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Scrub typhus-an emerging entity: a study from a tertiary care hospital in North India.
Indian J Public Health. 2014 Oct-Dec; 58(4):281-3.IJ

Abstract

Scrub typhus is a tropical febrile zoonotic disease caused by Orientia tsutsugamushi of the rickettsial family. These are obligate; intracellular Gram-negative coccobacilli transmitted by the bite of infected mites. It is usually under-diagnosed in India due to its varied and nonspecific clinical presentation, limited awareness, and low index of suspicion among clinicians and lack of diagnostic facilities. This study was planned to monitor the level of scrub typhus-specific antibodies among febrile patients in a tertiary care hospital over a period of 1 year for which a rapid qualitative immunochromatographic assay (Standard Diagnostics, Korea) was introduced for the detection of IgM, IgG and IgA antibodies to O. tsutsugamushi from the serum of suspected febrile patients. A total of 98 out of 772 fever patients (12.69%) tested positive for the presence of antibodies against O. tsutsugamushi. Persistent high-grade fever was the defining characteristic in all the cases with the presence of an eschar in only 10.2% (10/98) of cases. Three patients died during the study period while the rest responded to treatment with doxycycline.

Authors+Show Affiliations

Department of Microbiology, Christian Medical College and Hospital, Ludhiana, Punjab, India.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25491523

Citation

Oberoi, Aroma, and Shereen Rachel Varghese. "Scrub Typhus-an Emerging Entity: a Study From a Tertiary Care Hospital in North India." Indian Journal of Public Health, vol. 58, no. 4, 2014, pp. 281-3.
Oberoi A, Varghese SR. Scrub typhus-an emerging entity: a study from a tertiary care hospital in North India. Indian J Public Health. 2014;58(4):281-3.
Oberoi, A., & Varghese, S. R. (2014). Scrub typhus-an emerging entity: a study from a tertiary care hospital in North India. Indian Journal of Public Health, 58(4), 281-3. https://doi.org/10.4103/0019-557X.146299
Oberoi A, Varghese SR. Scrub Typhus-an Emerging Entity: a Study From a Tertiary Care Hospital in North India. Indian J Public Health. 2014 Oct-Dec;58(4):281-3. PubMed PMID: 25491523.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Scrub typhus-an emerging entity: a study from a tertiary care hospital in North India. AU - Oberoi,Aroma, AU - Varghese,Shereen Rachel, PY - 2014/12/11/entrez PY - 2014/12/11/pubmed PY - 2015/3/5/medline SP - 281 EP - 3 JF - Indian journal of public health JO - Indian J Public Health VL - 58 IS - 4 N2 - Scrub typhus is a tropical febrile zoonotic disease caused by Orientia tsutsugamushi of the rickettsial family. These are obligate; intracellular Gram-negative coccobacilli transmitted by the bite of infected mites. It is usually under-diagnosed in India due to its varied and nonspecific clinical presentation, limited awareness, and low index of suspicion among clinicians and lack of diagnostic facilities. This study was planned to monitor the level of scrub typhus-specific antibodies among febrile patients in a tertiary care hospital over a period of 1 year for which a rapid qualitative immunochromatographic assay (Standard Diagnostics, Korea) was introduced for the detection of IgM, IgG and IgA antibodies to O. tsutsugamushi from the serum of suspected febrile patients. A total of 98 out of 772 fever patients (12.69%) tested positive for the presence of antibodies against O. tsutsugamushi. Persistent high-grade fever was the defining characteristic in all the cases with the presence of an eschar in only 10.2% (10/98) of cases. Three patients died during the study period while the rest responded to treatment with doxycycline. SN - 0019-557X UR - https://www.unboundmedicine.com/medline/citation/25491523/Scrub_typhus_an_emerging_entity:_a_study_from_a_tertiary_care_hospital_in_North_India_ L2 - http://www.ijph.in/article.asp?issn=0019-557X;year=2014;volume=58;issue=4;spage=281;epage=283;aulast=Oberoi DB - PRIME DP - Unbound Medicine ER -