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Noroviruses: epidemiology, immunity and prospects for prevention.
Future Microbiol. 2015; 10(1):53-67.FM

Abstract

In recent years, noroviruses have become recognized as an important cause of both sporadic and epidemic acute gastroenteritis (AGE), largely due to the improved availability of broadly reactive real-time RT-PCR (TaqMan-based RT-PCR) assays. While there is substantial diversity among noroviruses, one specific genotype, GII.4, is the most common etiology in sporadic and epidemic AGE. Outbreaks of norovirus AGE most commonly occur in healthcare facilities and restaurants and result in significant morbidity and mortality and substantial healthcare costs. Norovirus vaccine development is progressing, and Phase I and II human trials have shown proof-of-principle that norovirus vaccines can reduce illness and infection.

Authors+Show Affiliations

Division of Viral Diseases, National Center for Immunization & Respiratory Diseases, Centers for Disease Control & Prevention, 1600 Clifton Road, Mailstop A-34, Atlanta, GA, 30333, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

25598337

Citation

Pringle, Kimberly, et al. "Noroviruses: Epidemiology, Immunity and Prospects for Prevention." Future Microbiology, vol. 10, no. 1, 2015, pp. 53-67.
Pringle K, Lopman B, Vega E, et al. Noroviruses: epidemiology, immunity and prospects for prevention. Future Microbiol. 2015;10(1):53-67.
Pringle, K., Lopman, B., Vega, E., Vinje, J., Parashar, U. D., & Hall, A. J. (2015). Noroviruses: epidemiology, immunity and prospects for prevention. Future Microbiology, 10(1), 53-67. https://doi.org/10.2217/fmb.14.102
Pringle K, et al. Noroviruses: Epidemiology, Immunity and Prospects for Prevention. Future Microbiol. 2015;10(1):53-67. PubMed PMID: 25598337.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Noroviruses: epidemiology, immunity and prospects for prevention. AU - Pringle,Kimberly, AU - Lopman,Benjamin, AU - Vega,Everardo, AU - Vinje,Jan, AU - Parashar,Umesh D, AU - Hall,Aron J, PY - 2015/1/20/entrez PY - 2015/1/20/pubmed PY - 2015/8/11/medline KW - Caliciviridae KW - GII.4 KW - herd immunity KW - norovirus KW - vaccine SP - 53 EP - 67 JF - Future microbiology JO - Future Microbiol VL - 10 IS - 1 N2 - In recent years, noroviruses have become recognized as an important cause of both sporadic and epidemic acute gastroenteritis (AGE), largely due to the improved availability of broadly reactive real-time RT-PCR (TaqMan-based RT-PCR) assays. While there is substantial diversity among noroviruses, one specific genotype, GII.4, is the most common etiology in sporadic and epidemic AGE. Outbreaks of norovirus AGE most commonly occur in healthcare facilities and restaurants and result in significant morbidity and mortality and substantial healthcare costs. Norovirus vaccine development is progressing, and Phase I and II human trials have shown proof-of-principle that norovirus vaccines can reduce illness and infection. SN - 1746-0921 UR - https://www.unboundmedicine.com/medline/citation/25598337/Noroviruses:_epidemiology_immunity_and_prospects_for_prevention_ L2 - https://www.futuremedicine.com/doi/10.2217/fmb.14.102?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -