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Postpubertal cryptorchism. Morphofunctional study with special reference to Leydig's cells.
Eur Urol 1989; 16(6):433-9EU

Abstract

In a group of 17 patients of postpubertal age with unilateral (n = 15) or bilateral (n = 2) cryptorchism, a significant decrease in the tubular diameter was observed, in addition to Leydig cell hyperplasia (many with cytoplasm vacuolization and/or atrophy) in both the cryptorchid testes and in the contralateral scrotal testes. The number of testosterone-positive Leydig cells in testicular tissue sections, studied with peroxidase-antiperoxidase, was diminished in the cryptorchid testes, whereas in the contralateral scrotal testes it was similar to the control group. Together with normal testosterone levels and elevated luteinizing hormone and follicle-stimulating hormone levels in peripheral blood, this leads us to think of a compensated dysfunction of the Leydig cells. This possible lower testosterone production by the Leydig cells in the cryptorchid testis is not borne out morphologically, where the volume of the organelles is similar to the contralateral scrotal testes.

Authors+Show Affiliations

Pathology Department, Tortosa Hospital, Verge de la Cinta, Tarragona, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2574110

Citation

Sirvent, J J., et al. "Postpubertal Cryptorchism. Morphofunctional Study With Special Reference to Leydig's Cells." European Urology, vol. 16, no. 6, 1989, pp. 433-9.
Sirvent JJ, Bernat R, Rodriguez Tolra J, et al. Postpubertal cryptorchism. Morphofunctional study with special reference to Leydig's cells. Eur Urol. 1989;16(6):433-9.
Sirvent, J. J., Bernat, R., Rodriguez Tolra, J., Navarro, M. A., Garcia, B., & Brunet, J. (1989). Postpubertal cryptorchism. Morphofunctional study with special reference to Leydig's cells. European Urology, 16(6), pp. 433-9.
Sirvent JJ, et al. Postpubertal Cryptorchism. Morphofunctional Study With Special Reference to Leydig's Cells. Eur Urol. 1989;16(6):433-9. PubMed PMID: 2574110.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Postpubertal cryptorchism. Morphofunctional study with special reference to Leydig's cells. AU - Sirvent,J J, AU - Bernat,R, AU - Rodriguez Tolra,J, AU - Navarro,M A, AU - Garcia,B, AU - Brunet,J, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez SP - 433 EP - 9 JF - European urology JO - Eur. Urol. VL - 16 IS - 6 N2 - In a group of 17 patients of postpubertal age with unilateral (n = 15) or bilateral (n = 2) cryptorchism, a significant decrease in the tubular diameter was observed, in addition to Leydig cell hyperplasia (many with cytoplasm vacuolization and/or atrophy) in both the cryptorchid testes and in the contralateral scrotal testes. The number of testosterone-positive Leydig cells in testicular tissue sections, studied with peroxidase-antiperoxidase, was diminished in the cryptorchid testes, whereas in the contralateral scrotal testes it was similar to the control group. Together with normal testosterone levels and elevated luteinizing hormone and follicle-stimulating hormone levels in peripheral blood, this leads us to think of a compensated dysfunction of the Leydig cells. This possible lower testosterone production by the Leydig cells in the cryptorchid testis is not borne out morphologically, where the volume of the organelles is similar to the contralateral scrotal testes. SN - 0302-2838 UR - https://www.unboundmedicine.com/medline/citation/2574110/Postpubertal_cryptorchism__Morphofunctional_study_with_special_reference_to_Leydig's_cells_ DB - PRIME DP - Unbound Medicine ER -