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Clinical characteristics, treatment patterns, and outcomes of primary canaliculitis among patients in Beijing, China.
Biomed Res Int. 2015; 2015:904756.BR

Abstract

BACKGROUND

Canaliculitis may cause punctal or canalicular swelling, discharge, erythema, and sometimes concretions. This study examined the clinical characteristics, treatment patterns, and outcomes of primary canaliculitis from patients at a top-rated hospital in Beijing, China.

METHODS

Medical records of 16 patients (retrospective case series) were studied.

RESULTS

This study included four males and twelve females with a median age of 72.5 years. The mean and the median follow-up time were 10.4 months and 6 months, respectively. The mostly observed clinical symptoms were epiphora with discharge (94%), while the mostly observed signs included pouting punctum (75%) and punctal regurgitation of concretions under syringing (75%). Only the symptoms of one patient among those with conservative therapy completely resolved within two-year follow-up. Curettage therapy was found to partly resolve the clinical symptoms and signs within the follow-up of four weeks. Fifteen patients finally received curettage with punctoplasty, and symptoms completely resolved in fourteen patients after one surgery.

CONCLUSIONS

Syringing with pressing of lacrimal sac area may help better diagnosis of canaliculitis. Additionally, curettage with punctoplasty is recommended for thorough removal of concretions and complete resolution of canaliculitis.

Authors+Show Affiliations

Department of Ophthalmology, People's Eye Institute, Peking University People's Hospital, Beijing 100044, China ; Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing 100044, China ; Peking University Center for Human Disease Genomics, Peking University Health Science Center, Beijing 100191, China.Peking University Medical Informatics Center, Beijing 100191, China.Department of Ophthalmology, People's Eye Institute, Peking University People's Hospital, Beijing 100044, China ; Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing 100044, China.Department of Ophthalmology, People's Eye Institute, Peking University People's Hospital, Beijing 100044, China ; Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing 100044, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25785275

Citation

Zhang, Qin, et al. "Clinical Characteristics, Treatment Patterns, and Outcomes of Primary Canaliculitis Among Patients in Beijing, China." BioMed Research International, vol. 2015, 2015, p. 904756.
Zhang Q, Xu B, Li XX, et al. Clinical characteristics, treatment patterns, and outcomes of primary canaliculitis among patients in Beijing, China. Biomed Res Int. 2015;2015:904756.
Zhang, Q., Xu, B., Li, X. X., & Li, M. W. (2015). Clinical characteristics, treatment patterns, and outcomes of primary canaliculitis among patients in Beijing, China. BioMed Research International, 2015, 904756. https://doi.org/10.1155/2015/904756
Zhang Q, et al. Clinical Characteristics, Treatment Patterns, and Outcomes of Primary Canaliculitis Among Patients in Beijing, China. Biomed Res Int. 2015;2015:904756. PubMed PMID: 25785275.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical characteristics, treatment patterns, and outcomes of primary canaliculitis among patients in Beijing, China. AU - Zhang,Qin, AU - Xu,Beibei, AU - Li,Xiao-Xin, AU - Li,Ming-Wu, Y1 - 2015/02/17/ PY - 2015/01/06/received PY - 2015/01/28/accepted PY - 2015/3/19/entrez PY - 2015/3/19/pubmed PY - 2016/1/8/medline SP - 904756 EP - 904756 JF - BioMed research international JO - Biomed Res Int VL - 2015 N2 - BACKGROUND: Canaliculitis may cause punctal or canalicular swelling, discharge, erythema, and sometimes concretions. This study examined the clinical characteristics, treatment patterns, and outcomes of primary canaliculitis from patients at a top-rated hospital in Beijing, China. METHODS: Medical records of 16 patients (retrospective case series) were studied. RESULTS: This study included four males and twelve females with a median age of 72.5 years. The mean and the median follow-up time were 10.4 months and 6 months, respectively. The mostly observed clinical symptoms were epiphora with discharge (94%), while the mostly observed signs included pouting punctum (75%) and punctal regurgitation of concretions under syringing (75%). Only the symptoms of one patient among those with conservative therapy completely resolved within two-year follow-up. Curettage therapy was found to partly resolve the clinical symptoms and signs within the follow-up of four weeks. Fifteen patients finally received curettage with punctoplasty, and symptoms completely resolved in fourteen patients after one surgery. CONCLUSIONS: Syringing with pressing of lacrimal sac area may help better diagnosis of canaliculitis. Additionally, curettage with punctoplasty is recommended for thorough removal of concretions and complete resolution of canaliculitis. SN - 2314-6141 UR - https://www.unboundmedicine.com/medline/citation/25785275/Clinical_characteristics_treatment_patterns_and_outcomes_of_primary_canaliculitis_among_patients_in_Beijing_China_ L2 - https://dx.doi.org/10.1155/2015/904756 DB - PRIME DP - Unbound Medicine ER -