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Comparative study on the antioxidant activities of extracts of Coreopsis tinctoria flowering tops from Kunlun Mountains, Xinjiang, north-western China.
Nat Prod Res. 2016; 30(4):429-32.NP

Abstract

Coreopsis tinctoria flowering tops (CTFs) from the Kunlun Mountains in Xinjing (north-western China) have been used for tea production for about a century. This study aims to assess the antioxidant activities and total phenolic, flavonoid and proanthocyanidin contents of various solvent extracts of CTF. CTF was extracted using n-hexane, chloroform, ethyl acetate, n-butanol, 75% aqueous ethanol (AEE) and water. The antioxidant activities of the CTF extracts were investigated through DPPH, ABTS, *OH, *O2(-), total antioxidant capacity and reducing power assays. The results showed that n-butanol extract showed the highest contents of total phenols and flavonoids, with DPPH, ABTS and *OH radical-scavenging activities with IC50 values of 134, 90.72 and 13.8 μg mL(-1), respectively. The AEE demonstrated the strongest DPPH and ABTS radical-scavenging activities, with IC50 values of 103 and 75.16 μg mL(-1), respectively. Given its high antioxidant effect, CTF is a good source of natural antioxidants or functional food materials.

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Authors+Show Affiliations

Yao X
a College of Pharmacy, Shihezi University , Shihezi , 832000 Xinjiang , P.R. China. b Ministry of Education Key Laboratory of Xinjiang Endemic Phytomedicine Resources, Shihezi University , Shihezi , 832000 Xinjiang , P.R. China.
Gu C
c School of Chemistry and Chemical Engineering, Shihezi University , Shihezi , 832002 Xinjiang , P.R. China.
Tian L
a College of Pharmacy, Shihezi University , Shihezi , 832000 Xinjiang , P.R. China. b Ministry of Education Key Laboratory of Xinjiang Endemic Phytomedicine Resources, Shihezi University , Shihezi , 832000 Xinjiang , P.R. China.
Wang X
a College of Pharmacy, Shihezi University , Shihezi , 832000 Xinjiang , P.R. China. b Ministry of Education Key Laboratory of Xinjiang Endemic Phytomedicine Resources, Shihezi University , Shihezi , 832000 Xinjiang , P.R. China.
Tang H
a College of Pharmacy, Shihezi University , Shihezi , 832000 Xinjiang , P.R. China. b Ministry of Education Key Laboratory of Xinjiang Endemic Phytomedicine Resources, Shihezi University , Shihezi , 832000 Xinjiang , P.R. China.

MeSH

AntioxidantsBiphenyl CompoundsChinaCoreopsisFlavonoidsFlowering TopsFree Radical ScavengersHydroxyl RadicalPhenolsPicratesPlant ExtractsProanthocyanidinsSolvents

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

25776853

Citation

Yao, Xincheng, et al. "Comparative Study On the Antioxidant Activities of Extracts of Coreopsis Tinctoria Flowering Tops From Kunlun Mountains, Xinjiang, North-western China." Natural Product Research, vol. 30, no. 4, 2016, pp. 429-32.
Yao X, Gu C, Tian L, et al. Comparative study on the antioxidant activities of extracts of Coreopsis tinctoria flowering tops from Kunlun Mountains, Xinjiang, north-western China. Nat Prod Res. 2016;30(4):429-32.
Yao, X., Gu, C., Tian, L., Wang, X., & Tang, H. (2016). Comparative study on the antioxidant activities of extracts of Coreopsis tinctoria flowering tops from Kunlun Mountains, Xinjiang, north-western China. Natural Product Research, 30(4), 429-32. https://doi.org/10.1080/14786419.2015.1015019
Yao X, et al. Comparative Study On the Antioxidant Activities of Extracts of Coreopsis Tinctoria Flowering Tops From Kunlun Mountains, Xinjiang, North-western China. Nat Prod Res. 2016;30(4):429-32. PubMed PMID: 25776853.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative study on the antioxidant activities of extracts of Coreopsis tinctoria flowering tops from Kunlun Mountains, Xinjiang, north-western China. AU - Yao,Xincheng, AU - Gu,Chengzhi, AU - Tian,Liping, AU - Wang,Xinbing, AU - Tang,Hui, Y1 - 2015/03/17/ PY - 2015/3/18/entrez PY - 2015/3/18/pubmed PY - 2016/9/15/medline KW - Coreopsis tinctoria Nutt KW - antioxidant activity KW - radical scavenging activity SP - 429 EP - 32 JF - Natural product research JO - Nat Prod Res VL - 30 IS - 4 N2 - Coreopsis tinctoria flowering tops (CTFs) from the Kunlun Mountains in Xinjing (north-western China) have been used for tea production for about a century. This study aims to assess the antioxidant activities and total phenolic, flavonoid and proanthocyanidin contents of various solvent extracts of CTF. CTF was extracted using n-hexane, chloroform, ethyl acetate, n-butanol, 75% aqueous ethanol (AEE) and water. The antioxidant activities of the CTF extracts were investigated through DPPH, ABTS, *OH, *O2(-), total antioxidant capacity and reducing power assays. The results showed that n-butanol extract showed the highest contents of total phenols and flavonoids, with DPPH, ABTS and *OH radical-scavenging activities with IC50 values of 134, 90.72 and 13.8 μg mL(-1), respectively. The AEE demonstrated the strongest DPPH and ABTS radical-scavenging activities, with IC50 values of 103 and 75.16 μg mL(-1), respectively. Given its high antioxidant effect, CTF is a good source of natural antioxidants or functional food materials. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/25776853/Comparative_study_on_the_antioxidant_activities_of_extracts_of_Coreopsis_tinctoria_flowering_tops_from_Kunlun_Mountains_Xinjiang_north_western_China_ DB - PRIME DP - Unbound Medicine ER -