Tags

Type your tag names separated by a space and hit enter

ICU survivors show no decline in health-related quality of life after 5 years.
Intensive Care Med. 2015 Mar; 41(3):495-504.IC

Abstract

PURPOSE

Severe critical illness requiring treatment in the intensive care unit (ICU) may have a serious impact on patients and their families. However, optimal follow-up periods are not defined and data on health-related quality of life (HRQOL) before ICU admission as well as those beyond 2 years follow-up are limited. The aim of our study was to assess the impact of ICU stay up to 5 years after ICU discharge.

METHODS

We performed a long-term prospective cohort study in patients admitted for longer than 48 h in a medical-surgical ICU. The Short-Form 36 was used to evaluate HRQOL before admission (by proxy within 48 h after admission of the patient), at ICU discharge, and at 1, 2, and 5 years following ICU discharge (all by patients). Changes in HRQOL were assessed using linear mixed modeling.

RESULTS

We included a total of 749 patients (from 2000 to 2007). At 5 years after ICU discharge 234 patients could be evaluated. After correction for natural decline in HRQOL, the mean scores of four dimensions-physical functioning (p < 0.001), role-physical (p < 0.001), general health (p < 0.001), and social functioning (p = 0.003)-were still significantly lower 5 years after ICU discharge compared with their pre-admission levels, although effect sizes were small (<0.5).

CONCLUSIONS

After correction for natural decline, the effect sizes of decreases in HRQOL were small, suggesting that patients regain their age-specific HRQOL 5 years after their ICU stay.

Authors+Show Affiliations

Department of Intensive Care, Gelre Ziekenhuizen Hospital, Albert Schweitzerlaan 31, 7334 DZ, Apeldoorn, The Netherlands, j.hofhuis@gelre.nl.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25672277

Citation

Hofhuis, José G M., et al. "ICU Survivors Show No Decline in Health-related Quality of Life After 5 Years." Intensive Care Medicine, vol. 41, no. 3, 2015, pp. 495-504.
Hofhuis JG, van Stel HF, Schrijvers AJ, et al. ICU survivors show no decline in health-related quality of life after 5 years. Intensive Care Med. 2015;41(3):495-504.
Hofhuis, J. G., van Stel, H. F., Schrijvers, A. J., Rommes, J. H., & Spronk, P. E. (2015). ICU survivors show no decline in health-related quality of life after 5 years. Intensive Care Medicine, 41(3), 495-504. https://doi.org/10.1007/s00134-015-3669-5
Hofhuis JG, et al. ICU Survivors Show No Decline in Health-related Quality of Life After 5 Years. Intensive Care Med. 2015;41(3):495-504. PubMed PMID: 25672277.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - ICU survivors show no decline in health-related quality of life after 5 years. AU - Hofhuis,José G M, AU - van Stel,Henk F, AU - Schrijvers,Augustinus J P, AU - Rommes,Johannes H, AU - Spronk,Peter E, Y1 - 2015/02/12/ PY - 2014/10/08/received PY - 2015/01/15/accepted PY - 2015/2/13/entrez PY - 2015/2/13/pubmed PY - 2016/6/10/medline SP - 495 EP - 504 JF - Intensive care medicine JO - Intensive Care Med VL - 41 IS - 3 N2 - PURPOSE: Severe critical illness requiring treatment in the intensive care unit (ICU) may have a serious impact on patients and their families. However, optimal follow-up periods are not defined and data on health-related quality of life (HRQOL) before ICU admission as well as those beyond 2 years follow-up are limited. The aim of our study was to assess the impact of ICU stay up to 5 years after ICU discharge. METHODS: We performed a long-term prospective cohort study in patients admitted for longer than 48 h in a medical-surgical ICU. The Short-Form 36 was used to evaluate HRQOL before admission (by proxy within 48 h after admission of the patient), at ICU discharge, and at 1, 2, and 5 years following ICU discharge (all by patients). Changes in HRQOL were assessed using linear mixed modeling. RESULTS: We included a total of 749 patients (from 2000 to 2007). At 5 years after ICU discharge 234 patients could be evaluated. After correction for natural decline in HRQOL, the mean scores of four dimensions-physical functioning (p < 0.001), role-physical (p < 0.001), general health (p < 0.001), and social functioning (p = 0.003)-were still significantly lower 5 years after ICU discharge compared with their pre-admission levels, although effect sizes were small (<0.5). CONCLUSIONS: After correction for natural decline, the effect sizes of decreases in HRQOL were small, suggesting that patients regain their age-specific HRQOL 5 years after their ICU stay. SN - 1432-1238 UR - https://www.unboundmedicine.com/medline/citation/25672277/ICU_survivors_show_no_decline_in_health_related_quality_of_life_after_5_years_ L2 - https://dx.doi.org/10.1007/s00134-015-3669-5 DB - PRIME DP - Unbound Medicine ER -