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[Current Topics on Vitamin D. Vitamin D and chronic kidney disease].
Clin Calcium. 2015 Mar; 25(3):413-23.CC

Abstract

CKD-MBD is a new clinical concept which defines a systemic disorder of mineral and bone metabolism as a result of CKD. Although various mineral metabolic factors are involved in its pathogenesis, alteration in vitamin D metabolism plays a crucial role among them. Vitamin D receptor activators (VDRAs), which are traditionally considered a cardinal treatment of secondary hyperparathyroidism, have attracted lots of attention for their potential pleiotropic effects through the activation of the vitamin D receptor expressed in multiple organs. In recent years, the deficiency of vitamin D in CKD patients also has received growing interest. The serum 25 (OH) D levels are considered as a useful prognostic marker, and the significances of nutritional vitamin D supplementation are reviewed from a new perspective.

Authors+Show Affiliations

Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine, Japan.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

jpn

PubMed ID

25716815

Citation

Nakagawa, Yousuke, et al. "[Current Topics On Vitamin D. Vitamin D and Chronic Kidney Disease]." Clinical Calcium, vol. 25, no. 3, 2015, pp. 413-23.
Nakagawa Y, Koizumi M, Fukagawa M. [Current Topics on Vitamin D. Vitamin D and chronic kidney disease]. Clin Calcium. 2015;25(3):413-23.
Nakagawa, Y., Koizumi, M., & Fukagawa, M. (2015). [Current Topics on Vitamin D. Vitamin D and chronic kidney disease]. Clinical Calcium, 25(3), 413-23. https://doi.org/CliCa1503413423
Nakagawa Y, Koizumi M, Fukagawa M. [Current Topics On Vitamin D. Vitamin D and Chronic Kidney Disease]. Clin Calcium. 2015;25(3):413-23. PubMed PMID: 25716815.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Current Topics on Vitamin D. Vitamin D and chronic kidney disease]. AU - Nakagawa,Yousuke, AU - Koizumi,Masahiro, AU - Fukagawa,Masafumi, PY - 2015/2/27/entrez PY - 2015/2/27/pubmed PY - 2015/10/1/medline SP - 413 EP - 23 JF - Clinical calcium JO - Clin Calcium VL - 25 IS - 3 N2 - CKD-MBD is a new clinical concept which defines a systemic disorder of mineral and bone metabolism as a result of CKD. Although various mineral metabolic factors are involved in its pathogenesis, alteration in vitamin D metabolism plays a crucial role among them. Vitamin D receptor activators (VDRAs), which are traditionally considered a cardinal treatment of secondary hyperparathyroidism, have attracted lots of attention for their potential pleiotropic effects through the activation of the vitamin D receptor expressed in multiple organs. In recent years, the deficiency of vitamin D in CKD patients also has received growing interest. The serum 25 (OH) D levels are considered as a useful prognostic marker, and the significances of nutritional vitamin D supplementation are reviewed from a new perspective. SN - 0917-5857 UR - https://www.unboundmedicine.com/medline/citation/25716815/[Current_Topics_on_Vitamin_D__Vitamin_D_and_chronic_kidney_disease]_ L2 - http://www.diseaseinfosearch.org/result/3996 DB - PRIME DP - Unbound Medicine ER -