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Aerosol transmission of infectious disease.

Abstract

OBJECTIVE

The concept of aerosol transmission is developed to resolve limitations in conventional definitions of airborne and droplet transmission.

METHODS

The method was literature review.

RESULTS

An infectious aerosol is a collection of pathogen-laden particles in air. Aerosol particles may deposit onto or be inhaled by a susceptible person. Aerosol transmission is biologically plausible when infectious aerosols are generated by or from an infectious person, the pathogen remains viable in the environment for some period of time, and the target tissues in which the pathogen initiates infection are accessible to the aerosol. Biological plausibility of aerosol transmission is evaluated for Severe Acute Respiratory Syndrome coronavirus and norovirus and discussed for Mycobacterium tuberculosis, influenza, and Ebola virus.

CONCLUSIONS

Aerosol transmission reflects a modern understanding of aerosol science and allows physically appropriate explanation and intervention selection for infectious diseases.

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  • Authors+Show Affiliations

    ,

    From the School of Public Health, University of Illinois at Chicago.

    Source

    MeSH

    Aerosols
    Air Microbiology
    Caliciviridae Infections
    Coronavirus
    Cough
    Disease Transmission, Infectious
    Humans
    Norovirus
    Particle Size
    Severe Acute Respiratory Syndrome
    Sneezing

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    25816216