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Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis.

Abstract

BACKGROUND

The association between tea intake and risk of oral, pharyngeal, and laryngeal carcinoma is still unclear. The aim of this meta-analysis was to quantify the effect of tea consumption on the incidence of oral, pharyngeal, and laryngeal cancer to provide a better understanding on this issue.

MATERIAL/METHODS

A literature search was conducted before January 2014 in MEDLINE and EMBASE databases. The relative risk (RR) estimates that extracted or calculated from all included studies were combined together. Given the existing heterogeneity in the study design and data source, a random-effects model was obtained.

RESULTS

A total of 20 articles were included in the quantitative synthesis. Fourteen RR estimates (11 from case-control studies and 3 from cohort studies) were pooled together and the result demonstrated that tea consumption reduced the incidence of oral cancer (RR=0.85; 95% CI 0.76-0.96). The summary RR of 4 observational studies (3 case-control studies and 1 cohort study) for pharyngeal cancer was 0.87 (95% CI 0.74-1.04). The association between tea consumption and oral and pharyngeal carcinoma was reported. The summary RR for laryngeal carcinoma was 1.05 (95% CI 0.70-1.57). The Begg's funnel plot and the Egger's test showed no evidence of publication bias.

CONCLUSIONS

Tea consumption was associated with decreased risk of oral cancer, while no association was detected with oral/pharyngeal, pharyngeal, or laryngeal cancer.

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  • Authors+Show Affiliations

    ,

    Department of Clinical Oncology, Qilu Hospital of Shandong University, Jinan, Shandong, China (mainland).

    ,

    Department of Pharmacy, Affiliated Hospital of Taishan Medical College, Tai'an, Shandong, China (mainland).

    ,

    Department of Clinical Oncology, Qilu Hospital of Shandong University, Jinan, Shandong, China (mainland).

    Department of Stomatology, Qilu Hospital of Shandong University, Jinan, Shandong, China (mainland).

    Source

    MeSH

    Case-Control Studies
    Cohort Studies
    Humans
    Incidence
    Laryngeal Neoplasms
    Mouth Neoplasms
    Pharyngeal Neoplasms
    Risk Factors
    Tea

    Pub Type(s)

    Journal Article
    Meta-Analysis

    Language

    eng

    PubMed ID

    25363316

    Citation

    Zhang, Wendong, et al. "Tea Intake and Risk of Oral, Pharyngeal, and Laryngeal Carcinoma: a Meta-analysis." Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, vol. 20, 2014, pp. 2142-50.
    Zhang W, Geng T, Han W, et al. Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis. Med Sci Monit. 2014;20:2142-50.
    Zhang, W., Geng, T., Han, W., & Dou, H. (2014). Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 20, pp. 2142-50. doi:10.12659/MSM.892333.
    Zhang W, et al. Tea Intake and Risk of Oral, Pharyngeal, and Laryngeal Carcinoma: a Meta-analysis. Med Sci Monit. 2014 Nov 3;20:2142-50. PubMed PMID: 25363316.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis. AU - Zhang,Wendong, AU - Geng,Tao, AU - Han,Wenfei, AU - Dou,Huiqin, Y1 - 2014/11/03/ PY - 2014/11/4/entrez PY - 2014/11/5/pubmed PY - 2015/5/30/medline SP - 2142 EP - 50 JF - Medical science monitor : international medical journal of experimental and clinical research JO - Med. Sci. Monit. VL - 20 N2 - BACKGROUND: The association between tea intake and risk of oral, pharyngeal, and laryngeal carcinoma is still unclear. The aim of this meta-analysis was to quantify the effect of tea consumption on the incidence of oral, pharyngeal, and laryngeal cancer to provide a better understanding on this issue. MATERIAL/METHODS: A literature search was conducted before January 2014 in MEDLINE and EMBASE databases. The relative risk (RR) estimates that extracted or calculated from all included studies were combined together. Given the existing heterogeneity in the study design and data source, a random-effects model was obtained. RESULTS: A total of 20 articles were included in the quantitative synthesis. Fourteen RR estimates (11 from case-control studies and 3 from cohort studies) were pooled together and the result demonstrated that tea consumption reduced the incidence of oral cancer (RR=0.85; 95% CI 0.76-0.96). The summary RR of 4 observational studies (3 case-control studies and 1 cohort study) for pharyngeal cancer was 0.87 (95% CI 0.74-1.04). The association between tea consumption and oral and pharyngeal carcinoma was reported. The summary RR for laryngeal carcinoma was 1.05 (95% CI 0.70-1.57). The Begg's funnel plot and the Egger's test showed no evidence of publication bias. CONCLUSIONS: Tea consumption was associated with decreased risk of oral cancer, while no association was detected with oral/pharyngeal, pharyngeal, or laryngeal cancer. SN - 1643-3750 UR - https://www.unboundmedicine.com/medline/citation/25363316/Tea_intake_and_risk_of_oral_pharyngeal_and_laryngeal_carcinoma:_a_meta_analysis_ L2 - https://www.medscimonit.com/download/index/idArt/892333 DB - PRIME DP - Unbound Medicine ER -