Asymmetric dearomatization of β-naphthols through an amination reaction catalyzed by a chiral phosphoric acid.Angew Chem Int Ed Engl. 2015 Jan 07; 54(2):647-50.AC
Abstract
A highly efficient catalytic asymmetric dearomatization of naphthols by means of an electrophilic amination reaction catalyzed by chiral phosphoric acid is presented. This protocol provides a facile access to functionalized β-naphthalenone compounds with a chiral quaternary carbon center in excellent yields and enantioselectivity (up to 99% yield, up to 96% ee).
Links
Pub Type(s)
Journal Article
Language
eng
PubMed ID
25414091
Citation
Wang, Shou-Guo, et al. "Asymmetric Dearomatization of Β-naphthols Through an Amination Reaction Catalyzed By a Chiral Phosphoric Acid." Angewandte Chemie (International Ed. in English), vol. 54, no. 2, 2015, pp. 647-50.
Wang SG, Yin Q, Zhuo CX, et al. Asymmetric dearomatization of β-naphthols through an amination reaction catalyzed by a chiral phosphoric acid. Angew Chem Int Ed Engl. 2015;54(2):647-50.
Wang, S. G., Yin, Q., Zhuo, C. X., & You, S. L. (2015). Asymmetric dearomatization of β-naphthols through an amination reaction catalyzed by a chiral phosphoric acid. Angewandte Chemie (International Ed. in English), 54(2), 647-50. https://doi.org/10.1002/anie.201409756
Wang SG, et al. Asymmetric Dearomatization of Β-naphthols Through an Amination Reaction Catalyzed By a Chiral Phosphoric Acid. Angew Chem Int Ed Engl. 2015 Jan 7;54(2):647-50. PubMed PMID: 25414091.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Asymmetric dearomatization of β-naphthols through an amination reaction catalyzed by a chiral phosphoric acid.
AU - Wang,Shou-Guo,
AU - Yin,Qin,
AU - Zhuo,Chun-Xiang,
AU - You,Shu-Li,
Y1 - 2014/11/20/
PY - 2014/10/04/received
PY - 2014/11/22/entrez
PY - 2014/11/22/pubmed
PY - 2014/11/22/medline
KW - amination reaction
KW - asymmetric catalysis
KW - dearomatization
KW - naphthol
KW - organocatalysis
SP - 647
EP - 50
JF - Angewandte Chemie (International ed. in English)
JO - Angew Chem Int Ed Engl
VL - 54
IS - 2
N2 - A highly efficient catalytic asymmetric dearomatization of naphthols by means of an electrophilic amination reaction catalyzed by chiral phosphoric acid is presented. This protocol provides a facile access to functionalized β-naphthalenone compounds with a chiral quaternary carbon center in excellent yields and enantioselectivity (up to 99% yield, up to 96% ee).
SN - 1521-3773
UR - https://www.unboundmedicine.com/medline/citation/25414091/Asymmetric_dearomatization_of_��_naphthols_through_an_amination_reaction_catalyzed_by_a_chiral_phosphoric_acid_
DB - PRIME
DP - Unbound Medicine
ER -
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