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Comparative study of DL-selenomethionine vs sodium selenite and seleno-yeast on antioxidant activity and selenium status in laying hens.
Poult Sci. 2015 May; 94(5):965-75.PS

Abstract

The aim of this study was to compare the effect of DL-selenomethionine (SM) with 2 routinely used Se sources, sodium selenite (SS) and seleno-yeast (SY), on relative bioavailability based on antioxidant activity and tissue Se content. Six hundred thirty 131-day-old brown laying hens were randomly assigned to 7 treatments for 168 d (24 wks) with 6 replicates of 15 hens per replicate. The SS and SY animals were supplemented a cornmeal and soybean diet that supplied a total Se 0.3 mg/kg whereas SM was added at 4 different levels to the total Se at 0.1, 0.3, 0.5 and 0.7 mg/kg. All hens fed the Se-supplemented diet showed higher glutathione peroxidase (GSH-Px) activity (P < 0.01), higher superoxide dismutase (SOD) activity (P < 0.05), lower malondialdehyde (MDA) content (P < 0.05) in plasma, and greater Se contents in egg yolks, albumen, leg muscle, breast muscle, liver, and plasma compared with those fed the control diet (P < 0.01). The organic sources (SY and SM) exhibited a greater ability to increase the GSH-Px activity (P < 0.01) and Se content in albumen (P < 0.01), leg, and breast muscles (P = 0.0099 and P = 0.0014, respectively) than the SS that was added at 0.3 mg Se/kg. The higher SM added levels increased the GSH-Px activity until the dose of 0.5mg Se/kg (P < 0.01).The greater Se concentrations in albumen, muscle and liver appeared in the higher SM-added level, as well as above the dose of 0.1 mg Se/kg (P < 0.01). In addition, hens fed the diet with SM accumulated more Se in albumen, leg, and breast muscle than those fed diets with SY (P < 0.05). These results confirmed the higher ability of organic Se sources to increase the antioxidant activity and Se deposition in egg albumen, leg, and breast muscles compared with SS, and demonstrated a significantly better efficiency of SM compared with SY for albumen and muscle Se enrichment.

Authors+Show Affiliations

Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China tjm606@263.net.

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25717085

Citation

Jing, C L., et al. "Comparative Study of DL-selenomethionine Vs Sodium Selenite and Seleno-yeast On Antioxidant Activity and Selenium Status in Laying Hens." Poultry Science, vol. 94, no. 5, 2015, pp. 965-75.
Jing CL, Dong XF, Wang ZM, et al. Comparative study of DL-selenomethionine vs sodium selenite and seleno-yeast on antioxidant activity and selenium status in laying hens. Poult Sci. 2015;94(5):965-75.
Jing, C. L., Dong, X. F., Wang, Z. M., Liu, S., & Tong, J. M. (2015). Comparative study of DL-selenomethionine vs sodium selenite and seleno-yeast on antioxidant activity and selenium status in laying hens. Poultry Science, 94(5), 965-75. https://doi.org/10.3382/ps/pev045
Jing CL, et al. Comparative Study of DL-selenomethionine Vs Sodium Selenite and Seleno-yeast On Antioxidant Activity and Selenium Status in Laying Hens. Poult Sci. 2015;94(5):965-75. PubMed PMID: 25717085.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative study of DL-selenomethionine vs sodium selenite and seleno-yeast on antioxidant activity and selenium status in laying hens. AU - Jing,C L, AU - Dong,X F, AU - Wang,Z M, AU - Liu,S, AU - Tong,J M, Y1 - 2015/02/25/ PY - 2014/12/10/accepted PY - 2015/2/27/entrez PY - 2015/2/27/pubmed PY - 2015/8/8/medline KW - antioxidant KW - laying hen KW - selenium KW - selenium deposition SP - 965 EP - 75 JF - Poultry science JO - Poult. Sci. VL - 94 IS - 5 N2 - The aim of this study was to compare the effect of DL-selenomethionine (SM) with 2 routinely used Se sources, sodium selenite (SS) and seleno-yeast (SY), on relative bioavailability based on antioxidant activity and tissue Se content. Six hundred thirty 131-day-old brown laying hens were randomly assigned to 7 treatments for 168 d (24 wks) with 6 replicates of 15 hens per replicate. The SS and SY animals were supplemented a cornmeal and soybean diet that supplied a total Se 0.3 mg/kg whereas SM was added at 4 different levels to the total Se at 0.1, 0.3, 0.5 and 0.7 mg/kg. All hens fed the Se-supplemented diet showed higher glutathione peroxidase (GSH-Px) activity (P < 0.01), higher superoxide dismutase (SOD) activity (P < 0.05), lower malondialdehyde (MDA) content (P < 0.05) in plasma, and greater Se contents in egg yolks, albumen, leg muscle, breast muscle, liver, and plasma compared with those fed the control diet (P < 0.01). The organic sources (SY and SM) exhibited a greater ability to increase the GSH-Px activity (P < 0.01) and Se content in albumen (P < 0.01), leg, and breast muscles (P = 0.0099 and P = 0.0014, respectively) than the SS that was added at 0.3 mg Se/kg. The higher SM added levels increased the GSH-Px activity until the dose of 0.5mg Se/kg (P < 0.01).The greater Se concentrations in albumen, muscle and liver appeared in the higher SM-added level, as well as above the dose of 0.1 mg Se/kg (P < 0.01). In addition, hens fed the diet with SM accumulated more Se in albumen, leg, and breast muscle than those fed diets with SY (P < 0.05). These results confirmed the higher ability of organic Se sources to increase the antioxidant activity and Se deposition in egg albumen, leg, and breast muscles compared with SS, and demonstrated a significantly better efficiency of SM compared with SY for albumen and muscle Se enrichment. SN - 0032-5791 UR - https://www.unboundmedicine.com/medline/citation/25717085/Comparative_study_of_DL_selenomethionine_vs_sodium_selenite_and_seleno_yeast_on_antioxidant_activity_and_selenium_status_in_laying_hens_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0032-5791(19)32489-7 DB - PRIME DP - Unbound Medicine ER -