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[A case of ophthalmic artery occlusion following injection of hyaluronic acid into the glabellar area].

Abstract

PURPOSE

We report a case of unilateral blindness due to ophthalmic artery occlusion following injection of hyaluronic acid into the glabellar area for facial soft-tissue augmentation.

CASE

A 20-year old woman underwent injection of hyaluronic acid into the glabellar area at an aesthetic plastic clinic. Immediately after injection, she suffered nausea, pain, paralysis of limbs and visual loss in her right eye. Hyaluronidase was instanly injected into the same place, but these symptoms did not improve. She was transferred to our hospital's emergency department. At the first examination, she had no light perception in the right eye and her right pupil was dilated. The fundus examination revealed right central artery occlusion. No significant findings were detected in her head. Eye ball massage, hyperbaric oxygen therapy, and drip infusion of urokinase were conducted, but no improvement resulted. Fluorescein and indocyanine green angiography showed no filling of the right retinal and choroidal arteries. Electroretinogram was completely disappeared. Magnetic resonance angiography could not reveal the obstruction point of the ophthalmic artery.

CONCLUSION

Ophthalmic artery occlusion was believed to have occured after injection of hyaluronic acid into the glabellar area.

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  • Authors

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    Source

    Nippon Ganka Gakkai zasshi 118:9 2014 Sep pg 783-7

    MeSH

    Blindness
    Cosmetic Techniques
    Female
    Humans
    Hyaluronic Acid
    Iatrogenic Disease
    Injections
    Nose
    Ophthalmic Artery
    Young Adult

    Pub Type(s)

    Case Reports
    English Abstract
    Journal Article

    Language

    jpn

    PubMed ID

    25318187

    Citation

    Nonomura, Sakiko, et al. "[A Case of Ophthalmic Artery Occlusion Following Injection of Hyaluronic Acid Into the Glabellar Area]." Nippon Ganka Gakkai Zasshi, vol. 118, no. 9, 2014, pp. 783-7.
    Nonomura S, Oshitari T, Miura G, et al. [A case of ophthalmic artery occlusion following injection of hyaluronic acid into the glabellar area]. Nippon Ganka Gakkai Zasshi. 2014;118(9):783-7.
    Nonomura, S., Oshitari, T., Miura, G., Chiba, A., & Yamamoto, S. (2014). [A case of ophthalmic artery occlusion following injection of hyaluronic acid into the glabellar area]. Nippon Ganka Gakkai Zasshi, 118(9), pp. 783-7.
    Nonomura S, et al. [A Case of Ophthalmic Artery Occlusion Following Injection of Hyaluronic Acid Into the Glabellar Area]. Nippon Ganka Gakkai Zasshi. 2014;118(9):783-7. PubMed PMID: 25318187.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - [A case of ophthalmic artery occlusion following injection of hyaluronic acid into the glabellar area]. AU - Nonomura,Sakiko, AU - Oshitari,Toshiyuki, AU - Miura,Gen, AU - Chiba,Akihiro, AU - Yamamoto,Shuichi, PY - 2014/10/17/entrez PY - 2014/10/17/pubmed PY - 2014/11/11/medline SP - 783 EP - 7 JF - Nippon Ganka Gakkai zasshi JO - Nippon Ganka Gakkai Zasshi VL - 118 IS - 9 N2 - PURPOSE: We report a case of unilateral blindness due to ophthalmic artery occlusion following injection of hyaluronic acid into the glabellar area for facial soft-tissue augmentation. CASE: A 20-year old woman underwent injection of hyaluronic acid into the glabellar area at an aesthetic plastic clinic. Immediately after injection, she suffered nausea, pain, paralysis of limbs and visual loss in her right eye. Hyaluronidase was instanly injected into the same place, but these symptoms did not improve. She was transferred to our hospital's emergency department. At the first examination, she had no light perception in the right eye and her right pupil was dilated. The fundus examination revealed right central artery occlusion. No significant findings were detected in her head. Eye ball massage, hyperbaric oxygen therapy, and drip infusion of urokinase were conducted, but no improvement resulted. Fluorescein and indocyanine green angiography showed no filling of the right retinal and choroidal arteries. Electroretinogram was completely disappeared. Magnetic resonance angiography could not reveal the obstruction point of the ophthalmic artery. CONCLUSION: Ophthalmic artery occlusion was believed to have occured after injection of hyaluronic acid into the glabellar area. SN - 0029-0203 UR - https://www.unboundmedicine.com/medline/citation/25318187/[A_case_of_ophthalmic_artery_occlusion_following_injection_of_hyaluronic_acid_into_the_glabellar_area]_ L2 - http://www.medicalonline.jp/meteo_linkout.php?issn=0029-0203&volume=118&issue=9&spage=783 DB - PRIME DP - Unbound Medicine ER -