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The influence of dietary fat on liver fat accumulation.
Nutrients 2014; 6(11):5018-33N

Abstract

Obesity is a known risk factor for the development of non-alcoholic fatty liver disease (NAFLD); however, it has been suggested that dietary fat, both amount and composition, may play a pivotal role in its development, independent of body fatness. Studies that have investigated the role of dietary fat on liver fat accumulation are reasonably sparse. We review here the available work that has investigated the impact of dietary fat: amount, composition and frequency, on liver fat accumulation in human observational and intervention studies. Overall, it would seem that total calorie consumption, rather than dietary fat composition, is an important factor in the development of fatty liver disease in humans.

Authors+Show Affiliations

Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK. charlotte.green@ocdem.ox.ac.uk.Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK. leanne.hodson@ocdem.ox.ac.uk.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

25389901

Citation

Green, Charlotte J., and Leanne Hodson. "The Influence of Dietary Fat On Liver Fat Accumulation." Nutrients, vol. 6, no. 11, 2014, pp. 5018-33.
Green CJ, Hodson L. The influence of dietary fat on liver fat accumulation. Nutrients. 2014;6(11):5018-33.
Green, C. J., & Hodson, L. (2014). The influence of dietary fat on liver fat accumulation. Nutrients, 6(11), pp. 5018-33. doi:10.3390/nu6115018.
Green CJ, Hodson L. The Influence of Dietary Fat On Liver Fat Accumulation. Nutrients. 2014 Nov 10;6(11):5018-33. PubMed PMID: 25389901.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The influence of dietary fat on liver fat accumulation. AU - Green,Charlotte J, AU - Hodson,Leanne, Y1 - 2014/11/10/ PY - 2014/10/08/received PY - 2014/10/23/revised PY - 2014/10/27/accepted PY - 2014/11/13/entrez PY - 2014/11/13/pubmed PY - 2015/7/15/medline SP - 5018 EP - 33 JF - Nutrients JO - Nutrients VL - 6 IS - 11 N2 - Obesity is a known risk factor for the development of non-alcoholic fatty liver disease (NAFLD); however, it has been suggested that dietary fat, both amount and composition, may play a pivotal role in its development, independent of body fatness. Studies that have investigated the role of dietary fat on liver fat accumulation are reasonably sparse. We review here the available work that has investigated the impact of dietary fat: amount, composition and frequency, on liver fat accumulation in human observational and intervention studies. Overall, it would seem that total calorie consumption, rather than dietary fat composition, is an important factor in the development of fatty liver disease in humans. SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/25389901/full_citation L2 - http://www.mdpi.com/resolver?pii=nu6115018 DB - PRIME DP - Unbound Medicine ER -