an average decrease in total protein (P<.05), prealbumin (P = .002), and PTH (P = .008) between pre- and postsurgery, and a decrease in the percentage of deficiencies for Mg (P<.05), CaI (P<.05), and Fe (P = .021).
CONCLUSIONDespite improvements in the autonomic nervous system balance, stiffness index markers and insulin resistance, we found a high prevalence of hypozincemia at 6 months post-RYGB. Furthermore, protein supplements were needed to maintain an adequate protein intake up to 6 months postsurgery.
Nutricionist Postgraduate in Nutrition in the Digestive System (UNICAMP), Campinas, São Paulo, Brazil; Faculdade de Ciências Médicas- Departamento de Cirurgia do Hospital de Clínicas UNICAMP, Campinas, São Paulo, Brazil. Electronic address: firstname.lastname@example.org.,
Laboratório de Nutrição e Metabolismo- Departamento de Biodinâmica do Movimento Humano-Escola de Educação Física e Esporte - USP, São Paulo, Brazil.
Faculdade de Ciências Médicas- Departamento de Cirurgia do Hospital de Clínicas UNICAMP, Campinas, São Paulo, Brazil.
Autonomic Nervous System
Body Mass Index
Vitamin B 12
Vitamin B Deficiency
Pub Type(s)Journal Article