Tags

Type your tag names separated by a space and hit enter

Higher risk of developing a subsequent migraine in adults with nonapnea sleep disorders: A nationwide population-based cohort study.
Eur J Intern Med. 2015 May; 26(4):232-6.EJ

Abstract

OBJECTIVE

This nationwide population-based cohort study evaluated the effect of nonapnea sleep disorders (NSDs) on the subsequent development of a migraine.

METHODS

We identified 46,777 patients aged 20 years and older who were diagnosed with an NSD (ICD-9-CM: 307.4 or 780.5) and without coding for apnea-sleep disorders (ICD-9-CM: 780.51, 780.53, or 780.57) between 2000 and 2002 as the sleep disorder (SD) cohort. A comparison cohort of 93,552 people was enrolled. We calculated the adjusted hazard ratio (aHR) for developing a migraine (ICD-9-CM: 346) after adjusting for age, sex, comorbidity, and drug use. A Kaplan-Meier analysis was used to measure the cumulative incidence of a migraine between 2 curves until the end of 2011.

RESULTS

The cumulative incidence of a migraine was significantly higher in the SD cohort. The aHR for developing a migraine in the SD cohort was 3.52 (95% CI=3.28-3.79). The risk of developing a migraine with an NSD was higher in men (aHR=4.31) than in women (aHR=3.35). The age-stratified effect of an NSD on developing a migraine was highest among patients aged 55 years and younger. Higher risks of developing a migraine were observed among the participants without any comorbidity and without any drug treatment for their insomnia.

CONCLUSION

The findings of this population-based cohort study indicate a higher risk of developing a subsequent migraine in patients with an NSD, which could be considered an independent, predisposing factor for developing subsequent a migraine in adulthood.

Authors+Show Affiliations

Department of Neurosurgery, Hualien Tzu Chi General Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; College of Medicine, Tzu Chi University, Hualien, Taiwan.Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan; College of Medicine, China Medical University, Taichung, Taiwan.Graduate Institute of Clinical Medical Science and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan; Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan. Electronic address: d10040@mail.cmuh.org.tw.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25801248

Citation

Harnod, Tomor, et al. "Higher Risk of Developing a Subsequent Migraine in Adults With Nonapnea Sleep Disorders: a Nationwide Population-based Cohort Study." European Journal of Internal Medicine, vol. 26, no. 4, 2015, pp. 232-6.
Harnod T, Wang YC, Kao CH. Higher risk of developing a subsequent migraine in adults with nonapnea sleep disorders: A nationwide population-based cohort study. Eur J Intern Med. 2015;26(4):232-6.
Harnod, T., Wang, Y. C., & Kao, C. H. (2015). Higher risk of developing a subsequent migraine in adults with nonapnea sleep disorders: A nationwide population-based cohort study. European Journal of Internal Medicine, 26(4), 232-6. https://doi.org/10.1016/j.ejim.2015.03.002
Harnod T, Wang YC, Kao CH. Higher Risk of Developing a Subsequent Migraine in Adults With Nonapnea Sleep Disorders: a Nationwide Population-based Cohort Study. Eur J Intern Med. 2015;26(4):232-6. PubMed PMID: 25801248.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Higher risk of developing a subsequent migraine in adults with nonapnea sleep disorders: A nationwide population-based cohort study. AU - Harnod,Tomor, AU - Wang,Yu-Chiao, AU - Kao,Chia-Hung, Y1 - 2015/03/19/ PY - 2015/02/05/received PY - 2015/02/25/revised PY - 2015/03/02/accepted PY - 2015/3/25/entrez PY - 2015/3/25/pubmed PY - 2016/1/15/medline KW - Cohort study KW - Insomnia KW - Migraine KW - National Health Insurance (NHI) SP - 232 EP - 6 JF - European journal of internal medicine JO - Eur J Intern Med VL - 26 IS - 4 N2 - OBJECTIVE: This nationwide population-based cohort study evaluated the effect of nonapnea sleep disorders (NSDs) on the subsequent development of a migraine. METHODS: We identified 46,777 patients aged 20 years and older who were diagnosed with an NSD (ICD-9-CM: 307.4 or 780.5) and without coding for apnea-sleep disorders (ICD-9-CM: 780.51, 780.53, or 780.57) between 2000 and 2002 as the sleep disorder (SD) cohort. A comparison cohort of 93,552 people was enrolled. We calculated the adjusted hazard ratio (aHR) for developing a migraine (ICD-9-CM: 346) after adjusting for age, sex, comorbidity, and drug use. A Kaplan-Meier analysis was used to measure the cumulative incidence of a migraine between 2 curves until the end of 2011. RESULTS: The cumulative incidence of a migraine was significantly higher in the SD cohort. The aHR for developing a migraine in the SD cohort was 3.52 (95% CI=3.28-3.79). The risk of developing a migraine with an NSD was higher in men (aHR=4.31) than in women (aHR=3.35). The age-stratified effect of an NSD on developing a migraine was highest among patients aged 55 years and younger. Higher risks of developing a migraine were observed among the participants without any comorbidity and without any drug treatment for their insomnia. CONCLUSION: The findings of this population-based cohort study indicate a higher risk of developing a subsequent migraine in patients with an NSD, which could be considered an independent, predisposing factor for developing subsequent a migraine in adulthood. SN - 1879-0828 UR - https://www.unboundmedicine.com/medline/citation/25801248/Higher_risk_of_developing_a_subsequent_migraine_in_adults_with_nonapnea_sleep_disorders:_A_nationwide_population_based_cohort_study_ DB - PRIME DP - Unbound Medicine ER -