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Seroprevalence of Helicobacter pylori and Hepatitis A Virus among Children in Rural Central Taiwan.
Jpn J Infect Dis. 2015; 68(6):494-503.JJ

Abstract

Helicobacter pylori and hepatitis A virus (HAV) are thought to have similar routes of transmission and epidemiology. This study investigated the seroprevalence of these 2 pathogens among children in rural, central Taiwan. Serum samples were collected from 856 children between 2010 and 2012 and levels of anti-HAV and anti-H. pylori antibodies were measured by ELISA. Questionnaires were used to investigate possible risk factors. The overall H. pylori and HAV infection rates were 6% and 0.8%, respectively. There was a significant difference in H. pylori infection rates (P value=0.008), but not HAV infection rates, between different age groups. H. pylori infection rates were significantly higher in children whose mothers had lower education levels. In contrast, HAV infection rates were significantly higher in children whose fathers had lower education levels. The risk of HAV infection was also 14.20-fold higher in children whose family members had traveled to China or Southeast Asia. No significant correlation was found between H. pylori and HAV seropositivity. The seroprevalences of H. pylori and HAV were low in rural central Taiwan. Universal HAV vaccination is highly recommended to prevent outbreak due to low seroprevalence.

Authors+Show Affiliations

Department of Pediatrics, Chang-Bing Show Chwan Memorial Hospital.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25866110

Citation

Wu, Meng-Che, et al. "Seroprevalence of Helicobacter Pylori and Hepatitis a Virus Among Children in Rural Central Taiwan." Japanese Journal of Infectious Diseases, vol. 68, no. 6, 2015, pp. 494-503.
Wu MC, Sung CH, Chang YC, et al. Seroprevalence of Helicobacter pylori and Hepatitis A Virus among Children in Rural Central Taiwan. Jpn J Infect Dis. 2015;68(6):494-503.
Wu, M. C., Sung, C. H., Chang, Y. C., Ho, C. L., Wu, C. C., Wu, K. H., Lee, C. Y., & Yang, K. D. (2015). Seroprevalence of Helicobacter pylori and Hepatitis A Virus among Children in Rural Central Taiwan. Japanese Journal of Infectious Diseases, 68(6), 494-503. https://doi.org/10.7883/yoken.JJID.2014.321
Wu MC, et al. Seroprevalence of Helicobacter Pylori and Hepatitis a Virus Among Children in Rural Central Taiwan. Jpn J Infect Dis. 2015;68(6):494-503. PubMed PMID: 25866110.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Seroprevalence of Helicobacter pylori and Hepatitis A Virus among Children in Rural Central Taiwan. AU - Wu,Meng-Che, AU - Sung,Chia-Hsing, AU - Chang,Yu-Chuan, AU - Ho,Chi-Lin, AU - Wu,Chih-Chiang, AU - Wu,Kuei-Hua, AU - Lee,Chun-Yi, AU - Yang,Kuen-Der, Y1 - 2015/04/10/ PY - 2015/4/14/entrez PY - 2015/4/14/pubmed PY - 2016/8/30/medline SP - 494 EP - 503 JF - Japanese journal of infectious diseases JO - Jpn J Infect Dis VL - 68 IS - 6 N2 - Helicobacter pylori and hepatitis A virus (HAV) are thought to have similar routes of transmission and epidemiology. This study investigated the seroprevalence of these 2 pathogens among children in rural, central Taiwan. Serum samples were collected from 856 children between 2010 and 2012 and levels of anti-HAV and anti-H. pylori antibodies were measured by ELISA. Questionnaires were used to investigate possible risk factors. The overall H. pylori and HAV infection rates were 6% and 0.8%, respectively. There was a significant difference in H. pylori infection rates (P value=0.008), but not HAV infection rates, between different age groups. H. pylori infection rates were significantly higher in children whose mothers had lower education levels. In contrast, HAV infection rates were significantly higher in children whose fathers had lower education levels. The risk of HAV infection was also 14.20-fold higher in children whose family members had traveled to China or Southeast Asia. No significant correlation was found between H. pylori and HAV seropositivity. The seroprevalences of H. pylori and HAV were low in rural central Taiwan. Universal HAV vaccination is highly recommended to prevent outbreak due to low seroprevalence. SN - 1884-2836 UR - https://www.unboundmedicine.com/medline/citation/25866110/Seroprevalence_of_Helicobacter_pylori_and_Hepatitis_A_Virus_among_Children_in_Rural_Central_Taiwan_ DB - PRIME DP - Unbound Medicine ER -