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Overlap of symptoms of gastroesophageal reflux disease, dyspepsia and irritable bowel syndrome in the general population.
Scand J Gastroenterol. 2015 Feb; 50(2):162-9.SJ

Abstract

INTRODUCTION

Gastroesophageal reflux disease (GERD), functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common functional gastrointestinal conditions with significant impact on the daily lives of individuals. The objective was to investigate the prevalence and overlap of the three conditions in a Western general population.

MATERIAL AND METHODS

A nationwide study of 100,000 individuals 20 years and above, randomly selected in the general population. A web-based questionnaire survey formed the basis of this study. Questions regarding FD and IBS were extracted from the ROME III adult questionnaire. Questions regarding GERD were developed based on the Montreal definition. Prevalence estimates for GERD, FD IBS were calculated in total and for each sex separately and for four age groups. A Venn diagram was constructed, illustrating the overlap between the three conditions.

RESULTS

The overall response rate was 52.2%. The prevalence of GERD, FD and IBS was 11.2%, 7.7% and 10.5%, respectively, and overlap between two or three of these conditions was seen among 6.5% of the respondents. Among individuals meeting the criteria of one or more of the conditions GERD, FD and IBS, 30.7% had overlap between two or all three conditions.

CONCLUSION

GERD, FD and IBS are common conditions in the general population and the overlap between these conditions is also quite common. When diagnosing patients with GERD, FD and IBS, physicians should keep in mind that these patients could be suffering from more than one of these conditions.

Authors+Show Affiliations

Research Unit of General Practice, Institute of Public Health, University of Southern Denmark , Odense , Denmark.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25525975

Citation

Rasmussen, Sanne, et al. "Overlap of Symptoms of Gastroesophageal Reflux Disease, Dyspepsia and Irritable Bowel Syndrome in the General Population." Scandinavian Journal of Gastroenterology, vol. 50, no. 2, 2015, pp. 162-9.
Rasmussen S, Jensen TH, Henriksen SL, et al. Overlap of symptoms of gastroesophageal reflux disease, dyspepsia and irritable bowel syndrome in the general population. Scand J Gastroenterol. 2015;50(2):162-9.
Rasmussen, S., Jensen, T. H., Henriksen, S. L., Haastrup, P. F., Larsen, P. V., Søndergaard, J., & Jarbøl, D. E. (2015). Overlap of symptoms of gastroesophageal reflux disease, dyspepsia and irritable bowel syndrome in the general population. Scandinavian Journal of Gastroenterology, 50(2), 162-9. https://doi.org/10.3109/00365521.2014.983157
Rasmussen S, et al. Overlap of Symptoms of Gastroesophageal Reflux Disease, Dyspepsia and Irritable Bowel Syndrome in the General Population. Scand J Gastroenterol. 2015;50(2):162-9. PubMed PMID: 25525975.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Overlap of symptoms of gastroesophageal reflux disease, dyspepsia and irritable bowel syndrome in the general population. AU - Rasmussen,Sanne, AU - Jensen,Trine Holm, AU - Henriksen,Susanne Lund, AU - Haastrup,Peter Fentz, AU - Larsen,Pia Veldt, AU - Søndergaard,Jens, AU - Jarbøl,Dorte Ejg, Y1 - 2014/12/19/ PY - 2014/12/20/entrez PY - 2014/12/20/pubmed PY - 2015/9/18/medline KW - ROME III KW - functional dyspepsia KW - gastroesophageal reflux disease KW - irritable bowel syndrome KW - overlap KW - population-based study KW - the Montreal definition SP - 162 EP - 9 JF - Scandinavian journal of gastroenterology JO - Scand. J. Gastroenterol. VL - 50 IS - 2 N2 - INTRODUCTION: Gastroesophageal reflux disease (GERD), functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common functional gastrointestinal conditions with significant impact on the daily lives of individuals. The objective was to investigate the prevalence and overlap of the three conditions in a Western general population. MATERIAL AND METHODS: A nationwide study of 100,000 individuals 20 years and above, randomly selected in the general population. A web-based questionnaire survey formed the basis of this study. Questions regarding FD and IBS were extracted from the ROME III adult questionnaire. Questions regarding GERD were developed based on the Montreal definition. Prevalence estimates for GERD, FD IBS were calculated in total and for each sex separately and for four age groups. A Venn diagram was constructed, illustrating the overlap between the three conditions. RESULTS: The overall response rate was 52.2%. The prevalence of GERD, FD and IBS was 11.2%, 7.7% and 10.5%, respectively, and overlap between two or three of these conditions was seen among 6.5% of the respondents. Among individuals meeting the criteria of one or more of the conditions GERD, FD and IBS, 30.7% had overlap between two or all three conditions. CONCLUSION: GERD, FD and IBS are common conditions in the general population and the overlap between these conditions is also quite common. When diagnosing patients with GERD, FD and IBS, physicians should keep in mind that these patients could be suffering from more than one of these conditions. SN - 1502-7708 UR - https://www.unboundmedicine.com/medline/citation/25525975/Overlap_of_symptoms_of_gastroesophageal_reflux_disease_dyspepsia_and_irritable_bowel_syndrome_in_the_general_population_ L2 - http://www.tandfonline.com/doi/full/10.3109/00365521.2014.983157 DB - PRIME DP - Unbound Medicine ER -