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Nut consumption and risk of stroke.
Eur J Epidemiol 2015; 30(3):189-96EJ

Abstract

Nut consumption has been inconsistently associated with risk of stroke. Our aim was to carry out a meta-analysis of prospective studies to assess the relation between nut consumption and stroke risk and mortality. Pertinent studies were identified by a search of PubMed and Embase through June 2014 and by reviewing the references of retrieved articles. Prospective cohort studies that reported relative risks (RRs) with 95% confidence intervals (CIs) for the association between nut consumption and risk of stroke were included. Six articles including nine independent prospective cohorts with 476,181 participants were included in the meta-analysis. The pooled RR of stroke was 0.90 (95% CI 0.83-0.98) comparing the highest with the lowest nut consumption. Stratifying by gender, significant inverse association was observed for females (RR 0.88; 95% CI 0.78-0.98). Sensitivity analysis restricted to studies with adjustment for common confounding factors showed similar results, strengthening the association between nut consumption and stroke risk. Moreover, we observed a trend toward an inverse association between higher nut consumption and stroke mortality (RR 0.86; 95% CI 0.69-1.06), although it is not significant. Current evidence indicated that nut consumption is inversely associated with risk of stroke.

Authors+Show Affiliations

Department of Neurology, Jinling Hospital, Medical School of Nanjing University, 305# East Zhongshan Road, Nanjing, 210002, Jiangsu Province, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis

Language

eng

PubMed ID

25724474

Citation

Zhang, Zhizhong, et al. "Nut Consumption and Risk of Stroke." European Journal of Epidemiology, vol. 30, no. 3, 2015, pp. 189-96.
Zhang Z, Xu G, Wei Y, et al. Nut consumption and risk of stroke. Eur J Epidemiol. 2015;30(3):189-96.
Zhang, Z., Xu, G., Wei, Y., Zhu, W., & Liu, X. (2015). Nut consumption and risk of stroke. European Journal of Epidemiology, 30(3), pp. 189-96. doi:10.1007/s10654-015-9999-3.
Zhang Z, et al. Nut Consumption and Risk of Stroke. Eur J Epidemiol. 2015;30(3):189-96. PubMed PMID: 25724474.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nut consumption and risk of stroke. AU - Zhang,Zhizhong, AU - Xu,Gelin, AU - Wei,Yongyue, AU - Zhu,Wusheng, AU - Liu,Xinfeng, Y1 - 2015/02/28/ PY - 2014/09/01/received PY - 2015/02/12/accepted PY - 2015/3/1/entrez PY - 2015/3/1/pubmed PY - 2015/6/16/medline SP - 189 EP - 96 JF - European journal of epidemiology JO - Eur. J. Epidemiol. VL - 30 IS - 3 N2 - Nut consumption has been inconsistently associated with risk of stroke. Our aim was to carry out a meta-analysis of prospective studies to assess the relation between nut consumption and stroke risk and mortality. Pertinent studies were identified by a search of PubMed and Embase through June 2014 and by reviewing the references of retrieved articles. Prospective cohort studies that reported relative risks (RRs) with 95% confidence intervals (CIs) for the association between nut consumption and risk of stroke were included. Six articles including nine independent prospective cohorts with 476,181 participants were included in the meta-analysis. The pooled RR of stroke was 0.90 (95% CI 0.83-0.98) comparing the highest with the lowest nut consumption. Stratifying by gender, significant inverse association was observed for females (RR 0.88; 95% CI 0.78-0.98). Sensitivity analysis restricted to studies with adjustment for common confounding factors showed similar results, strengthening the association between nut consumption and stroke risk. Moreover, we observed a trend toward an inverse association between higher nut consumption and stroke mortality (RR 0.86; 95% CI 0.69-1.06), although it is not significant. Current evidence indicated that nut consumption is inversely associated with risk of stroke. SN - 1573-7284 UR - https://www.unboundmedicine.com/medline/citation/25724474/Nut_consumption_and_risk_of_stroke_ L2 - https://doi.org/10.1007/s10654-015-9999-3 DB - PRIME DP - Unbound Medicine ER -