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Diet and physical activity in the prevention of colorectal cancer.
J Natl Compr Canc Netw 2014; 12(12):1721-6JN

Abstract

Diet has been linked to the prevention of colorectal cancer (CRC) and may explain some of the differences in incidence and mortality among various populations. Evidence suggests that a high intake of red and processed meats is associated with an increased risk of CRC. The protective benefits of fiber are unclear, although in some studies fiber is associated with reduced CRC risk. The role of supplements, such as calcium, vitamin D, and folic acid, remains uncertain, and these nutrients cannot be currently recommended for chemoprevention. Obesity and sedentary lifestyle have been associated with an increased risk for colon cancer. Because of the inherent difficulty in studying the effects of specific nutrients, dietary pattern analysis may be a preferable approach to the investigation of the relationship between diet and risk for human diseases. Lifestyle modifications, such as increasing physical activity and consumption of a diet rich in fiber, fruits, vegetables, fish, and poultry and low in red and processed meats, have been advocated for primary prevention of several chronic diseases, and may in fact be beneficial for cancer prevention, particularly CRC.

Authors+Show Affiliations

From Memorial Sloan Kettering Cancer Center, New York, New York.From Memorial Sloan Kettering Cancer Center, New York, New York.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25505213

Citation

Mehta, Mamta, and Moshe Shike. "Diet and Physical Activity in the Prevention of Colorectal Cancer." Journal of the National Comprehensive Cancer Network : JNCCN, vol. 12, no. 12, 2014, pp. 1721-6.
Mehta M, Shike M. Diet and physical activity in the prevention of colorectal cancer. J Natl Compr Canc Netw. 2014;12(12):1721-6.
Mehta, M., & Shike, M. (2014). Diet and physical activity in the prevention of colorectal cancer. Journal of the National Comprehensive Cancer Network : JNCCN, 12(12), pp. 1721-6.
Mehta M, Shike M. Diet and Physical Activity in the Prevention of Colorectal Cancer. J Natl Compr Canc Netw. 2014;12(12):1721-6. PubMed PMID: 25505213.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diet and physical activity in the prevention of colorectal cancer. AU - Mehta,Mamta, AU - Shike,Moshe, PY - 2014/12/16/entrez PY - 2014/12/17/pubmed PY - 2015/8/13/medline SP - 1721 EP - 6 JF - Journal of the National Comprehensive Cancer Network : JNCCN JO - J Natl Compr Canc Netw VL - 12 IS - 12 N2 - Diet has been linked to the prevention of colorectal cancer (CRC) and may explain some of the differences in incidence and mortality among various populations. Evidence suggests that a high intake of red and processed meats is associated with an increased risk of CRC. The protective benefits of fiber are unclear, although in some studies fiber is associated with reduced CRC risk. The role of supplements, such as calcium, vitamin D, and folic acid, remains uncertain, and these nutrients cannot be currently recommended for chemoprevention. Obesity and sedentary lifestyle have been associated with an increased risk for colon cancer. Because of the inherent difficulty in studying the effects of specific nutrients, dietary pattern analysis may be a preferable approach to the investigation of the relationship between diet and risk for human diseases. Lifestyle modifications, such as increasing physical activity and consumption of a diet rich in fiber, fruits, vegetables, fish, and poultry and low in red and processed meats, have been advocated for primary prevention of several chronic diseases, and may in fact be beneficial for cancer prevention, particularly CRC. SN - 1540-1413 UR - https://www.unboundmedicine.com/medline/citation/25505213/Diet_and_physical_activity_in_the_prevention_of_colorectal_cancer_ L2 - https://jnccn.org/doi/10.6004/jnccn.2014.0174 DB - PRIME DP - Unbound Medicine ER -