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Relationships between degree of polymerization and antioxidant activities: a study on proanthocyanidins from the leaves of a medicinal mangrove plant Ceriops tagal.
PLoS One. 2014; 9(10):e107606.Plos

Abstract

Tannins from the leaves of a medicinal mangrove plant, Ceriops tagal, were purified and fractionated on Sephadex LH-20 columns. 13C nuclear magnetic resonance (13C-NMR), reversed/normal high performance liquid chromatography electrospray ionization mass spectrometry (HPLC-ESI MS) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDT-TOF MS) analysis showed that the tannins were predominantly B-type procyanidins with minor A-type linkages, galloyl and glucosyl substitutions, and a degree of polymerization (DP) up to 33. Thirteen subfractions of the procyanidins were successfully obtained by a modified fractionation method, and their antioxidant activities were investigated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging capacity and ferric reducing antioxidant power (FRAP) method. All these subfractions exhibited potent antioxidant activities, and eleven of them showed significantly different mean DP (mDP) ranging from 1.43±0.04 to 31.77±1.15. Regression analysis demonstrated that antioxidant activities were positively correlative with mDP when around mDP <10, while dropped and then remained at a level similar to mDP = 5 with around 95 µg ml(-1) for DPPH scavenging activity and 4 mmol AAE g(-1) for FRAP value.

Authors+Show Affiliations

Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems, Xiamen University, Xiamen, China; Department of Biology and Chemistry, City University of Hong Kong, Hong Kong SAR, China; Futian-CityU Mangrove R&D Centre, City University of Hong Kong Shenzhen Research Institute, Shenzhen, China.Department of Biology and Chemistry, City University of Hong Kong, Hong Kong SAR, China; Futian-CityU Mangrove R&D Centre, City University of Hong Kong Shenzhen Research Institute, Shenzhen, China.Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems, Xiamen University, Xiamen, China.Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems, Xiamen University, Xiamen, China.Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems, Xiamen University, Xiamen, China.Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems, Xiamen University, Xiamen, China.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25313980

Citation

Zhou, Hai-Chao, et al. "Relationships Between Degree of Polymerization and Antioxidant Activities: a Study On Proanthocyanidins From the Leaves of a Medicinal Mangrove Plant Ceriops Tagal." PloS One, vol. 9, no. 10, 2014, pp. e107606.
Zhou HC, Tam NF, Lin YM, et al. Relationships between degree of polymerization and antioxidant activities: a study on proanthocyanidins from the leaves of a medicinal mangrove plant Ceriops tagal. PLoS One. 2014;9(10):e107606.
Zhou, H. C., Tam, N. F., Lin, Y. M., Ding, Z. H., Chai, W. M., & Wei, S. D. (2014). Relationships between degree of polymerization and antioxidant activities: a study on proanthocyanidins from the leaves of a medicinal mangrove plant Ceriops tagal. PloS One, 9(10), e107606. https://doi.org/10.1371/journal.pone.0107606
Zhou HC, et al. Relationships Between Degree of Polymerization and Antioxidant Activities: a Study On Proanthocyanidins From the Leaves of a Medicinal Mangrove Plant Ceriops Tagal. PLoS One. 2014;9(10):e107606. PubMed PMID: 25313980.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationships between degree of polymerization and antioxidant activities: a study on proanthocyanidins from the leaves of a medicinal mangrove plant Ceriops tagal. AU - Zhou,Hai-Chao, AU - Tam,Nora Fung-yee, AU - Lin,Yi-Ming, AU - Ding,Zhen-Hua, AU - Chai,Wei-Ming, AU - Wei,Shu-Dong, Y1 - 2014/10/14/ PY - 2014/04/29/received PY - 2014/08/13/accepted PY - 2014/10/15/entrez PY - 2014/10/15/pubmed PY - 2015/6/17/medline SP - e107606 EP - e107606 JF - PloS one JO - PLoS One VL - 9 IS - 10 N2 - Tannins from the leaves of a medicinal mangrove plant, Ceriops tagal, were purified and fractionated on Sephadex LH-20 columns. 13C nuclear magnetic resonance (13C-NMR), reversed/normal high performance liquid chromatography electrospray ionization mass spectrometry (HPLC-ESI MS) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDT-TOF MS) analysis showed that the tannins were predominantly B-type procyanidins with minor A-type linkages, galloyl and glucosyl substitutions, and a degree of polymerization (DP) up to 33. Thirteen subfractions of the procyanidins were successfully obtained by a modified fractionation method, and their antioxidant activities were investigated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging capacity and ferric reducing antioxidant power (FRAP) method. All these subfractions exhibited potent antioxidant activities, and eleven of them showed significantly different mean DP (mDP) ranging from 1.43±0.04 to 31.77±1.15. Regression analysis demonstrated that antioxidant activities were positively correlative with mDP when around mDP <10, while dropped and then remained at a level similar to mDP = 5 with around 95 µg ml(-1) for DPPH scavenging activity and 4 mmol AAE g(-1) for FRAP value. SN - 1932-6203 UR - https://www.unboundmedicine.com/medline/citation/25313980/Relationships_between_degree_of_polymerization_and_antioxidant_activities:_a_study_on_proanthocyanidins_from_the_leaves_of_a_medicinal_mangrove_plant_Ceriops_tagal_ L2 - https://dx.plos.org/10.1371/journal.pone.0107606 DB - PRIME DP - Unbound Medicine ER -