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Hypercalcemic crisis due to primary hyperparathyroidism occurring concomitantly with Graves' disease.

Abstract

We herein describe a case of hypercalcemic crisis in a 52-year-old Japanese woman. She suffered from thirst and fatigue for one month. Her serum calcium (a) levels were 19.0 mg/dL, and she was diagnosed with hypercalcemic crisis. Circulating levels of parathyroid and thyroid hormones were elevated. She was diagnosed with primary hyperparathyroidism accompanied by Graves' disease. Thyroparathyroidectomy was performed after circulating levels of Ca and thyroid hormones were normalized. Both of primary hyperparathyroidism and Graves' disease can contribute and accelerate hypercalcemia, resulting in a state of crisis. The possibility of their coexistence should therefore be taken into consideration in cases of hypercalcemia.

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  • Authors+Show Affiliations

    ,

    Department of Medicine, Diabetes, Metabolism and Endocrinology, Matsuyama Red Cross Hospital, Japan.

    , , , ,

    Source

    MeSH

    Female
    Graves Disease
    Humans
    Hypercalcemia
    Hyperparathyroidism, Primary
    Middle Aged
    Parathyroid Hormone
    Thyroid Hormones

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    25832948

    Citation

    Yokomoto, Maki, et al. "Hypercalcemic Crisis Due to Primary Hyperparathyroidism Occurring Concomitantly With Graves' Disease." Internal Medicine (Tokyo, Japan), vol. 54, no. 7, 2015, pp. 813-8.
    Yokomoto M, Minamoto M, Utsunomiya D, et al. Hypercalcemic crisis due to primary hyperparathyroidism occurring concomitantly with Graves' disease. Intern Med. 2015;54(7):813-8.
    Yokomoto, M., Minamoto, M., Utsunomiya, D., Umakoshi, H., Fukuoka, T., & Kondo, S. (2015). Hypercalcemic crisis due to primary hyperparathyroidism occurring concomitantly with Graves' disease. Internal Medicine (Tokyo, Japan), 54(7), pp. 813-8. doi:10.2169/internalmedicine.54.2605.
    Yokomoto M, et al. Hypercalcemic Crisis Due to Primary Hyperparathyroidism Occurring Concomitantly With Graves' Disease. Intern Med. 2015;54(7):813-8. PubMed PMID: 25832948.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Hypercalcemic crisis due to primary hyperparathyroidism occurring concomitantly with Graves' disease. AU - Yokomoto,Maki, AU - Minamoto,Mayu, AU - Utsunomiya,Daisuke, AU - Umakoshi,Hironobu, AU - Fukuoka,Tomikazu, AU - Kondo,Shiori, Y1 - 2015/04/01/ PY - 2015/4/3/entrez PY - 2015/4/4/pubmed PY - 2015/9/15/medline SP - 813 EP - 8 JF - Internal medicine (Tokyo, Japan) JO - Intern. Med. VL - 54 IS - 7 N2 - We herein describe a case of hypercalcemic crisis in a 52-year-old Japanese woman. She suffered from thirst and fatigue for one month. Her serum calcium (a) levels were 19.0 mg/dL, and she was diagnosed with hypercalcemic crisis. Circulating levels of parathyroid and thyroid hormones were elevated. She was diagnosed with primary hyperparathyroidism accompanied by Graves' disease. Thyroparathyroidectomy was performed after circulating levels of Ca and thyroid hormones were normalized. Both of primary hyperparathyroidism and Graves' disease can contribute and accelerate hypercalcemia, resulting in a state of crisis. The possibility of their coexistence should therefore be taken into consideration in cases of hypercalcemia. SN - 1349-7235 UR - https://www.unboundmedicine.com/medline/citation/25832948/Hypercalcemic_crisis_due_to_primary_hyperparathyroidism_occurring_concomitantly_with_Graves'_disease L2 - https://dx.doi.org/10.2169/internalmedicine.54.2605 DB - PRIME DP - Unbound Medicine ER -