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[Somatostatin in the emergency treatment of upper digestive hemorrhage in patients with portal hypertension].
Acta Gastroenterol Latinoam. 1989; 19(3):139-46.AG

Abstract

During a 2-yr period 15 patients (17 episodes) with variceal bleeding (VB) and 7 with cirrhosis and acute gastroduodenal haemorrhage (GDH) received intravenous somatostatin (250 mcg per hr after a bolus of 250 mcg). Initial control of bleeding was achieved in 13 (76%) with VB and in all with GDH. Three of the 4 patients with VB and 2 with GDH who rebled during treatment were controlled increasing the infusion to 500 mcg/hr. Patients with VB received somatostatin for 24 hrs, time selected for initiating injection sclerotherapy, and those with GDH for 48-72 hrs. At 24 hrs 71% of patients with VB and all with GDH were free of bleeding. Combining different therapies VB was controlled in 16 of the 17 episodes (94%) with only one death. No complications were observed in any of the 22 patients treated.

Authors+Show Affiliations

Hospital Italiano de Buenos Aires, Terapia Intensiva y Gastroenterología.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

2576849

Citation

Villamil, F G., et al. "[Somatostatin in the Emergency Treatment of Upper Digestive Hemorrhage in Patients With Portal Hypertension]." Acta Gastroenterologica Latinoamericana, vol. 19, no. 3, 1989, pp. 139-46.
Villamil FG, Perman M, Gallesio A, et al. [Somatostatin in the emergency treatment of upper digestive hemorrhage in patients with portal hypertension]. Acta Gastroenterol Latinoam. 1989;19(3):139-46.
Villamil, F. G., Perman, M., Gallesio, A., Butera, M., Soifer, L., Aziz, H., & San Román, E. (1989). [Somatostatin in the emergency treatment of upper digestive hemorrhage in patients with portal hypertension]. Acta Gastroenterologica Latinoamericana, 19(3), 139-46.
Villamil FG, et al. [Somatostatin in the Emergency Treatment of Upper Digestive Hemorrhage in Patients With Portal Hypertension]. Acta Gastroenterol Latinoam. 1989;19(3):139-46. PubMed PMID: 2576849.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Somatostatin in the emergency treatment of upper digestive hemorrhage in patients with portal hypertension]. AU - Villamil,F G, AU - Perman,M, AU - Gallesio,A, AU - Butera,M, AU - Soifer,L, AU - Aziz,H, AU - San Román,E, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez SP - 139 EP - 46 JF - Acta gastroenterologica Latinoamericana JO - Acta Gastroenterol Latinoam VL - 19 IS - 3 N2 - During a 2-yr period 15 patients (17 episodes) with variceal bleeding (VB) and 7 with cirrhosis and acute gastroduodenal haemorrhage (GDH) received intravenous somatostatin (250 mcg per hr after a bolus of 250 mcg). Initial control of bleeding was achieved in 13 (76%) with VB and in all with GDH. Three of the 4 patients with VB and 2 with GDH who rebled during treatment were controlled increasing the infusion to 500 mcg/hr. Patients with VB received somatostatin for 24 hrs, time selected for initiating injection sclerotherapy, and those with GDH for 48-72 hrs. At 24 hrs 71% of patients with VB and all with GDH were free of bleeding. Combining different therapies VB was controlled in 16 of the 17 episodes (94%) with only one death. No complications were observed in any of the 22 patients treated. SN - 0300-9033 UR - https://www.unboundmedicine.com/medline/citation/2576849/[Somatostatin_in_the_emergency_treatment_of_upper_digestive_hemorrhage_in_patients_with_portal_hypertension]_ L2 - http://www.diseaseinfosearch.org/result/5881 DB - PRIME DP - Unbound Medicine ER -