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Pernicious anemia presenting as catatonia: correlating vitamin B12 levels and catatonic symptoms.
Gen Hosp Psychiatry. 2015 May-Jun; 37(3):273.e5-7.GH

Abstract

Pernicious anemia has been associated with various psychiatric manifestations, such as depression, mania and psychosis. Psychiatric symptoms can sometimes occur without hematological and neurological abnormalities and can be prodromal of vitamin B12 deficiency. We report a case of autoimmune B12 deficiency presenting as catatonia without signs of anemia or macrocytosis, in which a correlation was found between the patient's B12 blood levels and catatonic symptoms over time. This catatonic episode was successfully treated with only lorazepam and adequate doses of cyanocobalamin.

Authors+Show Affiliations

EPSM des Flandres, Bailleul, France; Department of Psychiatry, CHU Lille, Lille, France. Electronic address: damien.bram@gmail.com.Université Lille Nord de France, Lille, France; Department of Psychiatry, CHU Lille, Lille, France. Electronic address: maxime.bubrovszky@chru-lille.fr.EPSM des Flandres, Bailleul, France. Electronic address: Jean-Paul.Durand@epsm-des-flandres.com.Université Lille Nord de France, Lille, France; Department of Internal Medicine, National Reference Center for Rare Autoimmune and Systemic Diseases, CHRU Lille, Lille, France. Electronic address: guillaume.lefevre@chru-lille.fr.Université Lille Nord de France, Lille, France; Department of Internal Medicine, National Reference Center for Rare Autoimmune and Systemic Diseases, CHRU Lille, Lille, France. Electronic address: sandrine.dubois@chru-lille.fr.Université Lille Nord de France, Lille, France; Department of Psychiatry, CHU Lille, Lille, France. Electronic address: guillaume.vaiva@chru-lille.fr.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

25774050

Citation

Bram, Damien, et al. "Pernicious Anemia Presenting as Catatonia: Correlating Vitamin B12 Levels and Catatonic Symptoms." General Hospital Psychiatry, vol. 37, no. 3, 2015, pp. 273.e5-7.
Bram D, Bubrovszky M, Durand JP, et al. Pernicious anemia presenting as catatonia: correlating vitamin B12 levels and catatonic symptoms. Gen Hosp Psychiatry. 2015;37(3):273.e5-7.
Bram, D., Bubrovszky, M., Durand, J. P., Lefevre, G., Morell-Dubois, S., & Vaiva, G. (2015). Pernicious anemia presenting as catatonia: correlating vitamin B12 levels and catatonic symptoms. General Hospital Psychiatry, 37(3), e5-7. https://doi.org/10.1016/j.genhosppsych.2015.02.003
Bram D, et al. Pernicious Anemia Presenting as Catatonia: Correlating Vitamin B12 Levels and Catatonic Symptoms. Gen Hosp Psychiatry. 2015 May-Jun;37(3):273.e5-7. PubMed PMID: 25774050.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pernicious anemia presenting as catatonia: correlating vitamin B12 levels and catatonic symptoms. AU - Bram,Damien, AU - Bubrovszky,Maxime, AU - Durand,Jean-Paul, AU - Lefevre,Guillaume, AU - Morell-Dubois,Sandrine, AU - Vaiva,Guillaume, Y1 - 2015/02/23/ PY - 2014/08/14/received PY - 2015/02/12/revised PY - 2015/02/17/accepted PY - 2015/3/17/entrez PY - 2015/3/17/pubmed PY - 2016/2/26/medline KW - Catatonia KW - Psychiatry KW - Vitamin B12 deficiency KW - Vitamins SP - 273.e5 EP - 7 JF - General hospital psychiatry JO - Gen Hosp Psychiatry VL - 37 IS - 3 N2 - Pernicious anemia has been associated with various psychiatric manifestations, such as depression, mania and psychosis. Psychiatric symptoms can sometimes occur without hematological and neurological abnormalities and can be prodromal of vitamin B12 deficiency. We report a case of autoimmune B12 deficiency presenting as catatonia without signs of anemia or macrocytosis, in which a correlation was found between the patient's B12 blood levels and catatonic symptoms over time. This catatonic episode was successfully treated with only lorazepam and adequate doses of cyanocobalamin. SN - 1873-7714 UR - https://www.unboundmedicine.com/medline/citation/25774050/Pernicious_anemia_presenting_as_catatonia:_correlating_vitamin_B12_levels_and_catatonic_symptoms_ DB - PRIME DP - Unbound Medicine ER -