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Investigating the association between obstructive sleep apnea and periodontitis.
J Periodontol. 2015 Feb; 86(2):232-43.JP

Abstract

BACKGROUND

Obstructive sleep apnea (OSA) is a sleep disorder characterized by disruptions of normal sleep architecture. Chronic periodontitis is a chronic disease of the periodontium that elicits a general inflammatory response to local dental plaque. It has been suggested that periodontal disease may increase in severity with increasingly severe OSA because both disease entities share common inflammatory pathways, acting synergistically to alter the host response. The aim of this study is to analyze the association between severity of OSA and the prevalence/severity of periodontitis.

METHODS

One hundred patients from a large veterans administration sleep study center (n = 26 normal, n = 21 mild, n = 19 moderate, n = 34 severe) diagnosed with an overnight polysomnogram underwent a comprehensive periodontal examination. Periodontal parameters measured included the following: 1) mean periodontal probing depth (PD); 2) clinical attachment level (CAL); 3) gingival recession; and 4) percentage of sites with bleeding on probing, plaque, PD ≥5 mm, and CAL ≥3 mm.

RESULTS

Seventy-three percent of the sampled population had moderate/severe periodontal disease. χ(2) analyses revealed no significant differences in the prevalence of periodontal disease between the apnea-hypopnea index (AHI) groups, with a negligible Spearman correlation coefficient of 0.246 between AHI severity and periodontal disease severity categories. Analysis of covariance indicated a significant association between AHI severity categories and percentage of sites with plaque, after adjusting for age. Multivariable logistic regression analysis predicting moderate/severe periodontitis with AHI score, age, and smoking status indicated a significant association with age (P = 0.028) but no significant association with the other two predictors.

CONCLUSION

OSA was not significantly associated with the prevalence of moderate/severe periodontitis and the periodontal parameters examined, except percentage plaque.

Authors+Show Affiliations

Department of Periodontics, University of Texas Health Science Center at San Antonio Dental School, San Antonio, TX.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

25299385

Citation

Loke, Weiqiang, et al. "Investigating the Association Between Obstructive Sleep Apnea and Periodontitis." Journal of Periodontology, vol. 86, no. 2, 2015, pp. 232-43.
Loke W, Girvan T, Ingmundson P, et al. Investigating the association between obstructive sleep apnea and periodontitis. J Periodontol. 2015;86(2):232-43.
Loke, W., Girvan, T., Ingmundson, P., Verrett, R., Schoolfield, J., & Mealey, B. L. (2015). Investigating the association between obstructive sleep apnea and periodontitis. Journal of Periodontology, 86(2), 232-43. https://doi.org/10.1902/jop.2014.140229
Loke W, et al. Investigating the Association Between Obstructive Sleep Apnea and Periodontitis. J Periodontol. 2015;86(2):232-43. PubMed PMID: 25299385.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Investigating the association between obstructive sleep apnea and periodontitis. AU - Loke,Weiqiang, AU - Girvan,Thomas, AU - Ingmundson,Paul, AU - Verrett,Ronald, AU - Schoolfield,John, AU - Mealey,Brian L, Y1 - 2014/10/09/ PY - 2014/10/10/entrez PY - 2014/10/10/pubmed PY - 2016/4/6/medline KW - Chronic periodontitis KW - sleep apnea, obstructive SP - 232 EP - 43 JF - Journal of periodontology JO - J Periodontol VL - 86 IS - 2 N2 - BACKGROUND: Obstructive sleep apnea (OSA) is a sleep disorder characterized by disruptions of normal sleep architecture. Chronic periodontitis is a chronic disease of the periodontium that elicits a general inflammatory response to local dental plaque. It has been suggested that periodontal disease may increase in severity with increasingly severe OSA because both disease entities share common inflammatory pathways, acting synergistically to alter the host response. The aim of this study is to analyze the association between severity of OSA and the prevalence/severity of periodontitis. METHODS: One hundred patients from a large veterans administration sleep study center (n = 26 normal, n = 21 mild, n = 19 moderate, n = 34 severe) diagnosed with an overnight polysomnogram underwent a comprehensive periodontal examination. Periodontal parameters measured included the following: 1) mean periodontal probing depth (PD); 2) clinical attachment level (CAL); 3) gingival recession; and 4) percentage of sites with bleeding on probing, plaque, PD ≥5 mm, and CAL ≥3 mm. RESULTS: Seventy-three percent of the sampled population had moderate/severe periodontal disease. χ(2) analyses revealed no significant differences in the prevalence of periodontal disease between the apnea-hypopnea index (AHI) groups, with a negligible Spearman correlation coefficient of 0.246 between AHI severity and periodontal disease severity categories. Analysis of covariance indicated a significant association between AHI severity categories and percentage of sites with plaque, after adjusting for age. Multivariable logistic regression analysis predicting moderate/severe periodontitis with AHI score, age, and smoking status indicated a significant association with age (P = 0.028) but no significant association with the other two predictors. CONCLUSION: OSA was not significantly associated with the prevalence of moderate/severe periodontitis and the periodontal parameters examined, except percentage plaque. SN - 1943-3670 UR - https://www.unboundmedicine.com/medline/citation/25299385/Investigating_the_association_between_obstructive_sleep_apnea_and_periodontitis_ L2 - https://doi.org/10.1902/jop.2014.140229 DB - PRIME DP - Unbound Medicine ER -