TY - JOUR T1 - Results of oral contraceptive epidemiologic studies regarding neoplastic and cardiovascular effects. A1 - Grimes,D A, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez KW - Biology KW - Breast Cancer KW - Cancer KW - Cardiovascular Effects KW - Cervical Cancer KW - Contraception KW - Contraceptive Methods--beneficial effects KW - Contraceptive Methods--side effects KW - Critique KW - Demographic Factors KW - Diseases KW - Embolism KW - Endometrial Cancer KW - Epidemiologic Methods KW - Family Planning KW - Ischemia KW - Mortality--women KW - Neoplasms KW - Oral Contraceptives--beneficial effects KW - Oral Contraceptives--side effects KW - Ovarian Cancer KW - Physiology KW - Population KW - Population Dynamics KW - Research Methodology KW - Thromboembolism KW - Vascular Diseases SP - 27 EP - 33 JF - International journal of fertility JO - Int J Fertil VL - 34 Suppl N2 - Over the past three decades, much of the research on oral contraceptives has focused on cardiovascular and neoplastic effects. Results of recent United States studies have shown no increased risk of death among users of oral contraceptives, although an increased risk of idiopathic venous thromboembolism has been a consistent finding. There is compelling evidence that oral contraceptive use provides significant protection against endometrial and ovarian cancer, and that this protection lasts at least 15 years. In addition, no clear association has been found between oral contraceptive use and breast cancer or cervical cancer. Data on hepatocellular carcinoma and malignant melanoma are inconclusive. SN - 0020-725X UR - https://www.unboundmedicine.com/medline/citation/2576254/Results_of_oral_contraceptive_epidemiologic_studies_regarding_neoplastic_and_cardiovascular_effects_ DB - PRIME DP - Unbound Medicine ER -