Tags

Type your tag names separated by a space and hit enter

Legionnaires' disease in France.
Med Mal Infect. 2015 Mar; 45(3):65-71.MM

Abstract

The aim of this review was to describe the current knowledge of Legionnaires' disease (LD) illustrated by the epidemiological situation in France in 2013. LD is a severe pneumonia commonly caused by Legionella pneumophila serogroup 1. The diagnosis is usually based on the urinary antigen test. This rapid method reduces the delay between clinical suspicion and initiation of an appropriate treatment. However, the availability of a clinical strain is important to improve knowledge of circulating bacteria, to document case clusters, and to identify the sources of contamination. The source of contamination is unknown in most cases. The main contamination sources generating aerosols are water network systems and cooling towers. Thanks to the strengthening of clinical and environmental monitoring and to several guidelines, no epidemic has been reported in France since 2006. Despite these efforts, the number of LD cases has not decreased in recent years. It is essential that applied research continue to better understand the spatial and temporal dynamics of the disease and its characteristics (impact of environmental factors, sources of exposure, strains, host, etc.). Fundamental knowledge has been greatly improved (pathogenesis, immune mechanisms, etc.). The results of this research should help define new strategies for the diagnosis, prevention, and control to decrease the number of LD cases diagnosed every year.

Authors+Show Affiliations

Institut de veille sanitaire, 12, rue du Val-d'Osne, 94415 Saint-Maurice cedex, France. Electronic address: c.campese@invs.sante.fr.Centre national de référence des légionelles, centre de Biologie Est, 59, boulevard Pinel, 69677 Bron, France.Institut de veille sanitaire, 12, rue du Val-d'Osne, 94415 Saint-Maurice cedex, France.Centre national de référence des légionelles, centre de Biologie Est, 59, boulevard Pinel, 69677 Bron, France.Institut de veille sanitaire, 12, rue du Val-d'Osne, 94415 Saint-Maurice cedex, France.Institut de veille sanitaire, 12, rue du Val-d'Osne, 94415 Saint-Maurice cedex, France.Centre national de référence des légionelles, centre de Biologie Est, 59, boulevard Pinel, 69677 Bron, France.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

25722040

Citation

Campèse, C, et al. "Legionnaires' Disease in France." Medecine Et Maladies Infectieuses, vol. 45, no. 3, 2015, pp. 65-71.
Campèse C, Descours G, Lepoutre A, et al. Legionnaires' disease in France. Med Mal Infect. 2015;45(3):65-71.
Campèse, C., Descours, G., Lepoutre, A., Beraud, L., Maine, C., Che, D., & Jarraud, S. (2015). Legionnaires' disease in France. Medecine Et Maladies Infectieuses, 45(3), 65-71. https://doi.org/10.1016/j.medmal.2015.01.015
Campèse C, et al. Legionnaires' Disease in France. Med Mal Infect. 2015;45(3):65-71. PubMed PMID: 25722040.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Legionnaires' disease in France. AU - Campèse,C, AU - Descours,G, AU - Lepoutre,A, AU - Beraud,L, AU - Maine,C, AU - Che,D, AU - Jarraud,S, Y1 - 2015/02/24/ PY - 2014/12/15/received PY - 2014/12/31/revised PY - 2015/01/29/accepted PY - 2015/2/28/entrez PY - 2015/2/28/pubmed PY - 2015/12/22/medline KW - Epidemiology KW - France KW - Legionnaires’ disease KW - Légionellose KW - Épidémiologie SP - 65 EP - 71 JF - Medecine et maladies infectieuses JO - Med Mal Infect VL - 45 IS - 3 N2 - The aim of this review was to describe the current knowledge of Legionnaires' disease (LD) illustrated by the epidemiological situation in France in 2013. LD is a severe pneumonia commonly caused by Legionella pneumophila serogroup 1. The diagnosis is usually based on the urinary antigen test. This rapid method reduces the delay between clinical suspicion and initiation of an appropriate treatment. However, the availability of a clinical strain is important to improve knowledge of circulating bacteria, to document case clusters, and to identify the sources of contamination. The source of contamination is unknown in most cases. The main contamination sources generating aerosols are water network systems and cooling towers. Thanks to the strengthening of clinical and environmental monitoring and to several guidelines, no epidemic has been reported in France since 2006. Despite these efforts, the number of LD cases has not decreased in recent years. It is essential that applied research continue to better understand the spatial and temporal dynamics of the disease and its characteristics (impact of environmental factors, sources of exposure, strains, host, etc.). Fundamental knowledge has been greatly improved (pathogenesis, immune mechanisms, etc.). The results of this research should help define new strategies for the diagnosis, prevention, and control to decrease the number of LD cases diagnosed every year. SN - 1769-6690 UR - https://www.unboundmedicine.com/medline/citation/25722040/Legionnaires'_disease_in_France_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0399-077X(15)00022-0 DB - PRIME DP - Unbound Medicine ER -