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Synthesis and characterization of antibacterial carboxymethyl cellulose/ZnO nanocomposite hydrogels.
Int J Biol Macromol. 2015 Mar; 74:136-41.IJ

Abstract

In this study, carboxymethyl cellulose/ZnO nanocomposite hydrogels have been synthesized through the in situ formation of ZnO nanoparticles within swollen carboxymethyl cellulose hydrogels. The formation of ZnO nanoparticles in the hydrogels was confirmed using X-ray diffraction, UV-vis spectroscopy and scanning electron microscopy (SEM) studies. SEM micrographs revealed the formation of ZnO nanoparticles with size range of 10-20 nm within the hydrogel matrix. The prepared nanocomposite hydrogels showed a pH and salt sensitive swelling behavior. The ZnO nanocomposite hydrogels have rather higher swelling in different aqueous solutions in comparison with neat hydrogel. The nanocomposite hydrogels demonstrated antibacterial effects against Escherichia coli and Staphylococcus aureus bacteria. The developed carboxymethyl cellulose/ZnO nanocomposite hydrogels can be used effectively for biomedical application.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Yadollahi M
Research Laboratory of Dendrimers and Nanopolymers, Faculty of Chemistry, University of Tabriz, P.O. Box 51666, Tabriz, Iran.
Gholamali I
Research Laboratory of Dendrimers and Nanopolymers, Faculty of Chemistry, University of Tabriz, P.O. Box 51666, Tabriz, Iran.
Namazi H
Research Laboratory of Dendrimers and Nanopolymers, Faculty of Chemistry, University of Tabriz, P.O. Box 51666, Tabriz, Iran. Electronic address: namazi@tabrizu.ac.ir.
Aghazadeh M
Department of Microbiology, Faculty of Medicine, Tabriz University of Medical Science, Tabriz, Iran.

MeSH

Anti-Bacterial AgentsCarboxymethylcellulose SodiumHydrogelsMicrobial Sensitivity TestsNanocompositesX-Ray DiffractionZinc Oxide

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25524743

Citation

Yadollahi, Mehdi, et al. "Synthesis and Characterization of Antibacterial Carboxymethyl cellulose/ZnO Nanocomposite Hydrogels." International Journal of Biological Macromolecules, vol. 74, 2015, pp. 136-41.
Yadollahi M, Gholamali I, Namazi H, et al. Synthesis and characterization of antibacterial carboxymethyl cellulose/ZnO nanocomposite hydrogels. Int J Biol Macromol. 2015;74:136-41.
Yadollahi, M., Gholamali, I., Namazi, H., & Aghazadeh, M. (2015). Synthesis and characterization of antibacterial carboxymethyl cellulose/ZnO nanocomposite hydrogels. International Journal of Biological Macromolecules, 74, 136-41. https://doi.org/10.1016/j.ijbiomac.2014.11.032
Yadollahi M, et al. Synthesis and Characterization of Antibacterial Carboxymethyl cellulose/ZnO Nanocomposite Hydrogels. Int J Biol Macromol. 2015;74:136-41. PubMed PMID: 25524743.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis and characterization of antibacterial carboxymethyl cellulose/ZnO nanocomposite hydrogels. AU - Yadollahi,Mehdi, AU - Gholamali,Iman, AU - Namazi,Hassan, AU - Aghazadeh,Mohammad, Y1 - 2014/12/15/ PY - 2014/05/05/received PY - 2014/11/13/revised PY - 2014/11/21/accepted PY - 2014/12/20/entrez PY - 2014/12/20/pubmed PY - 2015/12/15/medline KW - Antibacterial KW - Carboxymethylcellulose KW - Hydrogel KW - Nanocomposite KW - Zinc oxide nanopartice SP - 136 EP - 41 JF - International journal of biological macromolecules JO - Int J Biol Macromol VL - 74 N2 - In this study, carboxymethyl cellulose/ZnO nanocomposite hydrogels have been synthesized through the in situ formation of ZnO nanoparticles within swollen carboxymethyl cellulose hydrogels. The formation of ZnO nanoparticles in the hydrogels was confirmed using X-ray diffraction, UV-vis spectroscopy and scanning electron microscopy (SEM) studies. SEM micrographs revealed the formation of ZnO nanoparticles with size range of 10-20 nm within the hydrogel matrix. The prepared nanocomposite hydrogels showed a pH and salt sensitive swelling behavior. The ZnO nanocomposite hydrogels have rather higher swelling in different aqueous solutions in comparison with neat hydrogel. The nanocomposite hydrogels demonstrated antibacterial effects against Escherichia coli and Staphylococcus aureus bacteria. The developed carboxymethyl cellulose/ZnO nanocomposite hydrogels can be used effectively for biomedical application. SN - 1879-0003 UR - https://www.unboundmedicine.com/medline/citation/25524743/Synthesis_and_characterization_of_antibacterial_carboxymethyl_cellulose/ZnO_nanocomposite_hydrogels_ DB - PRIME DP - Unbound Medicine ER -