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Familial colorectal cancer syndromes: an overview of clinical management.
Expert Rev Gastroenterol Hepatol. 2015 Jun; 9(6):757-64.ER

Abstract

Familial colorectal cancer syndromes pose a complex challenge to the treating clinician. Once a syndrome is recognized, genetic testing is often required to confirm the clinical suspicion. Management from that point is usually based on disease-specific guideline recommendations targeting risk reduction for the patient and their relatives through surgery, surveillance and chemoprophylaxis. The aim of this paper is to provide an up-to-date summary of the most common familial syndromes and their medical and surgical management, with specific emphasis on evidence-based interventions that improve patient outcome, and to present the information in a manner that is easily readable and clinically relevant to the treating clinician.

Authors+Show Affiliations

Colorectal Surgery Unit, Department of Surgery, The Royal Melbourne Hospital, Melbourne, VIC, Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

25779305

Citation

Sammour, Tarik, et al. "Familial Colorectal Cancer Syndromes: an Overview of Clinical Management." Expert Review of Gastroenterology & Hepatology, vol. 9, no. 6, 2015, pp. 757-64.
Sammour T, Hayes IP, Hill AG, et al. Familial colorectal cancer syndromes: an overview of clinical management. Expert Rev Gastroenterol Hepatol. 2015;9(6):757-64.
Sammour, T., Hayes, I. P., Hill, A. G., Macrae, F. A., & Winter, D. C. (2015). Familial colorectal cancer syndromes: an overview of clinical management. Expert Review of Gastroenterology & Hepatology, 9(6), 757-64. https://doi.org/10.1586/17474124.2015.1026328
Sammour T, et al. Familial Colorectal Cancer Syndromes: an Overview of Clinical Management. Expert Rev Gastroenterol Hepatol. 2015;9(6):757-64. PubMed PMID: 25779305.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Familial colorectal cancer syndromes: an overview of clinical management. AU - Sammour,Tarik, AU - Hayes,Ian P, AU - Hill,Andrew G, AU - Macrae,Finlay A, AU - Winter,Des C, Y1 - 2015/03/16/ PY - 2015/3/18/entrez PY - 2015/3/18/pubmed PY - 2016/2/18/medline KW - Lynch KW - adenoma KW - colorectal cancer KW - familial KW - polyposis SP - 757 EP - 64 JF - Expert review of gastroenterology & hepatology JO - Expert Rev Gastroenterol Hepatol VL - 9 IS - 6 N2 - Familial colorectal cancer syndromes pose a complex challenge to the treating clinician. Once a syndrome is recognized, genetic testing is often required to confirm the clinical suspicion. Management from that point is usually based on disease-specific guideline recommendations targeting risk reduction for the patient and their relatives through surgery, surveillance and chemoprophylaxis. The aim of this paper is to provide an up-to-date summary of the most common familial syndromes and their medical and surgical management, with specific emphasis on evidence-based interventions that improve patient outcome, and to present the information in a manner that is easily readable and clinically relevant to the treating clinician. SN - 1747-4132 UR - https://www.unboundmedicine.com/medline/citation/25779305/Familial_colorectal_cancer_syndromes:_an_overview_of_clinical_management_ L2 - http://www.tandfonline.com/doi/full/10.1586/17474124.2015.1026328 DB - PRIME DP - Unbound Medicine ER -