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[Luteal function in patients with endometriosis].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1989 Oct; 11(5):344-8.ZY

Abstract

Luteal function was studied in 19 cases with endometriosis, infertility being present in 16 cases. Based on previous menstrual cycles, BBT graphs and cervical mucus scores, serum LH concentrations were measured consecutively for 3 days during peri-ovulatory period to define day of LH peak (D0). Meanwhile, serum estradiol (E2) and progesterone (P) levels were determined in early, mid and late luteal phase. Endometrium biopsies were done on 4th and 12th days after BBT rise in 16 cases and dated according to Noyes' criteria. Six normally cycling women with matched age were served as controls.

RESULTS

Serum LH peaks were detected in all patients and normal subjects. All data were synchronized by D0, and analyzed. In endometriosis group, mean serum P levels in early, mid-luteal phase and total luteal phase (the sum of 3 values) were significantly lower than those in control group. Five cases (26.3%) showed low P levels during mid-luteal and/or total luteal phase. Delayed endometrial maturation was observed in 10 of 16 cases (62.5%). Short luteal phase and/or delayed elevation of BBT were shown in 3 of 14 cases (21.4%). Besides, 10 of 12 cases (83.3%) had at least one abnormality in all 3 parameters and 7 cases (58.3%) had two abnormalities. In conclusion, the incidence of luteal phase defect (LPD) is higher in endometriosis group than that in the controls. The mechanisms of LPD and its relationship with infertility were discussed.

Authors

No affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

2534614

Citation

Ji, H. "[Luteal Function in Patients With Endometriosis]." Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae, vol. 11, no. 5, 1989, pp. 344-8.
Ji H. [Luteal function in patients with endometriosis]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1989;11(5):344-8.
Ji, H. (1989). [Luteal function in patients with endometriosis]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae, 11(5), 344-8.
Ji H. [Luteal Function in Patients With Endometriosis]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1989;11(5):344-8. PubMed PMID: 2534614.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Luteal function in patients with endometriosis]. A1 - Ji,H, PY - 1989/10/1/pubmed PY - 1989/10/1/medline PY - 1989/10/1/entrez SP - 344 EP - 8 JF - Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae JO - Zhongguo Yi Xue Ke Xue Yuan Xue Bao VL - 11 IS - 5 N2 - UNLABELLED: Luteal function was studied in 19 cases with endometriosis, infertility being present in 16 cases. Based on previous menstrual cycles, BBT graphs and cervical mucus scores, serum LH concentrations were measured consecutively for 3 days during peri-ovulatory period to define day of LH peak (D0). Meanwhile, serum estradiol (E2) and progesterone (P) levels were determined in early, mid and late luteal phase. Endometrium biopsies were done on 4th and 12th days after BBT rise in 16 cases and dated according to Noyes' criteria. Six normally cycling women with matched age were served as controls. RESULTS: Serum LH peaks were detected in all patients and normal subjects. All data were synchronized by D0, and analyzed. In endometriosis group, mean serum P levels in early, mid-luteal phase and total luteal phase (the sum of 3 values) were significantly lower than those in control group. Five cases (26.3%) showed low P levels during mid-luteal and/or total luteal phase. Delayed endometrial maturation was observed in 10 of 16 cases (62.5%). Short luteal phase and/or delayed elevation of BBT were shown in 3 of 14 cases (21.4%). Besides, 10 of 12 cases (83.3%) had at least one abnormality in all 3 parameters and 7 cases (58.3%) had two abnormalities. In conclusion, the incidence of luteal phase defect (LPD) is higher in endometriosis group than that in the controls. The mechanisms of LPD and its relationship with infertility were discussed. SN - 1000-503X UR - https://www.unboundmedicine.com/medline/citation/2534614/[Luteal_function_in_patients_with_endometriosis]_ L2 - http://www.diseaseinfosearch.org/result/2537 DB - PRIME DP - Unbound Medicine ER -