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Coexistence of endometrioid adenocarcinoma in atypical polypoid adenomyoma.
Kobe J Med Sci. 2014 Dec 04; 60(3):E74-7.KJ

Abstract

Atypical polypoid adenomyoma (APA) is a rare polypoid tumor of the uterus composed of atypical endometrial glands and smooth muscle cells. Concomitant development of endometrial adenocarcinoma in APA remains infrequent. We report a case of the coexistence of endometrioid adenocarcinoma in APA. A 41-year-old patient presented with abnormal genital bleeding. A polypoid mass was extruded from the external cervical os. She underwent transcervical resection of the polypoid mass arising from the lower uterine segment. Pathological examination revealed APA with the foci of well-differentiated endometrioid adenocarcinoma. Subsequently, she underwent total hysterectomy and bilateral salpingo-oophorectomy. No residual malignant lesions were found. Awareness of the close association of APA with the development of endometrial cancer is warranted. A meticulous pathological evaluation of specimen of APA is necessary for the detection of the coexistence of endometrial cancer.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Sanda Municipal Hospital, Sanda, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

25612673

Citation

Sonoyama, Ayako, et al. "Coexistence of Endometrioid Adenocarcinoma in Atypical Polypoid Adenomyoma." The Kobe Journal of Medical Sciences, vol. 60, no. 3, 2014, pp. E74-7.
Sonoyama A, Kanda M, Ojima Y, et al. Coexistence of endometrioid adenocarcinoma in atypical polypoid adenomyoma. Kobe J Med Sci. 2014;60(3):E74-7.
Sonoyama, A., Kanda, M., Ojima, Y., Kizaki, T., & Ohara, N. (2014). Coexistence of endometrioid adenocarcinoma in atypical polypoid adenomyoma. The Kobe Journal of Medical Sciences, 60(3), E74-7.
Sonoyama A, et al. Coexistence of Endometrioid Adenocarcinoma in Atypical Polypoid Adenomyoma. Kobe J Med Sci. 2014 Dec 4;60(3):E74-7. PubMed PMID: 25612673.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coexistence of endometrioid adenocarcinoma in atypical polypoid adenomyoma. AU - Sonoyama,Ayako, AU - Kanda,Masatoshi, AU - Ojima,Yojiro, AU - Kizaki,Tomohiko, AU - Ohara,Noriyuki, Y1 - 2014/12/04/ PY - 2015/1/24/entrez PY - 2015/1/24/pubmed PY - 2015/10/16/medline KW - atypical polypoid adenomyoma KW - endometrial adenocarcinoma SP - E74 EP - 7 JF - The Kobe journal of medical sciences JO - Kobe J Med Sci VL - 60 IS - 3 N2 - Atypical polypoid adenomyoma (APA) is a rare polypoid tumor of the uterus composed of atypical endometrial glands and smooth muscle cells. Concomitant development of endometrial adenocarcinoma in APA remains infrequent. We report a case of the coexistence of endometrioid adenocarcinoma in APA. A 41-year-old patient presented with abnormal genital bleeding. A polypoid mass was extruded from the external cervical os. She underwent transcervical resection of the polypoid mass arising from the lower uterine segment. Pathological examination revealed APA with the foci of well-differentiated endometrioid adenocarcinoma. Subsequently, she underwent total hysterectomy and bilateral salpingo-oophorectomy. No residual malignant lesions were found. Awareness of the close association of APA with the development of endometrial cancer is warranted. A meticulous pathological evaluation of specimen of APA is necessary for the detection of the coexistence of endometrial cancer. SN - 1883-0498 UR - https://www.unboundmedicine.com/medline/citation/25612673/Coexistence_of_endometrioid_adenocarcinoma_in_atypical_polypoid_adenomyoma_ L2 - http://www.med.kobe-u.ac.jp/journal/contents/60/E74.pdf DB - PRIME DP - Unbound Medicine ER -