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The clinical effects of Synsepalum dulcificum: a review.
J Med Food. 2014 Nov; 17(11):1165-9.JM

Abstract

Synsepalum dulcificum or the "miracle fruit" is well known for its taste-modifying ability. The aim of this review was to assess the published medically beneficial as well as potential characteristics of this fruit. A search in three databases, including PubMed, ScienceDirect, and Google Scholar, was made with appropriate keywords. The resulting articles were screened in different stages based on the title, abstract, and content. A total of nine articles were included in this review. This review summarized the findings of previously published studies on the effects of miracle fruit. The main studied characteristic of the fruit was its effect on the taste receptors, resulting in the sweet sensation when substances with acidic content were ingested. This effect was shown to be related to a glycoprotein called "miraculin." Other beneficial characteristics of this fruit were its antioxidant and anticancer abilities that are due to the various amides existing in the miracle fruit. Apart from the above, the other observed effect of this fruit was its antidiabetic effect that was tested in rats. Further studies should be conducted to establish the findings. The miracle fruit can be a healthy additive due to its unique characteristics, including sour taste sensation modification as well as its antioxidant and antidiabetic effects.

Authors+Show Affiliations

1 Faculty of Medicine, MAHSA University, Jalan Imlu Jalan University , Kuala Lumpur, Malaysia .No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

25314134

Citation

Swamy, Kaki B., et al. "The Clinical Effects of Synsepalum Dulcificum: a Review." Journal of Medicinal Food, vol. 17, no. 11, 2014, pp. 1165-9.
Swamy KB, Hadi SA, Sekaran M, et al. The clinical effects of Synsepalum dulcificum: a review. J Med Food. 2014;17(11):1165-9.
Swamy, K. B., Hadi, S. A., Sekaran, M., & Pichika, M. R. (2014). The clinical effects of Synsepalum dulcificum: a review. Journal of Medicinal Food, 17(11), 1165-9. https://doi.org/10.1089/jmf.2013.3084
Swamy KB, et al. The Clinical Effects of Synsepalum Dulcificum: a Review. J Med Food. 2014;17(11):1165-9. PubMed PMID: 25314134.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The clinical effects of Synsepalum dulcificum: a review. AU - Swamy,Kaki B, AU - Hadi,Suwaibah Abd, AU - Sekaran,Muniandy, AU - Pichika,Mallikarjuna Rao, Y1 - 2014/10/14/ PY - 2014/10/15/entrez PY - 2014/10/15/pubmed PY - 2015/6/26/medline KW - anti-cancer activity KW - antioxidant activity KW - antiproliferation KW - in vitro KW - in vivo SP - 1165 EP - 9 JF - Journal of medicinal food JO - J Med Food VL - 17 IS - 11 N2 - Synsepalum dulcificum or the "miracle fruit" is well known for its taste-modifying ability. The aim of this review was to assess the published medically beneficial as well as potential characteristics of this fruit. A search in three databases, including PubMed, ScienceDirect, and Google Scholar, was made with appropriate keywords. The resulting articles were screened in different stages based on the title, abstract, and content. A total of nine articles were included in this review. This review summarized the findings of previously published studies on the effects of miracle fruit. The main studied characteristic of the fruit was its effect on the taste receptors, resulting in the sweet sensation when substances with acidic content were ingested. This effect was shown to be related to a glycoprotein called "miraculin." Other beneficial characteristics of this fruit were its antioxidant and anticancer abilities that are due to the various amides existing in the miracle fruit. Apart from the above, the other observed effect of this fruit was its antidiabetic effect that was tested in rats. Further studies should be conducted to establish the findings. The miracle fruit can be a healthy additive due to its unique characteristics, including sour taste sensation modification as well as its antioxidant and antidiabetic effects. SN - 1557-7600 UR - https://www.unboundmedicine.com/medline/citation/25314134/The_clinical_effects_of_Synsepalum_dulcificum:_a_review_ L2 - https://www.liebertpub.com/doi/10.1089/jmf.2013.3084?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -