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[Partial deficiency in 21-hydroxylase in certain forms of hirsutism].
C R Seances Soc Biol Fil. 1989; 183(2):117-21.CR

Abstract

The ACTH test is important when hirsutism occurs in women with a slight 21-hydroxylase deficiency, and normal basal 17-OH Progesterone (17-OH-P/plasma levels). Extensive hormonal assays: LH, FSH, Prolactin, 17 beta-estradiol (E2), Estrone, 17OH-P, Androstenedione, Testosterone, Cortisol (C), Dehydroepiandrosterone-S (DEA-S) were carried out in 36 hirsute women. 13 of these presented hormone levels as found in polycystic ovary syndrome (PCOS), 6 women presented a slight 21-hydroxylase deficiency (increased plasma 17-OH-P and decreased C after ACTH test with significant, p less than 0.01, increase of 17-OH-P/C and 17 women presented idiopathic hirsutism (IH). The hormonal pattern, in the basal condition, is not different in IH or in slight 21-hydroxylase deficiency. The ACTH test is able to differentiate between IH and adrenal hirsutism.

Authors+Show Affiliations

Istituto di Clinica Ostetrica e Ginecologia U. C. S. C., Roma.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

2555033

Citation

Lucisano, A, et al. "[Partial Deficiency in 21-hydroxylase in Certain Forms of Hirsutism]." Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales, vol. 183, no. 2, 1989, pp. 117-21.
Lucisano A, Satta MA, Tripodi R, et al. [Partial deficiency in 21-hydroxylase in certain forms of hirsutism]. C R Seances Soc Biol Fil. 1989;183(2):117-21.
Lucisano, A., Satta, M. A., Tripodi, R., Mobili, L., De Cicco, F., Monaco, F., Dell'Acqua, S., & Roche, J. (1989). [Partial deficiency in 21-hydroxylase in certain forms of hirsutism]. Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales, 183(2), 117-21.
Lucisano A, et al. [Partial Deficiency in 21-hydroxylase in Certain Forms of Hirsutism]. C R Seances Soc Biol Fil. 1989;183(2):117-21. PubMed PMID: 2555033.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Partial deficiency in 21-hydroxylase in certain forms of hirsutism]. AU - Lucisano,A, AU - Satta,M A, AU - Tripodi,R, AU - Mobili,L, AU - De Cicco,F, AU - Monaco,F, AU - Dell'Acqua,S, AU - Roche,J, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez SP - 117 EP - 21 JF - Comptes rendus des seances de la Societe de biologie et de ses filiales JO - C R Seances Soc Biol Fil VL - 183 IS - 2 N2 - The ACTH test is important when hirsutism occurs in women with a slight 21-hydroxylase deficiency, and normal basal 17-OH Progesterone (17-OH-P/plasma levels). Extensive hormonal assays: LH, FSH, Prolactin, 17 beta-estradiol (E2), Estrone, 17OH-P, Androstenedione, Testosterone, Cortisol (C), Dehydroepiandrosterone-S (DEA-S) were carried out in 36 hirsute women. 13 of these presented hormone levels as found in polycystic ovary syndrome (PCOS), 6 women presented a slight 21-hydroxylase deficiency (increased plasma 17-OH-P and decreased C after ACTH test with significant, p less than 0.01, increase of 17-OH-P/C and 17 women presented idiopathic hirsutism (IH). The hormonal pattern, in the basal condition, is not different in IH or in slight 21-hydroxylase deficiency. The ACTH test is able to differentiate between IH and adrenal hirsutism. SN - 0037-9026 UR - https://www.unboundmedicine.com/medline/citation/2555033/[Partial_deficiency_in_21_hydroxylase_in_certain_forms_of_hirsutism]_ DB - PRIME DP - Unbound Medicine ER -