TY - JOUR T1 - Clinical, environmental, and serologic surveillance studies of melioidosis in Gabon, 2012-2013. AU - Wiersinga,W Joost, AU - Birnie,Emma, AU - Weehuizen,Tassili A F, AU - Alabi,Abraham S, AU - Huson,Michaëla A M, AU - Huis in 't Veld,Robert A G, AU - Mabala,Harry K, AU - Adzoda,Gregoire K, AU - Raczynski-Henk,Yannick, AU - Esen,Meral, AU - Lell,Bertrand, AU - Kremsner,Peter G, AU - Visser,Caroline E, AU - Wuthiekanun,Vanaporn, AU - Peacock,Sharon J, AU - van der Ende,Arie, AU - Limmathurotsakul,Direk, AU - Grobusch,Martin P, PY - 2014/12/23/entrez PY - 2014/12/23/pubmed PY - 2015/9/12/medline SP - 40 EP - 7 JF - Emerging infectious diseases JO - Emerg Infect Dis VL - 21 IS - 1 N2 - Burkholderia pseudomallei, an environmental gram-negative bacillus, is the causative agent of melioidosis and a bio-threat agent. Reports of B. pseudomallei isolation from soil and animals in East and West Africa suggest that melioidosis might be more widely distributed than previously thought. Because it has been found in equatorial areas with tropical climates, we hypothesized that B. pseudomallei could exist in Gabon. During 2012-2013, we conducted a seroprevalance study in which we set up microbiology facilities at a large clinical referral center and prospectively screened all febrile patients by conducting blood cultures and testing for B. pseudomallei and related species; we also determined whether B. pseudomallei could be isolated from soil. We discovered a novel B. pseudomallei sequence type that caused lethal septic shock and identified B. pseudomallei and B. thailandensis in the environment. Our data suggest that melioidosis is emerging in Central Africa but is unrecognized because of the lack of diagnostic microbiology facilities. SN - 1080-6059 UR - https://www.unboundmedicine.com/medline/citation/25530077/Clinical_environmental_and_serologic_surveillance_studies_of_melioidosis_in_Gabon_2012_2013_ L2 - https://doi.org/10.3201/eid2101.140762 DB - PRIME DP - Unbound Medicine ER -