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Admission hyperglycemia in patients with acute coronary syndrome complicated by cardiogenic shock.
Cardiol J. 2015; 22(3):290-5.CJ

Abstract

BACKGROUND

Many reports shoed that for patients with acute coronary syndrome (ACS) increased admission blood glucose (ABG) level is associated with adverse outcomes. Although scientific reports on this issue are still inconsistent, many recent studies confirm that hyperglycemia is also an unfavorable prognostic factor in patients with ACS complicated by cardiogenic shock (CS). The aim of this study is to determine if hyperglycemia on admission can be a predictor of in-hospital death in patients with ACS complicated by CS.

METHODS

The study population consisted of 40 patients with ACS complicated by CS admitted to the Intensive Cardiac Therapy Clinic from January 2010 to May 2013 and treated with primary percutaneous coronary intervention. A control group was selected among patients with uncomplicated ACS.

RESULTS

Patients with CS had significantly higher levels of ABG (15.4 ± 6.26 vs. 7.97 ± ± 2.28 mmol/L, p < 0.01) in comparison with the control group. There was no statistically significant correlation between the level of glucose on admission and in-hospital mortality. Average ABG in patients who survived and in those who died were respectively 15.42 ± 5.61 vs. 15.40 ± 6.87 mmol/L, p > 0.05. Comparison in groups depending on ABG level and calculations with use of receiver-operating characteristics curves showed no relationship between the level of ABG and patients' deaths.

CONCLUSIONS

Hyperglycemia on admission is a clinical feature of patients with ACS who develop CS, however its prognostic value requires further studies.

Authors+Show Affiliations

Intensive Cardiac Therapy Clinic, Medical University of Lodz Łódź. cparamedikus@gmail.com.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25428733

Citation

Jaśkiewicz, Filip, et al. "Admission Hyperglycemia in Patients With Acute Coronary Syndrome Complicated By Cardiogenic Shock." Cardiology Journal, vol. 22, no. 3, 2015, pp. 290-5.
Jaśkiewicz F, Supeł K, Koniarek W, et al. Admission hyperglycemia in patients with acute coronary syndrome complicated by cardiogenic shock. Cardiol J. 2015;22(3):290-5.
Jaśkiewicz, F., Supeł, K., Koniarek, W., & Zielińska, M. (2015). Admission hyperglycemia in patients with acute coronary syndrome complicated by cardiogenic shock. Cardiology Journal, 22(3), 290-5. https://doi.org/10.5603/CJ.a2014.0087
Jaśkiewicz F, et al. Admission Hyperglycemia in Patients With Acute Coronary Syndrome Complicated By Cardiogenic Shock. Cardiol J. 2015;22(3):290-5. PubMed PMID: 25428733.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Admission hyperglycemia in patients with acute coronary syndrome complicated by cardiogenic shock. AU - Jaśkiewicz,Filip, AU - Supeł,Karolina, AU - Koniarek,Włodzimierz, AU - Zielińska,Marzenna, Y1 - 2014/11/27/ PY - 2014/09/03/received PY - 2014/10/22/accepted PY - 2014/11/28/entrez PY - 2014/11/28/pubmed PY - 2016/9/7/medline SP - 290 EP - 5 JF - Cardiology journal JO - Cardiol J VL - 22 IS - 3 N2 - BACKGROUND: Many reports shoed that for patients with acute coronary syndrome (ACS) increased admission blood glucose (ABG) level is associated with adverse outcomes. Although scientific reports on this issue are still inconsistent, many recent studies confirm that hyperglycemia is also an unfavorable prognostic factor in patients with ACS complicated by cardiogenic shock (CS). The aim of this study is to determine if hyperglycemia on admission can be a predictor of in-hospital death in patients with ACS complicated by CS. METHODS: The study population consisted of 40 patients with ACS complicated by CS admitted to the Intensive Cardiac Therapy Clinic from January 2010 to May 2013 and treated with primary percutaneous coronary intervention. A control group was selected among patients with uncomplicated ACS. RESULTS: Patients with CS had significantly higher levels of ABG (15.4 ± 6.26 vs. 7.97 ± ± 2.28 mmol/L, p < 0.01) in comparison with the control group. There was no statistically significant correlation between the level of glucose on admission and in-hospital mortality. Average ABG in patients who survived and in those who died were respectively 15.42 ± 5.61 vs. 15.40 ± 6.87 mmol/L, p > 0.05. Comparison in groups depending on ABG level and calculations with use of receiver-operating characteristics curves showed no relationship between the level of ABG and patients' deaths. CONCLUSIONS: Hyperglycemia on admission is a clinical feature of patients with ACS who develop CS, however its prognostic value requires further studies. SN - 1897-5593 UR - https://www.unboundmedicine.com/medline/citation/25428733/Admission_hyperglycemia_in_patients_with_acute_coronary_syndrome_complicated_by_cardiogenic_shock_ L2 - http://czasopisma.viamedica.pl/cj/article/view/39414 DB - PRIME DP - Unbound Medicine ER -