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Topical anti-inflammatory agents for seborrheic dermatitis of the face or scalp: summary of a Cochrane Review.
JAMA Dermatol. 2015 Feb; 151(2):221-2.JD

Abstract

CLINICAL QUESTION

Are there differences in effectiveness between topical anti-inflammatory treatments (steroids, calcineurin inhibitors, or lithium salts) and placebo or azoles in the treatment of seborrheic dermatitis of the face and scalp in adults?

BOTTOM LINE

The topical anti-inflammatory treatments were more effective in achieving total clearance of symptoms than placebo by 1.4-fold to 8.5-fold, but there are no considerable differences in the anti-inflammatory topical treatments or in comparison with azoles for short-term treatment. There is no evidence of treatment effects in long-term, continuous, or intermittent use of these compounds despite the chronic nature of the disease.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Kastarinen H
Social Insurance Institute of Finland, Regional Office for Eastern Finland, Kuopio, Finland.
Okokon EO
Department of Community Medicine, University of Calabar Teaching Hospital, Calabar, Nigeria.
Verbeek JH
Cochrane Occupational Safety and Health Review Group, Finnish Institute of Occupational Health, Kuopio, Finland.

MeSH

Anti-Inflammatory AgentsDermatitis, SeborrheicDermatologic AgentsFacial DermatosesHumansScalp Dermatoses

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Comment

Language

eng

PubMed ID

25629391

Citation

Kastarinen, Helena, et al. "Topical Anti-inflammatory Agents for Seborrheic Dermatitis of the Face or Scalp: Summary of a Cochrane Review." JAMA Dermatology, vol. 151, no. 2, 2015, pp. 221-2.
Kastarinen H, Okokon EO, Verbeek JH. Topical anti-inflammatory agents for seborrheic dermatitis of the face or scalp: summary of a Cochrane Review. JAMA Dermatol. 2015;151(2):221-2.
Kastarinen, H., Okokon, E. O., & Verbeek, J. H. (2015). Topical anti-inflammatory agents for seborrheic dermatitis of the face or scalp: summary of a Cochrane Review. JAMA Dermatology, 151(2), 221-2. https://doi.org/10.1001/jamadermatol.2014.3186
Kastarinen H, Okokon EO, Verbeek JH. Topical Anti-inflammatory Agents for Seborrheic Dermatitis of the Face or Scalp: Summary of a Cochrane Review. JAMA Dermatol. 2015;151(2):221-2. PubMed PMID: 25629391.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Topical anti-inflammatory agents for seborrheic dermatitis of the face or scalp: summary of a Cochrane Review. AU - Kastarinen,Helena, AU - Okokon,Enembe O, AU - Verbeek,Jos H, PY - 2015/1/29/entrez PY - 2015/1/30/pubmed PY - 2015/10/6/medline SP - 221 EP - 2 JF - JAMA dermatology JO - JAMA Dermatol VL - 151 IS - 2 N2 - CLINICAL QUESTION: Are there differences in effectiveness between topical anti-inflammatory treatments (steroids, calcineurin inhibitors, or lithium salts) and placebo or azoles in the treatment of seborrheic dermatitis of the face and scalp in adults? BOTTOM LINE: The topical anti-inflammatory treatments were more effective in achieving total clearance of symptoms than placebo by 1.4-fold to 8.5-fold, but there are no considerable differences in the anti-inflammatory topical treatments or in comparison with azoles for short-term treatment. There is no evidence of treatment effects in long-term, continuous, or intermittent use of these compounds despite the chronic nature of the disease. SN - 2168-6084 UR - https://www.unboundmedicine.com/medline/citation/25629391/Topical_anti_inflammatory_agents_for_seborrheic_dermatitis_of_the_face_or_scalp:_summary_of_a_Cochrane_Review_ DB - PRIME DP - Unbound Medicine ER -