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Zika virus emergence in mosquitoes in southeastern Senegal, 2011.
PLoS One. 2014; 9(10):e109442.Plos

Abstract

BACKGROUND

Zika virus (ZIKV; genus Flavivirus, family Flaviviridae) is maintained in a zoonotic cycle between arboreal Aedes spp. mosquitoes and nonhuman primates in African and Asian forests. Spillover into humans has been documented in both regions and the virus is currently responsible for a large outbreak in French Polynesia. ZIKV amplifications are frequent in southeastern Senegal but little is known about their seasonal and spatial dynamics. The aim of this paper is to describe the spatio-temporal patterns of the 2011 ZIKV amplification in southeastern Senegal.

METHODOLOGY/FINDINGS

Mosquitoes were collected monthly from April to December 2011 except during July. Each evening from 18:00 to 21:00 hrs landing collections were performed by teams of 3 persons working simultaneously in forest (canopy and ground), savannah, agriculture, village (indoor and outdoor) and barren land cover sites. Mosquitoes were tested for virus infection by virus isolation and RT-PCR. ZIKV was detected in 31 of the 1,700 mosquito pools (11,247 mosquitoes) tested: Ae. furcifer (5), Ae. luteocephalus (5), Ae. africanus (5), Ae. vittatus (3), Ae. taylori, Ae. dalzieli, Ae. hirsutus and Ae. metallicus (2 each) and Ae. aegypti, Ae. unilinaetus, Ma. uniformis, Cx. perfuscus and An. coustani (1 pool each) collected in June (3), September (10), October (11), November (6) and December (1). ZIKV was detected from mosquitoes collected in all land cover classes except indoor locations within villages. The virus was detected in only one of the ten villages investigated.

CONCLUSIONS/SIGNIFICANCE

This ZIKV amplification was widespread in the Kédougou area, involved several mosquito species as probable vectors, and encompassed all investigated land cover classes except indoor locations within villages. Aedes furcifer males and Aedes vittatus were found infected within a village, thus these species are probably involved in the transmission of Zika virus to humans in this environment.

Authors+Show Affiliations

Unité d'Entomologie Médicale, Institut Pasteur de Dakar, Dakar, Sénégal.Unité des Arbovirus et Virus des Fièvres Hémorragiques, Institut Pasteur de Dakar, Dakar, Sénégal.Unité d'Entomologie Médicale, Institut Pasteur de Dakar, Dakar, Sénégal.Unité des Arbovirus et Virus des Fièvres Hémorragiques, Institut Pasteur de Dakar, Dakar, Sénégal.Unité des Arbovirus et Virus des Fièvres Hémorragiques, Institut Pasteur de Dakar, Dakar, Sénégal.Unité d'Entomologie Médicale, Institut Pasteur de Dakar, Dakar, Sénégal.Department of Biology, New Mexico State University, Las Cruces, New Mexico, United States of America.Department of Geography, New Mexico State University, Las Cruces, New Mexico, United States of America.Institute for Human Infections and Immunity, Center for Tropical Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America.Unité d'Entomologie Médicale, Institut Pasteur de Dakar, Dakar, Sénégal.

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

25310102

Citation

Diallo, Diawo, et al. "Zika Virus Emergence in Mosquitoes in Southeastern Senegal, 2011." PloS One, vol. 9, no. 10, 2014, pp. e109442.
Diallo D, Sall AA, Diagne CT, et al. Zika virus emergence in mosquitoes in southeastern Senegal, 2011. PLoS ONE. 2014;9(10):e109442.
Diallo, D., Sall, A. A., Diagne, C. T., Faye, O., Faye, O., Ba, Y., Hanley, K. A., Buenemann, M., Weaver, S. C., & Diallo, M. (2014). Zika virus emergence in mosquitoes in southeastern Senegal, 2011. PloS One, 9(10), e109442. https://doi.org/10.1371/journal.pone.0109442
Diallo D, et al. Zika Virus Emergence in Mosquitoes in Southeastern Senegal, 2011. PLoS ONE. 2014;9(10):e109442. PubMed PMID: 25310102.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zika virus emergence in mosquitoes in southeastern Senegal, 2011. AU - Diallo,Diawo, AU - Sall,Amadou A, AU - Diagne,Cheikh T, AU - Faye,Oumar, AU - Faye,Ousmane, AU - Ba,Yamar, AU - Hanley,Kathryn A, AU - Buenemann,Michaela, AU - Weaver,Scott C, AU - Diallo,Mawlouth, Y1 - 2014/10/13/ PY - 2014/04/11/received PY - 2014/09/04/accepted PY - 2014/10/14/entrez PY - 2014/10/14/pubmed PY - 2015/6/30/medline SP - e109442 EP - e109442 JF - PloS one JO - PLoS ONE VL - 9 IS - 10 N2 - BACKGROUND: Zika virus (ZIKV; genus Flavivirus, family Flaviviridae) is maintained in a zoonotic cycle between arboreal Aedes spp. mosquitoes and nonhuman primates in African and Asian forests. Spillover into humans has been documented in both regions and the virus is currently responsible for a large outbreak in French Polynesia. ZIKV amplifications are frequent in southeastern Senegal but little is known about their seasonal and spatial dynamics. The aim of this paper is to describe the spatio-temporal patterns of the 2011 ZIKV amplification in southeastern Senegal. METHODOLOGY/FINDINGS: Mosquitoes were collected monthly from April to December 2011 except during July. Each evening from 18:00 to 21:00 hrs landing collections were performed by teams of 3 persons working simultaneously in forest (canopy and ground), savannah, agriculture, village (indoor and outdoor) and barren land cover sites. Mosquitoes were tested for virus infection by virus isolation and RT-PCR. ZIKV was detected in 31 of the 1,700 mosquito pools (11,247 mosquitoes) tested: Ae. furcifer (5), Ae. luteocephalus (5), Ae. africanus (5), Ae. vittatus (3), Ae. taylori, Ae. dalzieli, Ae. hirsutus and Ae. metallicus (2 each) and Ae. aegypti, Ae. unilinaetus, Ma. uniformis, Cx. perfuscus and An. coustani (1 pool each) collected in June (3), September (10), October (11), November (6) and December (1). ZIKV was detected from mosquitoes collected in all land cover classes except indoor locations within villages. The virus was detected in only one of the ten villages investigated. CONCLUSIONS/SIGNIFICANCE: This ZIKV amplification was widespread in the Kédougou area, involved several mosquito species as probable vectors, and encompassed all investigated land cover classes except indoor locations within villages. Aedes furcifer males and Aedes vittatus were found infected within a village, thus these species are probably involved in the transmission of Zika virus to humans in this environment. SN - 1932-6203 UR - https://www.unboundmedicine.com/medline/citation/25310102/Zika_virus_emergence_in_mosquitoes_in_southeastern_Senegal_2011_ L2 - http://dx.plos.org/10.1371/journal.pone.0109442 DB - PRIME DP - Unbound Medicine ER -