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Pulmonary benign metastasizing leiomyoma: a case report.
Int J Clin Exp Pathol. 2014; 7(10):7072-5.IJ

Abstract

Pulmonary benign metastasizing leiomyoma (PBML) is a rare entity usually occurring in females with history of uterine leiomyoma, and it is preferential to metastasize to the lung and appears as a histopathologic benign tumor of smooth muscle origin. In this article, the clinical and pathological data from 1 patient with PBML were analyzed. Chest CT scan showed that multiple well-defined nodules in the both lobes of the lungs. The tumor cells in the lung were well differentiated, and the pattern of tumor was similar to the original tumor. IHC identified it originated from smooth muscle cells, consistent with the diagnosis of PBML. Positive staining of estrogen and progestogen receptors was detected in both the leiomyoma and the metastasizing lesions. During two years of observation, pulmonary function parameters were within normal limits and there was no evidence of tumor recurrence.

Authors+Show Affiliations

Department of Pathology, Tongji Hospital, Tongji University School of Medicine Shanghai 200065, China.Department of Pathology, Tongji Hospital, Tongji University School of Medicine Shanghai 200065, China.

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25400799

Citation

Fan, Desheng, and Xianghua Yi. "Pulmonary Benign Metastasizing Leiomyoma: a Case Report." International Journal of Clinical and Experimental Pathology, vol. 7, no. 10, 2014, pp. 7072-5.
Fan D, Yi X. Pulmonary benign metastasizing leiomyoma: a case report. Int J Clin Exp Pathol. 2014;7(10):7072-5.
Fan, D., & Yi, X. (2014). Pulmonary benign metastasizing leiomyoma: a case report. International Journal of Clinical and Experimental Pathology, 7(10), 7072-5.
Fan D, Yi X. Pulmonary Benign Metastasizing Leiomyoma: a Case Report. Int J Clin Exp Pathol. 2014;7(10):7072-5. PubMed PMID: 25400799.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pulmonary benign metastasizing leiomyoma: a case report. AU - Fan,Desheng, AU - Yi,Xianghua, Y1 - 2014/09/15/ PY - 2014/08/28/received PY - 2014/09/18/accepted PY - 2014/11/18/entrez PY - 2014/11/18/pubmed PY - 2015/7/15/medline KW - Benign metastasizing leiomyoma KW - leiomyoma of uterus KW - lung KW - metastasis SP - 7072 EP - 5 JF - International journal of clinical and experimental pathology JO - Int J Clin Exp Pathol VL - 7 IS - 10 N2 - Pulmonary benign metastasizing leiomyoma (PBML) is a rare entity usually occurring in females with history of uterine leiomyoma, and it is preferential to metastasize to the lung and appears as a histopathologic benign tumor of smooth muscle origin. In this article, the clinical and pathological data from 1 patient with PBML were analyzed. Chest CT scan showed that multiple well-defined nodules in the both lobes of the lungs. The tumor cells in the lung were well differentiated, and the pattern of tumor was similar to the original tumor. IHC identified it originated from smooth muscle cells, consistent with the diagnosis of PBML. Positive staining of estrogen and progestogen receptors was detected in both the leiomyoma and the metastasizing lesions. During two years of observation, pulmonary function parameters were within normal limits and there was no evidence of tumor recurrence. SN - 1936-2625 UR - https://www.unboundmedicine.com/medline/citation/25400799/Pulmonary_benign_metastasizing_leiomyoma:_a_case_report_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25400799/ DB - PRIME DP - Unbound Medicine ER -