Tags

Type your tag names separated by a space and hit enter

Long-lived charge carriers in Mn-doped CdS quantum dots for photoelectrochemical cytosensing.
Chemistry. 2015 Mar 23; 21(13):5129-35.C

Abstract

Photoelectrochemical (PEC) biosensing with semiconductor quantum dots (QDs) has received great attention because it integrates the advantages of both photo-excitation and electrochemical detection. During the photon-to-electricity conversion in PEC processes, electron-hole (charge) separation competes with electron-hole recombination, and the net effect essentially determines the performance of PEC biosensors. Herein, we propose a new approach for slowing down electron-hole recombination to increase charge separation efficiency for PEC biosensor development. Through doping with Mn(2+) , a pair of d bands ((4) T1 and (6) A1) is inserted between the conduction and valence bands of CdS QDs, which alters the electron-hole separation and recombination dynamics, allowing the generation of long-lived charge carriers with ms-scale lifetime that decay about 10(4) -10(5) -fold more slowly than in the case of undoped QDs. Photocurrent tests indicated that Mn(2+) doping resulted in an approximately 80 % increase in photocurrent generation compared with undoped CdS QDs. For application, the Mn-doped CdS QDs were coated on the surface of a glassy carbon electrode and functionalized with a cell surface carbohydrate-specific ligand (3-aminophenylboronic acid). In this way, a sensitive cytosensor for K562 leukemia cells was constructed. Moreover, the sugar-specific binding property of 3-aminophenylboronic acid allowed the electrode to serve as a switch for the capture and release of cells. This has been further explored with a view to developing a reusable PEC cytosensing platform.

Authors+Show Affiliations

State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093 (China); Analytical & Testing Center, Sichuan University, Chengdu 610064 (China).No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25678041

Citation

Wu, Peng, et al. "Long-lived Charge Carriers in Mn-doped CdS Quantum Dots for Photoelectrochemical Cytosensing." Chemistry (Weinheim an Der Bergstrasse, Germany), vol. 21, no. 13, 2015, pp. 5129-35.
Wu P, Pan JB, Li XL, et al. Long-lived charge carriers in Mn-doped CdS quantum dots for photoelectrochemical cytosensing. Chemistry. 2015;21(13):5129-35.
Wu, P., Pan, J. B., Li, X. L., Hou, X., Xu, J. J., & Chen, H. Y. (2015). Long-lived charge carriers in Mn-doped CdS quantum dots for photoelectrochemical cytosensing. Chemistry (Weinheim an Der Bergstrasse, Germany), 21(13), 5129-35. https://doi.org/10.1002/chem.201405798
Wu P, et al. Long-lived Charge Carriers in Mn-doped CdS Quantum Dots for Photoelectrochemical Cytosensing. Chemistry. 2015 Mar 23;21(13):5129-35. PubMed PMID: 25678041.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-lived charge carriers in Mn-doped CdS quantum dots for photoelectrochemical cytosensing. AU - Wu,Peng, AU - Pan,Jian-Bing, AU - Li,Xiang-Ling, AU - Hou,Xiandeng, AU - Xu,Jing-Juan, AU - Chen,Hong-Yuan, Y1 - 2015/02/12/ PY - 2014/10/23/received PY - 2015/2/14/entrez PY - 2015/2/14/pubmed PY - 2016/2/11/medline KW - Mn2+ doping KW - long-lived charge carriers KW - photoelectrochemical biosensing KW - quantum dots KW - sensors SP - 5129 EP - 35 JF - Chemistry (Weinheim an der Bergstrasse, Germany) JO - Chemistry VL - 21 IS - 13 N2 - Photoelectrochemical (PEC) biosensing with semiconductor quantum dots (QDs) has received great attention because it integrates the advantages of both photo-excitation and electrochemical detection. During the photon-to-electricity conversion in PEC processes, electron-hole (charge) separation competes with electron-hole recombination, and the net effect essentially determines the performance of PEC biosensors. Herein, we propose a new approach for slowing down electron-hole recombination to increase charge separation efficiency for PEC biosensor development. Through doping with Mn(2+) , a pair of d bands ((4) T1 and (6) A1) is inserted between the conduction and valence bands of CdS QDs, which alters the electron-hole separation and recombination dynamics, allowing the generation of long-lived charge carriers with ms-scale lifetime that decay about 10(4) -10(5) -fold more slowly than in the case of undoped QDs. Photocurrent tests indicated that Mn(2+) doping resulted in an approximately 80 % increase in photocurrent generation compared with undoped CdS QDs. For application, the Mn-doped CdS QDs were coated on the surface of a glassy carbon electrode and functionalized with a cell surface carbohydrate-specific ligand (3-aminophenylboronic acid). In this way, a sensitive cytosensor for K562 leukemia cells was constructed. Moreover, the sugar-specific binding property of 3-aminophenylboronic acid allowed the electrode to serve as a switch for the capture and release of cells. This has been further explored with a view to developing a reusable PEC cytosensing platform. SN - 1521-3765 UR - https://www.unboundmedicine.com/medline/citation/25678041/Long_lived_charge_carriers_in_Mn_doped_CdS_quantum_dots_for_photoelectrochemical_cytosensing_ L2 - https://doi.org/10.1002/chem.201405798 DB - PRIME DP - Unbound Medicine ER -