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Relationship between sarcopenic obesity and cardiovascular disease risk as estimated by the Framingham risk score.
J Korean Med Sci. 2015 Mar; 30(3):264-71.JK

Abstract

This study was conducted to assess the association between sarcopenic obesity and cardiovascular disease (CVD) risk in Korean adults (n=3,320; ≥40 yr) who participated in the 5th Korean National Health and Nutrition Examination Survey in 2010. The appendicular skeletal muscle mass divided by body weight was calculated for each participant; participants with values <1 standard deviation below the mean reference value (i.e., aged 20-39 yr) were considered sarcopenic. Subjects were further classified into 4 groups according to their obesity (i.e., body mass index ≥25 kg/m(2)) and sarcopenic status. Individuals' 10-yr CVD risk was determined using the Framingham risk model. The sarcopenic obese group had more participants (43.8% men, 14.6% women) with a high risk of CVD (≥20%). The sarcopenic obese group was associated with an increased 10-yr CVD risk than the non-sarcopenic, non-obese group (odds ratio [OR], 2.49; 95% confidence interval [CI], 1.53-4.06, P<0.001 in men; OR, 1.87; 95% CI, 1.02-3.41, P=0.041 in women). Sarcopenic non-obese and non-sarcopenic obese subjects were not associated with an increased 10-yr CVD risk. Sarcopenic obesity, but not non-sarcopenic obesity, was closely associated with an increased CVD risk in Korean adults.

Authors+Show Affiliations

Department of Family Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.Department of Family Medicine, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.Department of Family Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25729248

Citation

Kim, Jeong-Hyeon, et al. "Relationship Between Sarcopenic Obesity and Cardiovascular Disease Risk as Estimated By the Framingham Risk Score." Journal of Korean Medical Science, vol. 30, no. 3, 2015, pp. 264-71.
Kim JH, Cho JJ, Park YS. Relationship between sarcopenic obesity and cardiovascular disease risk as estimated by the Framingham risk score. J Korean Med Sci. 2015;30(3):264-71.
Kim, J. H., Cho, J. J., & Park, Y. S. (2015). Relationship between sarcopenic obesity and cardiovascular disease risk as estimated by the Framingham risk score. Journal of Korean Medical Science, 30(3), 264-71. https://doi.org/10.3346/jkms.2015.30.3.264
Kim JH, Cho JJ, Park YS. Relationship Between Sarcopenic Obesity and Cardiovascular Disease Risk as Estimated By the Framingham Risk Score. J Korean Med Sci. 2015;30(3):264-71. PubMed PMID: 25729248.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship between sarcopenic obesity and cardiovascular disease risk as estimated by the Framingham risk score. AU - Kim,Jeong-Hyeon, AU - Cho,Jung Jin, AU - Park,Yong Soon, Y1 - 2015/02/16/ PY - 2014/06/16/received PY - 2014/11/17/accepted PY - 2015/3/3/entrez PY - 2015/3/3/pubmed PY - 2015/12/19/medline KW - Cardiovascular Diseases KW - KNHANES KW - Obesity KW - Risk Assessment KW - Sarcopenia SP - 264 EP - 71 JF - Journal of Korean medical science JO - J. Korean Med. Sci. VL - 30 IS - 3 N2 - This study was conducted to assess the association between sarcopenic obesity and cardiovascular disease (CVD) risk in Korean adults (n=3,320; ≥40 yr) who participated in the 5th Korean National Health and Nutrition Examination Survey in 2010. The appendicular skeletal muscle mass divided by body weight was calculated for each participant; participants with values <1 standard deviation below the mean reference value (i.e., aged 20-39 yr) were considered sarcopenic. Subjects were further classified into 4 groups according to their obesity (i.e., body mass index ≥25 kg/m(2)) and sarcopenic status. Individuals' 10-yr CVD risk was determined using the Framingham risk model. The sarcopenic obese group had more participants (43.8% men, 14.6% women) with a high risk of CVD (≥20%). The sarcopenic obese group was associated with an increased 10-yr CVD risk than the non-sarcopenic, non-obese group (odds ratio [OR], 2.49; 95% confidence interval [CI], 1.53-4.06, P<0.001 in men; OR, 1.87; 95% CI, 1.02-3.41, P=0.041 in women). Sarcopenic non-obese and non-sarcopenic obese subjects were not associated with an increased 10-yr CVD risk. Sarcopenic obesity, but not non-sarcopenic obesity, was closely associated with an increased CVD risk in Korean adults. SN - 1598-6357 UR - https://www.unboundmedicine.com/medline/citation/25729248/Relationship_between_sarcopenic_obesity_and_cardiovascular_disease_risk_as_estimated_by_the_Framingham_risk_score_ L2 - https://jkms.org/DOIx.php?id=10.3346/jkms.2015.30.3.264 DB - PRIME DP - Unbound Medicine ER -