Tags

Type your tag names separated by a space and hit enter

Antioxidant activity and chemical composition of essential oils of three aromatic plants from La Rioja province.
Pharm Biol. 2016; 54(1):168-73.PB

Abstract

CONTEXT

The use of many traditional medicinal plants is often hampered by the absence of a proper biochemical characterization, which is essential to identify the bioactive compounds present in it. The essential oils (EOs) of three native species from the La Rioja province were analyzed: Lippia turbinata Griseb and Lippia integrifolia (Griseb.) Hieron (Verbenaceae), and Clinopodium gilliesii (Benth.) Kuntze (Lamiaceae).

OBJECTIVE

The aim of this study was to evaluate their EOs antioxidant activity (AA) and their chemical composition.

MATERIALS AND METHODS

EOs were analyzed by gas chromatography-mass spectrometry (GC-MS). To enhance the aqueous solubilization of the EOs, EO-water emulsions were prepared (concentration range of 0.1-6 mg mL(-1)). AA was determined using ABTS, DPPH, and peroxyl radical scavenging assays, as well as by the β-carotene bleaching test.

RESULTS

Piperitenone oxide was a major constituent in L. turbinata, pulegone and piperitenone oxide in C. gilliesii, and β-caryophyllene in L. integrifolia. Lippia turbinata EO was the most active ABTS and DPPH radical scavenger (SC50 values of 0.40 ± 0.14 and 0.74 ± 0.08 mg mL(-1), respectively). Clinopodium gilliesii EO exhibited the highest hydrogen peroxide scavenging activity (SC25 value = 1.52 ± 0.27 mg mL(-1)). In the β-carotene assay, L. turbinata EO was more effective at inhibiting lipid peroxidation than the other two oils (IC25 value = 0.15 ± 0.04 mg mL(-1)).

CONCLUSION

Our results suggest that the AA observed can be justified by the presence of oxygenated monoterpenes, mainly piperitenone oxide. Finally, L. turbinata EO might be used as a safe natural antioxidant and food preservative in the food and cosmetic industries.

Authors+Show Affiliations

a Departamento de Ciencias Básicas y Tecnológicas , Universidad Nacional de Chilecito , Chilecito , La Rioja , Argentina .b INQUINOA-CONICET, Universidad Nacional de Tucumán , Tucumán , Argentina , and.c Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán , Tucumán , Argentina.c Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán , Tucumán , Argentina.c Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán , Tucumán , Argentina.b INQUINOA-CONICET, Universidad Nacional de Tucumán , Tucumán , Argentina , and.a Departamento de Ciencias Básicas y Tecnológicas , Universidad Nacional de Chilecito , Chilecito , La Rioja , Argentina .

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25865139

Citation

Barbieri, Natalia, et al. "Antioxidant Activity and Chemical Composition of Essential Oils of Three Aromatic Plants From La Rioja Province." Pharmaceutical Biology, vol. 54, no. 1, 2016, pp. 168-73.
Barbieri N, Costamagna M, Gilabert M, et al. Antioxidant activity and chemical composition of essential oils of three aromatic plants from La Rioja province. Pharm Biol. 2016;54(1):168-73.
Barbieri, N., Costamagna, M., Gilabert, M., Perotti, M., Schuff, C., Isla, M. I., & Benavente, A. (2016). Antioxidant activity and chemical composition of essential oils of three aromatic plants from La Rioja province. Pharmaceutical Biology, 54(1), 168-73. https://doi.org/10.3109/13880209.2015.1028077
Barbieri N, et al. Antioxidant Activity and Chemical Composition of Essential Oils of Three Aromatic Plants From La Rioja Province. Pharm Biol. 2016;54(1):168-73. PubMed PMID: 25865139.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant activity and chemical composition of essential oils of three aromatic plants from La Rioja province. AU - Barbieri,Natalia, AU - Costamagna,Milena, AU - Gilabert,Miguel, AU - Perotti,Marina, AU - Schuff,Carola, AU - Isla,María Inés, AU - Benavente,Alba, Y1 - 2015/04/13/ PY - 2015/4/14/entrez PY - 2015/4/14/pubmed PY - 2016/9/22/medline KW - Biological activity KW - Clinopodium gilliesii KW - Lippia integrifolia KW - Lippia turbinata KW - piperitenone oxide SP - 168 EP - 73 JF - Pharmaceutical biology JO - Pharm Biol VL - 54 IS - 1 N2 - CONTEXT: The use of many traditional medicinal plants is often hampered by the absence of a proper biochemical characterization, which is essential to identify the bioactive compounds present in it. The essential oils (EOs) of three native species from the La Rioja province were analyzed: Lippia turbinata Griseb and Lippia integrifolia (Griseb.) Hieron (Verbenaceae), and Clinopodium gilliesii (Benth.) Kuntze (Lamiaceae). OBJECTIVE: The aim of this study was to evaluate their EOs antioxidant activity (AA) and their chemical composition. MATERIALS AND METHODS: EOs were analyzed by gas chromatography-mass spectrometry (GC-MS). To enhance the aqueous solubilization of the EOs, EO-water emulsions were prepared (concentration range of 0.1-6 mg mL(-1)). AA was determined using ABTS, DPPH, and peroxyl radical scavenging assays, as well as by the β-carotene bleaching test. RESULTS: Piperitenone oxide was a major constituent in L. turbinata, pulegone and piperitenone oxide in C. gilliesii, and β-caryophyllene in L. integrifolia. Lippia turbinata EO was the most active ABTS and DPPH radical scavenger (SC50 values of 0.40 ± 0.14 and 0.74 ± 0.08 mg mL(-1), respectively). Clinopodium gilliesii EO exhibited the highest hydrogen peroxide scavenging activity (SC25 value = 1.52 ± 0.27 mg mL(-1)). In the β-carotene assay, L. turbinata EO was more effective at inhibiting lipid peroxidation than the other two oils (IC25 value = 0.15 ± 0.04 mg mL(-1)). CONCLUSION: Our results suggest that the AA observed can be justified by the presence of oxygenated monoterpenes, mainly piperitenone oxide. Finally, L. turbinata EO might be used as a safe natural antioxidant and food preservative in the food and cosmetic industries. SN - 1744-5116 UR - https://www.unboundmedicine.com/medline/citation/25865139/Antioxidant_activity_and_chemical_composition_of_essential_oils_of_three_aromatic_plants_from_La_Rioja_province_ L2 - https://www.tandfonline.com/doi/full/10.3109/13880209.2015.1028077 DB - PRIME DP - Unbound Medicine ER -