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Efficacy and safety of 120-W thulium:yttrium-aluminum-garnet vapoenucleation of prostates compared with holmium laser enucleation of prostates for benign prostatic hyperplasia.
Chin Med J (Engl). 2015 Apr 05; 128(7):884-9.CM

Abstract

BACKGROUND

This study compared the efficacy and safety between 120-W thulium:yttrium-aluminum-garnet (Tm:YAG) vapoenucleation of prostates (ThuVEP) and holmium laser enucleation of prostates (HoLEP) for patients with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).

METHODS

A retrospective analysis of 88 consecutive patients with symptomatic BPH was carried out, who underwent either 120-W ThuVEP or HoLEP nonrandomly. Patient demographics and peri-operative and 12-month follow-up data were analyzed with the International Prostate Symptom Score (IPSS), quality of life (QoL) score, maximum flow rate (Qmax), postvoid residual urine volume (PVR), and rates of peri-operative and late complications.

RESULTS

The patients in each group showed no significant difference in preoperative parameters. Compared with the HoLEP group, patients in the 120-W ThuVEP group required significantly shorter time for laser enucleation (58.3 ± 12.8 min vs. 70.5 ± 22.3 min, P = 0.003), and resulted in a significant superiority in laser efficiency (resected prostate weight/laser enucleation time) for 120-W Tm:YAG laser compared to holmium:YAG laser (0.69 ± 0.18 vs. 0.61 ± 0.19, P = 0.048). During 1, 6, and 12 months of follow-ups, the procedures did not demonstrate a significant difference in IPSS, QoL score, Qmax, or PVR (P > 0.05). Mean peri-operative decrease of hemoglobin in the HoLEP group was similar to the ThuVEP group (17.1 ± 12.0 g/L vs. 15.2 ± 10.1 g/L, P = 0.415). Early and late incidences of complications were low and did not differ significantly between the two groups of 120-W ThuVEP and HoLEP patients (P > 0.05).

CONCLUSIONS

120-W ThuVEP and HoLEP are potent, safe and efficient modalities of minimally invasive surgeries for patients with LUTS due to BPH. Compared with HoLEP, 120-W ThuVEP offers advantages of reduction of laser enucleation time and improvement of laser efficiency.

Authors+Show Affiliations

No affiliation info availableDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25836607

Citation

Hong, Kai, et al. "Efficacy and Safety of 120-W Thulium:yttrium-aluminum-garnet Vapoenucleation of Prostates Compared With Holmium Laser Enucleation of Prostates for Benign Prostatic Hyperplasia." Chinese Medical Journal, vol. 128, no. 7, 2015, pp. 884-9.
Hong K, Liu YQ, Lu J, et al. Efficacy and safety of 120-W thulium:yttrium-aluminum-garnet vapoenucleation of prostates compared with holmium laser enucleation of prostates for benign prostatic hyperplasia. Chin Med J. 2015;128(7):884-9.
Hong, K., Liu, Y. Q., Lu, J., Xiao, C. L., Huang, Y., & Ma, L. L. (2015). Efficacy and safety of 120-W thulium:yttrium-aluminum-garnet vapoenucleation of prostates compared with holmium laser enucleation of prostates for benign prostatic hyperplasia. Chinese Medical Journal, 128(7), 884-9. https://doi.org/10.4103/0366-6999.154282
Hong K, et al. Efficacy and Safety of 120-W Thulium:yttrium-aluminum-garnet Vapoenucleation of Prostates Compared With Holmium Laser Enucleation of Prostates for Benign Prostatic Hyperplasia. Chin Med J. 2015 Apr 5;128(7):884-9. PubMed PMID: 25836607.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy and safety of 120-W thulium:yttrium-aluminum-garnet vapoenucleation of prostates compared with holmium laser enucleation of prostates for benign prostatic hyperplasia. AU - Hong,Kai, AU - Liu,Yu-Qing, AU - Lu,Jian, AU - Xiao,Chun-Lei, AU - Huang,Yi, AU - Ma,Lu-Lin, PY - 2015/4/4/entrez PY - 2015/4/4/pubmed PY - 2015/9/29/medline SP - 884 EP - 9 JF - Chinese medical journal JO - Chin. Med. J. VL - 128 IS - 7 N2 - BACKGROUND: This study compared the efficacy and safety between 120-W thulium:yttrium-aluminum-garnet (Tm:YAG) vapoenucleation of prostates (ThuVEP) and holmium laser enucleation of prostates (HoLEP) for patients with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). METHODS: A retrospective analysis of 88 consecutive patients with symptomatic BPH was carried out, who underwent either 120-W ThuVEP or HoLEP nonrandomly. Patient demographics and peri-operative and 12-month follow-up data were analyzed with the International Prostate Symptom Score (IPSS), quality of life (QoL) score, maximum flow rate (Qmax), postvoid residual urine volume (PVR), and rates of peri-operative and late complications. RESULTS: The patients in each group showed no significant difference in preoperative parameters. Compared with the HoLEP group, patients in the 120-W ThuVEP group required significantly shorter time for laser enucleation (58.3 ± 12.8 min vs. 70.5 ± 22.3 min, P = 0.003), and resulted in a significant superiority in laser efficiency (resected prostate weight/laser enucleation time) for 120-W Tm:YAG laser compared to holmium:YAG laser (0.69 ± 0.18 vs. 0.61 ± 0.19, P = 0.048). During 1, 6, and 12 months of follow-ups, the procedures did not demonstrate a significant difference in IPSS, QoL score, Qmax, or PVR (P > 0.05). Mean peri-operative decrease of hemoglobin in the HoLEP group was similar to the ThuVEP group (17.1 ± 12.0 g/L vs. 15.2 ± 10.1 g/L, P = 0.415). Early and late incidences of complications were low and did not differ significantly between the two groups of 120-W ThuVEP and HoLEP patients (P > 0.05). CONCLUSIONS: 120-W ThuVEP and HoLEP are potent, safe and efficient modalities of minimally invasive surgeries for patients with LUTS due to BPH. Compared with HoLEP, 120-W ThuVEP offers advantages of reduction of laser enucleation time and improvement of laser efficiency. SN - 2542-5641 UR - https://www.unboundmedicine.com/medline/citation/25836607/Efficacy_and_safety_of_120_W_thulium:yttrium_aluminum_garnet_vapoenucleation_of_prostates_compared_with_holmium_laser_enucleation_of_prostates_for_benign_prostatic_hyperplasia_ L2 - http://dx.doi.org/10.4103/0366-6999.154282 DB - PRIME DP - Unbound Medicine ER -