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Antimicrobial activity of methanolic extracts of Sambucus ebulus and Urtica dioica against clinical isolates of methicillin resistant Staphylococcus aureus.

Abstract

BACKGROUND

Increase in the emergence of drug -resistant pathogens led to the development of natural antimicrobials. In this study the antimicrobial effect of methanolic extracts of Sambucus ebulus and Urtica dioica on 16 skin and wound infections isolates of methicillin resistant S. aureus have been studied.

MATERIAL AND METHODS

Solvent extraction procedure was done using soxhlet apparatus for extracting antimicrobial agents from freeze dried plants. Antibacterial activity was measured using agar well diffusion method.

RESULTS

The MIC of Sambucus ebulus and Urtica dioica extracts against the standard strain of S. aureus ATCC 6538 were determined using the micro dilution method at 15 mg and 20 mg respectively. All the test bacteria were found sensitive to the Sambucus ebulus extract and only one isolate was resistant to Urtica dioica extract.

CONCLUSION

Extracts of Sambucus ebulus and Urtica dioica possess antibacterial potency against MRSA isolates and may be used as a natural antiseptics and antimicrobial agents in medicine.

Authors+Show Affiliations

Department of Biology, Rasht Branch, Islamic Azad University, Rasht, Iran.Department of Veterinary science, Rasht Branch, Islamic Azad University, Rasht, Iran.Department of Biology, University of Guilan , Rasht, Iran.Department of Veterinary science, Rasht Branch, Islamic Azad University, Rasht, Iran.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25395702

Citation

Salehzadeh, Ali, et al. "Antimicrobial Activity of Methanolic Extracts of Sambucus Ebulus and Urtica Dioica Against Clinical Isolates of Methicillin Resistant Staphylococcus Aureus." African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM, vol. 11, no. 5, 2014, pp. 38-40.
Salehzadeh A, Asadpour L, Naeemi AS, et al. Antimicrobial activity of methanolic extracts of Sambucus ebulus and Urtica dioica against clinical isolates of methicillin resistant Staphylococcus aureus. Afr J Tradit Complement Altern Med. 2014;11(5):38-40.
Salehzadeh, A., Asadpour, L., Naeemi, A. S., & Houshmand, E. (2014). Antimicrobial activity of methanolic extracts of Sambucus ebulus and Urtica dioica against clinical isolates of methicillin resistant Staphylococcus aureus. African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM, 11(5), pp. 38-40.
Salehzadeh A, et al. Antimicrobial Activity of Methanolic Extracts of Sambucus Ebulus and Urtica Dioica Against Clinical Isolates of Methicillin Resistant Staphylococcus Aureus. Afr J Tradit Complement Altern Med. 2014;11(5):38-40. PubMed PMID: 25395702.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial activity of methanolic extracts of Sambucus ebulus and Urtica dioica against clinical isolates of methicillin resistant Staphylococcus aureus. AU - Salehzadeh,Ali, AU - Asadpour,Leila, AU - Naeemi,Akram Sadat, AU - Houshmand,Elham, Y1 - 2014/08/23/ PY - 2014/11/15/entrez PY - 2014/11/15/pubmed PY - 2015/6/30/medline KW - (MIC) minimum inhibitory concentration KW - Antimicrobial activity KW - MRSA (Methicillin Resistant S. aureus) KW - S. aureus KW - Sambucus ebulus KW - Urtica dioica SP - 38 EP - 40 JF - African journal of traditional, complementary, and alternative medicines : AJTCAM JO - Afr J Tradit Complement Altern Med VL - 11 IS - 5 N2 - BACKGROUND: Increase in the emergence of drug -resistant pathogens led to the development of natural antimicrobials. In this study the antimicrobial effect of methanolic extracts of Sambucus ebulus and Urtica dioica on 16 skin and wound infections isolates of methicillin resistant S. aureus have been studied. MATERIAL AND METHODS: Solvent extraction procedure was done using soxhlet apparatus for extracting antimicrobial agents from freeze dried plants. Antibacterial activity was measured using agar well diffusion method. RESULTS: The MIC of Sambucus ebulus and Urtica dioica extracts against the standard strain of S. aureus ATCC 6538 were determined using the micro dilution method at 15 mg and 20 mg respectively. All the test bacteria were found sensitive to the Sambucus ebulus extract and only one isolate was resistant to Urtica dioica extract. CONCLUSION: Extracts of Sambucus ebulus and Urtica dioica possess antibacterial potency against MRSA isolates and may be used as a natural antiseptics and antimicrobial agents in medicine. SN - 2505-0044 UR - https://www.unboundmedicine.com/medline/citation/25395702/Antimicrobial_activity_of_methanolic_extracts_of_Sambucus_ebulus_and_Urtica_dioica_against_clinical_isolates_of_methicillin_resistant_Staphylococcus_aureus_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25395702/ DB - PRIME DP - Unbound Medicine ER -