Tags

Type your tag names separated by a space and hit enter

Rickets and vitamin D deficiency in Alaska native children.
J Pediatr Endocrinol Metab. 2015 Jul; 28(7-8):815-23.JP

Abstract

BACKGROUND

Rickets and vitamin D deficiency appeared to increase in Alaskan children starting in the 1990s. We evaluated the epidemiology of rickets and vitamin D deficiency in Alaska native (AN) children in 2001-2010.

METHODS

We analyzed 2001-2010 visits with rickets or vitamin D deficiency diagnosis for AN and American Indian children and the general US population aged <10 years. We conducted a case-control study of AN rickets/vitamin D deficient cases and age- and region-matched controls.

RESULTS

In AN children, annual rickets-associated hospitalization rate (2.23/100,000 children/year) was higher than the general US rate (1.23; 95% CI 1.08-1.39). Rickets incidence increased with latitude. Rickets/vitamin D deficiency cases were more likely to have malnutrition (OR 38.1; 95% CI 4.9-294), had similar breast-feeding prevalence, and were less likely to have received vitamin D supplementation (OR 0.23; 95% CI 0.1-0.87) than controls.

CONCLUSIONS

Our findings highlight the importance of latitude, malnutrition, and lack of vitamin D supplementation as risk factors for rickets.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

25741788

Citation

Singleton, Rosalyn, et al. "Rickets and Vitamin D Deficiency in Alaska Native Children." Journal of Pediatric Endocrinology & Metabolism : JPEM, vol. 28, no. 7-8, 2015, pp. 815-23.
Singleton R, Lescher R, Gessner BD, et al. Rickets and vitamin D deficiency in Alaska native children. J Pediatr Endocrinol Metab. 2015;28(7-8):815-23.
Singleton, R., Lescher, R., Gessner, B. D., Benson, M., Bulkow, L., Rosenfeld, J., Thomas, T., Holman, R. C., Haberling, D., Bruce, M., Bartholomew, M., & Tiesinga, J. (2015). Rickets and vitamin D deficiency in Alaska native children. Journal of Pediatric Endocrinology & Metabolism : JPEM, 28(7-8), 815-23. https://doi.org/10.1515/jpem-2014-0446
Singleton R, et al. Rickets and Vitamin D Deficiency in Alaska Native Children. J Pediatr Endocrinol Metab. 2015;28(7-8):815-23. PubMed PMID: 25741788.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rickets and vitamin D deficiency in Alaska native children. AU - Singleton,Rosalyn, AU - Lescher,Rachel, AU - Gessner,Bradford D, AU - Benson,Matthew, AU - Bulkow,Lisa, AU - Rosenfeld,John, AU - Thomas,Timothy, AU - Holman,Robert C, AU - Haberling,Dana, AU - Bruce,Michael, AU - Bartholomew,Michael, AU - Tiesinga,James, PY - 2014/10/28/received PY - 2015/01/29/accepted PY - 2015/3/6/entrez PY - 2015/3/6/pubmed PY - 2016/4/15/medline SP - 815 EP - 23 JF - Journal of pediatric endocrinology & metabolism : JPEM JO - J. Pediatr. Endocrinol. Metab. VL - 28 IS - 7-8 N2 - BACKGROUND: Rickets and vitamin D deficiency appeared to increase in Alaskan children starting in the 1990s. We evaluated the epidemiology of rickets and vitamin D deficiency in Alaska native (AN) children in 2001-2010. METHODS: We analyzed 2001-2010 visits with rickets or vitamin D deficiency diagnosis for AN and American Indian children and the general US population aged <10 years. We conducted a case-control study of AN rickets/vitamin D deficient cases and age- and region-matched controls. RESULTS: In AN children, annual rickets-associated hospitalization rate (2.23/100,000 children/year) was higher than the general US rate (1.23; 95% CI 1.08-1.39). Rickets incidence increased with latitude. Rickets/vitamin D deficiency cases were more likely to have malnutrition (OR 38.1; 95% CI 4.9-294), had similar breast-feeding prevalence, and were less likely to have received vitamin D supplementation (OR 0.23; 95% CI 0.1-0.87) than controls. CONCLUSIONS: Our findings highlight the importance of latitude, malnutrition, and lack of vitamin D supplementation as risk factors for rickets. SN - 2191-0251 UR - https://www.unboundmedicine.com/medline/citation/25741788/Rickets_and_vitamin_D_deficiency_in_Alaska_native_children_ L2 - https://www.degruyter.com/doi/10.1515/jpem-2014-0446 DB - PRIME DP - Unbound Medicine ER -