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Hemorrhagic Transformation of Scrub Typhus Encephalitis: A Rare Entity.
Clin Neuroradiol. 2015 Dec; 25(4):415-8.CN

Abstract

Central nervous system (CNS) involvement of scrub typhus infection is well known. Most CNS involvement of scrub typhus infection present as meningitis or encephalitis. We report on a patient suffering from hemorrhagic transformation of intracranial lesions caused by Orientia tsutsugamushi. A 53-year-old female farmer who was infected by scrub typhus was treated with doxycycline and recovered from the systemic illness. However, headache persisted. Brain radiologic studies revealed acute intracranial hemorrhage and enhancing lesion, which implied a CNS involvement. Hemorrhagic transformation of encephalitis by scrub typhus is very rare complication and to our best knowledge, this is the first report of hemorrhagic transformation of scrub typhus encephalitis. Clinician should consider the possibility of hemorrhagic transformation of encephalitis in cases of scrub typhus infection.

Authors+Show Affiliations

Department of Neurosurgery, Dankook University College of Medicine, 201 Manghyang-ro Dongnam-gu, 330-715, Cheonan, Chungnam, Republic of Korea.Department of Neurosurgery, Dankook University College of Medicine, 201 Manghyang-ro Dongnam-gu, 330-715, Cheonan, Chungnam, Republic of Korea.Department of Neurosurgery, Dankook University College of Medicine, 201 Manghyang-ro Dongnam-gu, 330-715, Cheonan, Chungnam, Republic of Korea. Department of Radiology, Dankook University College of Medicine, Cheonan, Chungnam, Republic of Korea.Department of Neurosurgery, Dankook University College of Medicine, 201 Manghyang-ro Dongnam-gu, 330-715, Cheonan, Chungnam, Republic of Korea. babyface@dankook.ac.kr.

Pub Type(s)

Case Reports
Letter
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25373351

Citation

Kim, H-C, et al. "Hemorrhagic Transformation of Scrub Typhus Encephalitis: a Rare Entity." Clinical Neuroradiology, vol. 25, no. 4, 2015, pp. 415-8.
Kim HC, Yoon KW, Yoo DS, et al. Hemorrhagic Transformation of Scrub Typhus Encephalitis: A Rare Entity. Clin Neuroradiol. 2015;25(4):415-8.
Kim, H. C., Yoon, K. W., Yoo, D. S., & Cho, C. S. (2015). Hemorrhagic Transformation of Scrub Typhus Encephalitis: A Rare Entity. Clinical Neuroradiology, 25(4), 415-8. https://doi.org/10.1007/s00062-014-0348-9
Kim HC, et al. Hemorrhagic Transformation of Scrub Typhus Encephalitis: a Rare Entity. Clin Neuroradiol. 2015;25(4):415-8. PubMed PMID: 25373351.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hemorrhagic Transformation of Scrub Typhus Encephalitis: A Rare Entity. AU - Kim,H-C, AU - Yoon,K-W, AU - Yoo,D-S, AU - Cho,C-S, Y1 - 2014/11/06/ PY - 2014/05/08/received PY - 2014/09/10/accepted PY - 2014/11/7/entrez PY - 2014/11/7/pubmed PY - 2016/9/15/medline SP - 415 EP - 8 JF - Clinical neuroradiology JO - Clin Neuroradiol VL - 25 IS - 4 N2 - Central nervous system (CNS) involvement of scrub typhus infection is well known. Most CNS involvement of scrub typhus infection present as meningitis or encephalitis. We report on a patient suffering from hemorrhagic transformation of intracranial lesions caused by Orientia tsutsugamushi. A 53-year-old female farmer who was infected by scrub typhus was treated with doxycycline and recovered from the systemic illness. However, headache persisted. Brain radiologic studies revealed acute intracranial hemorrhage and enhancing lesion, which implied a CNS involvement. Hemorrhagic transformation of encephalitis by scrub typhus is very rare complication and to our best knowledge, this is the first report of hemorrhagic transformation of scrub typhus encephalitis. Clinician should consider the possibility of hemorrhagic transformation of encephalitis in cases of scrub typhus infection. SN - 1869-1447 UR - https://www.unboundmedicine.com/medline/citation/25373351/Hemorrhagic_Transformation_of_Scrub_Typhus_Encephalitis:_A_Rare_Entity_ L2 - https://dx.doi.org/10.1007/s00062-014-0348-9 DB - PRIME DP - Unbound Medicine ER -