Citation
Sexauer, William P., et al. "Vitamin D Deficiency Is Associated With Pulmonary Dysfunction in Cystic Fibrosis." Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society, vol. 14, no. 4, 2015, pp. 497-506.
Sexauer WP, Hadeh A, Ohman-Strickland PA, et al. Vitamin D deficiency is associated with pulmonary dysfunction in cystic fibrosis. J Cyst Fibros. 2015;14(4):497-506.
Sexauer, W. P., Hadeh, A., Ohman-Strickland, P. A., Zanni, R. L., Varlotta, L., Holsclaw, D., Fiel, S., Graff, G. R., Atlas, A., Bisberg, D., Hadjiliadis, D., Michel, S. H., Mintz, D., Chakraborty, R., Marra, B., Lomas, P., Ward, T., Sassman, M., Imbesi, G. C., ... Mallowe, A. M. (2015). Vitamin D deficiency is associated with pulmonary dysfunction in cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society, 14(4), 497-506. https://doi.org/10.1016/j.jcf.2014.12.006
Sexauer WP, et al. Vitamin D Deficiency Is Associated With Pulmonary Dysfunction in Cystic Fibrosis. J Cyst Fibros. 2015;14(4):497-506. PubMed PMID: 25577127.
TY - JOUR
T1 - Vitamin D deficiency is associated with pulmonary dysfunction in cystic fibrosis.
AU - Sexauer,William P,
AU - Hadeh,Anas,
AU - Ohman-Strickland,Pamela A,
AU - Zanni,Robert L,
AU - Varlotta,Laurie,
AU - Holsclaw,Douglas,
AU - Fiel,Stanley,
AU - Graff,Gavin R,
AU - Atlas,Arthur,
AU - Bisberg,Dorothy,
AU - Hadjiliadis,Denis,
AU - Michel,Suzanne H,
AU - Mintz,Daria,
AU - Chakraborty,Rebanta,
AU - Marra,Bridget,
AU - Lomas,Paula,
AU - Ward,Tara,
AU - Sassman,Meagen,
AU - Imbesi,Giovanna C,
AU - Kitch,Diane M,
AU - Mallowe,Allison M,
Y1 - 2015/01/07/
PY - 2014/09/19/received
PY - 2014/12/05/revised
PY - 2014/12/11/accepted
PY - 2015/1/12/entrez
PY - 2015/1/13/pubmed
PY - 2016/4/2/medline
KW - Cystic fibrosis
KW - Lung function
KW - Pulmonary function
KW - Vitamin D
SP - 497
EP - 506
JF - Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
JO - J Cyst Fibros
VL - 14
IS - 4
N2 - BACKGROUND: Vitamin D deficiency is common in CF. Whether vitamin D affects pulmonary function in CF is unknown. METHODS: Data were abstracted from clinically stable CF patients who had pulmonary function studies and serum 25-hydroxyvitamin D [25(OH)D, ng/ml] levels drawn within 2 months of each other. Findings were adjusted for multiple variables known to affect pulmonary function in CF. RESULTS: Enrollees totaled 597. Overall mean 25(OH)D level was 29.6±12.8 ng/ml (SD). Serum 25(OH)D levels showed a significant correlation with forced expiratory volume in 1s (FEV1) % predicted (r=0.20, p<0.0001) and forced vital capacity % predicted (r=0.13, p=0.0019). Multivariate analysis revealed that serum 25(OH)D remained an independent predictor of FEV1 % predicted even after controlling for multiple other factors known to affect CF lung function. CONCLUSIONS: Serum 25(OH)D levels are significantly associated with pulmonary function in CF. Further study is required to determine whether this association is causal.
SN - 1873-5010
UR - https://www.unboundmedicine.com/medline/citation/25577127/full_citation
L2 - https://linkinghub.elsevier.com/retrieve/pii/S1569-1993(14)00303-8
DB - PRIME
DP - Unbound Medicine
ER -