Tags

Type your tag names separated by a space and hit enter

Zoonotic potential of Escherichia coli isolates from retail chicken meat products and eggs.
Appl Environ Microbiol. 2015 Feb; 81(3):1177-87.AE

Abstract

Chicken products are suspected as a source of extraintestinal pathogenic Escherichia coli (ExPEC), which causes diseases in humans. The zoonotic risk to humans from chicken-source E. coli is not fully elucidated. To clarify the zoonotic risk posed by ExPEC in chicken products and to fill existing knowledge gaps regarding ExPEC zoonosis, we evaluated the prevalence of ExPEC on shell eggs and compared virulence-associated phenotypes between ExPEC and non-ExPEC isolates from both chicken meat and eggs. The prevalence of ExPEC among egg-source isolates was low, i.e., 5/108 (4.7%). Based on combined genotypic and phenotypic screening results, multiple human and avian pathotypes were represented among the chicken-source ExPEC isolates, including avian-pathogenic E. coli (APEC), uropathogenic E. coli (UPEC), neonatal meningitis E. coli (NMEC), and sepsis-associated E. coli (SEPEC), as well as an undefined ExPEC group, which included isolates with fewer virulence factors than the APEC, UPEC, and NMEC isolates. These findings document a substantial prevalence of human-pathogenic ExPEC-associated genes and phenotypes among E. coli isolates from retail chicken products and identify key virulence traits that could be used for screening.

Authors+Show Affiliations

The Biodesign Institute, Arizona State University, Tempe, Arizona, USA.Veterans Affairs Medical Center and University of Minnesota, Minneapolis, Minnesota, USA.Veterans Affairs Medical Center and University of Minnesota, Minneapolis, Minnesota, USA.The Biodesign Institute, Arizona State University, Tempe, Arizona, USA School of Life Sciences, Arizona State University, Tempe, Arizona, USA.The Biodesign Institute, Arizona State University, Tempe, Arizona, USA melha.mellata@asu.edu.

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

25480753

Citation

Mitchell, Natalie M., et al. "Zoonotic Potential of Escherichia Coli Isolates From Retail Chicken Meat Products and Eggs." Applied and Environmental Microbiology, vol. 81, no. 3, 2015, pp. 1177-87.
Mitchell NM, Johnson JR, Johnston B, et al. Zoonotic potential of Escherichia coli isolates from retail chicken meat products and eggs. Appl Environ Microbiol. 2015;81(3):1177-87.
Mitchell, N. M., Johnson, J. R., Johnston, B., Curtiss, R., & Mellata, M. (2015). Zoonotic potential of Escherichia coli isolates from retail chicken meat products and eggs. Applied and Environmental Microbiology, 81(3), 1177-87. https://doi.org/10.1128/AEM.03524-14
Mitchell NM, et al. Zoonotic Potential of Escherichia Coli Isolates From Retail Chicken Meat Products and Eggs. Appl Environ Microbiol. 2015;81(3):1177-87. PubMed PMID: 25480753.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zoonotic potential of Escherichia coli isolates from retail chicken meat products and eggs. AU - Mitchell,Natalie M, AU - Johnson,James R, AU - Johnston,Brian, AU - Curtiss,Roy,3rd AU - Mellata,Melha, Y1 - 2014/12/05/ PY - 2014/12/7/entrez PY - 2014/12/7/pubmed PY - 2015/9/9/medline SP - 1177 EP - 87 JF - Applied and environmental microbiology JO - Appl Environ Microbiol VL - 81 IS - 3 N2 - Chicken products are suspected as a source of extraintestinal pathogenic Escherichia coli (ExPEC), which causes diseases in humans. The zoonotic risk to humans from chicken-source E. coli is not fully elucidated. To clarify the zoonotic risk posed by ExPEC in chicken products and to fill existing knowledge gaps regarding ExPEC zoonosis, we evaluated the prevalence of ExPEC on shell eggs and compared virulence-associated phenotypes between ExPEC and non-ExPEC isolates from both chicken meat and eggs. The prevalence of ExPEC among egg-source isolates was low, i.e., 5/108 (4.7%). Based on combined genotypic and phenotypic screening results, multiple human and avian pathotypes were represented among the chicken-source ExPEC isolates, including avian-pathogenic E. coli (APEC), uropathogenic E. coli (UPEC), neonatal meningitis E. coli (NMEC), and sepsis-associated E. coli (SEPEC), as well as an undefined ExPEC group, which included isolates with fewer virulence factors than the APEC, UPEC, and NMEC isolates. These findings document a substantial prevalence of human-pathogenic ExPEC-associated genes and phenotypes among E. coli isolates from retail chicken products and identify key virulence traits that could be used for screening. SN - 1098-5336 UR - https://www.unboundmedicine.com/medline/citation/25480753/Zoonotic_potential_of_Escherichia_coli_isolates_from_retail_chicken_meat_products_and_eggs_ L2 - http://aem.asm.org/cgi/pmidlookup?view=long&pmid=25480753 DB - PRIME DP - Unbound Medicine ER -